摘要
2019冠状病毒病(COVID-19)是由严重急性呼吸综合征冠状病毒2型(SARS-CoV-2)引起的高致病性、高传染性病毒性疾病,起源于中国中部湖北省武汉市,在世界范围内迅速传播。SARSCoV- 2的基因组序列与蝙蝠源的严重急性呼吸综合征样(如SARS)冠状病毒具有系统发育相关性;因此蝙蝠可能是主要的宿主。目前,没有临床获批的抗疫疫苗或抗病毒药物。然而,一些广谱抗病毒药物已经在临床研究中被评估用于治疗COVID-19,并使得患者病情得以改善。在这方面,正在研究其他疗法,如抗病毒药物、抗体、干细胞和血浆疗法。本文综述了COVID-19感染的发生、致病性和基因组结构。这项研究的主要重点是可能对SARS-CoV-2有效的治疗方法。
关键词: COVID-19,新型冠状病毒,治疗性,SARS-CoV-2,抗病毒,SARS-CoV-19。
Current Molecular Medicine
Title:Therapeutic Measures for the Novel Coronavirus: A Review of Current Status and Future Perspective
Volume: 21 Issue: 7
关键词: COVID-19,新型冠状病毒,治疗性,SARS-CoV-2,抗病毒,SARS-CoV-19。
摘要: The coronavirus disease 19 (COVID-19) is a highly pathogenic and transmissible viral disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which originated in the city of Wuhan, Hubei Province, Central China and spread quickly around the world. The genome sequence of SARSCoV- 2 is phylogenetically related to bat-derived severe acute respiratory syndrome-like (SARS-like) coronaviruses; therefore bats could be the possible primary reservoirs. At present, there are no clinically approved vaccines or specific antiviral drugs for COVID- 19. However, several broad-spectrum antiviral drugs have been evaluated against COVID-19 in clinical studies and resulted in the improvement of patients. In this regard, other therapies such as antiviral drugs, antibodies, stem cells and plasma therapy are being studied. In the current study, we reviewed the emergence, pathogenicity and the genome structure of COVID-19 infection. The main focus of this study is on the therapeutic approaches that may be effective against SARS-CoV-2.
Export Options
About this article
Cite this article as:
Therapeutic Measures for the Novel Coronavirus: A Review of Current Status and Future Perspective, Current Molecular Medicine 2021; 21 (7) . https://dx.doi.org/10.2174/1566524020666201203170230
DOI https://dx.doi.org/10.2174/1566524020666201203170230 |
Print ISSN 1566-5240 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5666 |

- Author Guidelines
- Bentham Author Support Services (BASS)
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
New Developments In Treatment After Lung Transplantation
Current Pharmaceutical Design Docking and Molecular Dynamics Study on the Inhibitory Activity of Novel Inhibitors on Epidermal Growth Factor Receptor (EGFR)
Medicinal Chemistry Molecular Modeling Studies of Peptide Drug Candidates against SARS
Medicinal Chemistry COVID-19 Vaccination in Children: An Open Question
Current Pediatric Reviews COVID-19 Related Publications Focusing on Cancer: Systematic Review of a Delicate Balance
Clinical Cancer Drugs Small Molecules' Multi-Metabolic Pathways Prediction Using Physico- Chemical Features and Multi-Task Learning Method.
Current Bioinformatics Nutritional Intervention for the Treatment and Prevention Against Novel Coronavirus-19
Coronaviruses Impact of COVID-19 on Gender Equality, Sexual and Reproductive Health Rights of Adolescent Girls and Young Women: A Narrative Review
Current Women`s Health Reviews The Impact of Crystallographic Data for the Development of Machine Learning Models to Predict Protein-Ligand Binding Affinity
Current Medicinal Chemistry An Augmented Passive Immune Therapy to Treat Fulminant Bacterial Infections
Recent Patents on Anti-Infective Drug Discovery CT Diagnosis of Coronavirus Infection
Current Medical Imaging The Undiscovered Potential of Essential Oils for Treating SARS-CoV-2 (COVID-19)
Current Pharmaceutical Design Caring for HIV-Infected Patients in the ICU in The Highly Active Antiretroviral Therapy Era
Current HIV Research Quaternary Structure, Substrate Selectivity and Inhibitor Design for SARS 3C-Like Proteinase
Current Pharmaceutical Design Pseudotyping Viral Vectors With Emerging Virus Envelope Proteins
Current Gene Therapy Potential Leads from Liquorice Against SARS-CoV-2 Main Protease using Molecular Docking Simulation Studies
Combinatorial Chemistry & High Throughput Screening The Linkage “Body Mass Index-Insomnia Levels-Eating Disorder Flexibility” in Italian Nurses During the Covid-19 Outbreak: A Psychoendocrinological Employment Disease
Endocrine, Metabolic & Immune Disorders - Drug Targets Systemic Treatments for Adult Patients with Moderate-to-Severe Psoriasis: Consensus Statements for the United Arab Emirates
New Emirates Medical Journal An Overview on COVID-19: Clinical Features, Treatment and Prevention
Coronaviruses Coronavirus (COVID-19) Outbreak: A Test of Viral Muscle Versus the Human Tussle
Applied Clinical Research, Clinical Trials and Regulatory Affairs