Abstract
Alzheimer’s Disease (AD) is one of the major neurodegenerative disorders. Deposition of amyloid fibrils and tau protein is associated with various pathological symptoms. Currently, limited medication is available for AD treatment. Most of the drugs are basically cholinesterase inhibitors and associated with various side effects. Natural plant products have shown potential as a therapeutic agent for the treatment of AD symptoms. A variety of secondary metabolites such as flavonoids, tannins, terpenoids, alkaloids, and phenols are used to reduce the progression of the disease. Plant products have fewer or no side effects and are easily available. The present review gives a detailed account of the potential of natural plant products against AD symptoms.
Keywords: Alzheimer's disease, natural plant products, pathogenesis, treatment, AD symptoms, secondary metabolites.
Graphical Abstract
CNS & Neurological Disorders - Drug Targets
Title:Role of Natural Plant Products Against Alzheimer’s Disease
Volume: 20 Issue: 10
Author(s): Himanshi Varshney and Yasir Hasan Siddique*
Affiliation:
- Drosophila Transgenic Laboratory, Section of Genetics, Department of Zoology, Faculty of Life Sciences, Aligarh Muslim University, Aligarh 202002, Uttar Pradesh,India
Keywords: Alzheimer's disease, natural plant products, pathogenesis, treatment, AD symptoms, secondary metabolites.
Abstract: Alzheimer’s Disease (AD) is one of the major neurodegenerative disorders. Deposition of amyloid fibrils and tau protein is associated with various pathological symptoms. Currently, limited medication is available for AD treatment. Most of the drugs are basically cholinesterase inhibitors and associated with various side effects. Natural plant products have shown potential as a therapeutic agent for the treatment of AD symptoms. A variety of secondary metabolites such as flavonoids, tannins, terpenoids, alkaloids, and phenols are used to reduce the progression of the disease. Plant products have fewer or no side effects and are easily available. The present review gives a detailed account of the potential of natural plant products against AD symptoms.
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Cite this article as:
Varshney Himanshi and Siddique Hasan Yasir *, Role of Natural Plant Products Against Alzheimer’s Disease, CNS & Neurological Disorders - Drug Targets 2021; 20 (10) . https://dx.doi.org/10.2174/1871527320666210420135437
DOI https://dx.doi.org/10.2174/1871527320666210420135437 |
Print ISSN 1871-5273 |
Publisher Name Bentham Science Publisher |
Online ISSN 1996-3181 |
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