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Current Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 0929-8673
ISSN (Online): 1875-533X

Review Article

COVID-19: The Significance of Platelets, Mitochondria, Vitamin D, Serotonin and the Gut Microbiota

Author(s): István Bókkon*, Gábor Kapócs, András Vucskits, Attila Erdöfi-Szabó, Jan Vagedes , Felix Scholkmann and Henrik Szöke

Volume 28, Issue 37, 2021

Published on: 24 August, 2021

Page: [7634 - 7657] Pages: 24

DOI: 10.2174/0929867328666210526100147

Price: $65

Abstract

We provide a brief review of the significance of platelets, mitochondria, vitamin D, serotonin, and the gut microbiome in COVID-19. We hypothesize that hyperactive platelets and mitochondrial dysfunction, as well as low vitamin D level, gut dysbiosis, and increased serum serotonin produced by enterochromaffin cells, may all represent important aspects in the pathophysiology of COVID-19.

Keywords: Platelets, mitochondria, vitamin D, serotonin, gut-brain axis, COVID-19, SARS-CoV-2.


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