干扰素诱导四核苷酸重复序列(IFIT)家族蛋白在癌症中的作用

Title:Roles of Interferon Induced Protein with Tetratricopeptide Repeats (IFIT) Family in Cancer

Volume: 28 Issue: 25

关键词: 癌症，干扰素诱导蛋白，四三肽重复序列，IFIT，生物标志物，预后因子。

摘要: The Interferon-induced protein with tetratricopeptide repeats (IFIT) family is an important component of the antiviral immune response. There are currently four known IFIT family members in humans, namely IFIT1, IFIT2, IFIT3 and IFIT5. Recent discoveries have brought attention to the significant roles of IFITs in cancer. This review summarises current knowledge on the biological roles of different IFIT proteins in various types of malignant neoplasm, and highlights the potential use of these molecules as cancer biomarkers and prognostic factors.

Cite this article as:

Roles of Interferon Induced Protein with Tetratricopeptide Repeats (IFIT) Family in Cancer, Current Medicinal Chemistry 2021; 28 (25) . https://dx.doi.org/10.2174/0929867328666210617105209