Chemical Constituents and Biological Activities of the Genus Flindersia
(Rutaceae)

Lara Pessanha    Soares    Nascimento; Michel    de Souza    Passos; Thalya Soares    Ribeiro    Nogueira; Mayara    Barreto de Souza    Arantes; Noemi    Oliveira    Monteiro; Samyra    Imad da Silva    Boeno; Antônio    Sérgio Nascimento    Moreira; Milena    Gonçalves Curcino    Vieira; Almir    Ribeiro   de Carvalho Júnior; Raimundo       Braz-Filho; Ivo José    Curcino    Vieira

doi:10.2174/1570193X18666210218213410

Abstract

The genus Flindersia comprises 17 species distributed in Australia, New Caledonia, New Guinea, and the Maluku Islands. With a variety of classes of secondary metabolites, including terpenes, alkaloids, lignans, flavonoids, coumarins, among other compounds, to date, the genus has not been widely studied phytochemically, having more value in the timber industry. However, the objective of this review is to gather the necessary information for future research on this genus, for the inclusion of new chemical constituents and biological activities. Thus, we show that the genus Flindersia has more than 160 isolated or identified compounds. In addition, the alkaloids in this genus confer antimalarial activity.

Keywords: Flindersia, secondary metabolites, biological activities, terpenes, alkaloids, phenolic compounds, antifeedant activity

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DOI https://dx.doi.org/10.2174/1570193X18666210218213410	Print ISSN 1570-193X
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