Abstract
This review summarizes the outbreak of viruses causing the fatal disease, which is highly pathogenic and efficiently transmitted from human to human. This first began in Wuhan, China, and now turned into an epidemic situation worldwide. A novel coronavirus (2019-nCoV) or severe acute respiratory syndrome coronavirus(SARS-CoV)-2 belongs to β-coronavirus genera originated in bats due to highly identical genome which leads to bat coronavirus. This review highlights the study of Indian Council of Medical Research, India, which determined the detection of pathogenic coronavirus in two different species of Indian bats. Indian Council of Medical Research, India, has successfully isolated the COVID-19 virus strain which was the first step towards diagnosis and the development of vaccines in the country. The outbreaks of coronavirus received worldwide attention for overcoming the challenges faced during this current pandemic as there is no clinically approved antiviral drug or vaccine available yet. However, preventive measures and different treatments were taken to cope with this viral outbreak. In response to this global outbreak, this review tries to explain the Virology, Epidemiology and pathogenesis, and discusses the diagnosis and treatment strategies of COVID-19. This review emphasizes the current update of COVID-19.
Keywords: Novel coronavirus, severe acute respiratory syndromes, epidemiology, world health organization, convalescent plasma, virus research, diagnostic laboratory.
Graphical Abstract
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