Abstract
In the past 20 years, photosensitisers have found a niche in the photodynamic treatment of accessible tumours (PDT). Most of the therapeutics involved in this approach are porphyrin-based natural products or derivatives. However, there is a range of other photodynamic agents derived from natural sources – either via direct extraction/purification, or via semisynthesis - currently being trialled both for anticancer PDT and the related antimicrobial application, covering areas such as wound disinfection and blood product sterilisation. The following review covers the advances made in the potential photoantimicrobial application of natural product photosensitisers and their derivatives.
Keywords: Antimicrobial, photosensitiser, singlet oxygen, porphyrin, perylenequinonoid, anthraquinone, isoquinoline, furocoumarin
Current Bioactive Compounds
Title: Natural Product Photoantimicrobials
Volume: 3 Issue: 4
Author(s): M. Wainwright
Affiliation:
Keywords: Antimicrobial, photosensitiser, singlet oxygen, porphyrin, perylenequinonoid, anthraquinone, isoquinoline, furocoumarin
Abstract: In the past 20 years, photosensitisers have found a niche in the photodynamic treatment of accessible tumours (PDT). Most of the therapeutics involved in this approach are porphyrin-based natural products or derivatives. However, there is a range of other photodynamic agents derived from natural sources – either via direct extraction/purification, or via semisynthesis - currently being trialled both for anticancer PDT and the related antimicrobial application, covering areas such as wound disinfection and blood product sterilisation. The following review covers the advances made in the potential photoantimicrobial application of natural product photosensitisers and their derivatives.
Export Options
About this article
Cite this article as:
Wainwright M., Natural Product Photoantimicrobials, Current Bioactive Compounds 2007; 3 (4) . https://dx.doi.org/10.2174/157340707783220202
DOI https://dx.doi.org/10.2174/157340707783220202 |
Print ISSN 1573-4072 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6646 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Aminobisphosphonates as New Weapons for γ δ T Cell-Based Immunotherapy of Cancer
Current Medicinal Chemistry Induction and Escalation Therapies in Multiple Sclerosis
Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry Inflammation and Antiangiogenesis in Cancer
Current Medicinal Chemistry ROS1 Kinase Inhibitors for Molecular-Targeted Therapies
Current Medicinal Chemistry The Nuclear Orphan Receptor NR4A1 and NR4A3 as Tumor Suppressors in Hematologic Neoplasms
Current Drug Targets Biological Modulation by Lectins and Their Ligands in Tumor Progression and Metastasis
Anti-Cancer Agents in Medicinal Chemistry Role of Oxidative Stress in Hepatitis C Virus Induced Hepatocellular Carcinoma
Current Cancer Drug Targets The ALK Gene, An Attractive Target for Inhibitor Development
Current Topics in Medicinal Chemistry Nanomaterials in the Pharmaceuticals: Occurrence, Behaviour and Applications
Current Pharmaceutical Design Structure of the Epidermal Growth Factor Receptor Gene and Intron Recombination in Human Gliomas
Current Genomics Tumor Necrosis Factor-α-Mediated Pulmonary Endothelial Barrier Dysfunction
Current Respiratory Medicine Reviews From French Paradox to Cancer Treatment: Anti-cancer Activities and Mechanisms of Resveratrol
Anti-Cancer Agents in Medicinal Chemistry Decreasing the Metastatic Potential in Cancers - Targeting the Heparan Sulfate Proteoglycans
Current Drug Targets A Pilot Study Evaluating Combinatorial and Simultaneous Delivery of Polyethylenimine-Plasmid DNA Complexes Encoding for VEGF and PDGF for Bone Regeneration in Calvarial Bone Defects
Current Pharmaceutical Biotechnology Anti-Angiogenesis Activities of Dietary Constituents and Health Foods with Potential Anti-Hepatocellular Carcinoma Activity
Recent Patents on Biomarkers From Nature to Market: Examples of Natural Products that Became Drugs
Recent Patents on Biotechnology CRISPR/Cas9 Genome Editing Tool: A Promising Tool for Therapeutic Applications on Respiratory Diseases
Current Gene Therapy Tubulin Maytansine Site Binding Ligands and their Applications as MTAs and ADCs for Cancer Therapy
Current Medicinal Chemistry A Descriptive Analysis of Post-Chemotherapy Development of Interstitial Lung Disease Using Spontaneous Reporting Data in Japan
Current Drug Safety Active Tumor Targeting of Nanomaterials Using Folic Acid, Transferrin and Integrin Receptors
Current Drug Discovery Technologies