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Current Nutrition & Food Science

Editor-in-Chief

ISSN (Print): 1573-4013
ISSN (Online): 2212-3881

Review Article

Traditional Use, Phytochemicals and Pharmacological Activity of Salvadora persica: A Review

Author(s): Dharmendra Kumar* and Pramod K. Sharma

Volume 17, Issue 3, 2021

Published on: 07 August, 2020

Page: [302 - 309] Pages: 8

DOI: 10.2174/1573401316999200807205224

Price: $65

Abstract

Salvadora persica L., also known as Miswak, Peelu and Arak, is used traditionally as a source of food, cosmetics, fuel and medicine. The most common traditional use of Salvadora persica sticks is tooth cleaning. Other traditional uses of Salvadora persica are in diabetes, arthritis, constipation, fever, cold, malaria, viral infection, gonorrhea, worms, antidotes, stimulators, laxatives and various veterinary problems, such as poor milk production, abdominal disorder, diarrhea, etc. Now traditional uses of Salvadora persica have been scientifically proved in modern research. Various pharmacological activities of Salvadora persica as reported in modern research were anti- microbial, antifungal, anti-inflammatory, analgesic, antiulcer, anticonvulsant, antifertility, wound healing, anthelmintic, antidepressant, anticancer, etc. These pharmacological activities are due to the presence of many phytochemicals in Salvadora persica. Phytochemicals present in Salvadora persica are alkaloids, glycosides, tannins, flavonoids, proteins, terpenoids and sterols. The aim of this review is to provide various traditional use of Salvadora persica proved by modern research, and highlight its pharmacological activity and phytochemicals. This review article may be used to set a new research hypothesis with reference to traditional use.

Keywords: Salvadora persica, traditional use, phytochemical, anticancer, herbal anticancer, miswak.

Graphical Abstract

[1]
Anthoney ST, Lasiti T. Timothy. Phytochemical and antibacterial evaluation of ethanolic extract of Salvadora persica root extract against selected microorganism. Int J Bioassays 2015; 4(12): 4658-66.
[2]
Agroforestry Database 40 (Orwa et al2009) 2009.
[3]
Oliver-Bever B. Medicinal plants in tropical West Africa. UK: Cambridge University Press 1986.
[http://dx.doi.org/10.1017/CBO9780511753114]
[4]
Katerere DR, Luseba D. Ethnoveterinary botanical medicine: herbal medicines for animal health. Boca Raton: CRC Press 2010.
[http://dx.doi.org/10.1201/EBK1420045604]
[5]
Bizimana N. Traditional Veterinary Practice in Africa Deutsche Gesellschaft für Technische Zusammenarbeit (GTZ). GmbH, Eschborn 1994.
[6]
Toyang NJ, Wanyama J, Django S. Ethanovaterinary medicine: a practical approach for the treatment of cattle disease in Sub-Saharan Africa. 2nd ed. The Netherlands: Agromisa 2007. In:
[7]
Orwa C, Mutua A, Kindt R, Jamnadass R, Anthony S. Agroforestree database: a tree reference and selection guide version 4.0 World Agroforestry Centre, Kenya In: 2009.
[8]
Panda H. Herbs Cultivation and Medicinal Uses. 2nd ed. National Institute of Industrial Research 1999.
[9]
Trivedi PC. Medicinal Plants: Utilisation and Conservation, (2nd ed.), Jaipur, India: Aavishkar Publishers, Distributors 2009.
[10]
Panda H. Herbs Cultivation and Medicinal Uses. 2nd ed. India: National Institute of Industrial Research 1999.
[11]
Kimondo J, Miaron J, Mutai P, Njogu P. Ethnobotanical survey of food and medicinal plants of the Ilkisonko Maasai community in Kenya. J Ethnopharmacol 2015; 175: 463-9.
[http://dx.doi.org/10.1016/j.jep.2015.10.013] [PMID: 26456346]
[12]
Fratkin E. Traditional medicine and concepts of healing among Samburu pastoralists of Kenya. J Ethnobiol 1996; 16(1): 63-97.
[13]
Muthee JK, Gakuya DW, Mbaria JM, Kareru PG, Mulei CM, Njonge FK. Ethnobotanical study of anthelmintic and other medicinal plants traditionally used in Loitoktok district of Kenya. J Ethnopharmacol 2011; 135(1): 15-21.
[http://dx.doi.org/10.1016/j.jep.2011.02.005] [PMID: 21349318]
[14]
Kiringe JW. A survey of traditional health remedies used by the Maasai of Southern Kaijiado district, Kenya. Ethnobot Res Appl 2006; 4: 61-73.
[http://dx.doi.org/10.17348/era.4.0.61-74]
[15]
Ngaruiya GW. Reweaving stakeholder networks: promoting climate mitigation and Maasai culture using medicinal plants in Kenya. Ecosyst Serv 2015; 15: 103-12.
[http://dx.doi.org/10.1016/j.ecoser.2015.05.010]
[16]
Tsigemelak D, Dharani N, Kinyamario JI, Kiboi S. The utilization of medicinal plants by the Masaai community in arid lands of Kajiado county, Kenya. Int J Plant Anim Environ Sci (Ruse) 2016. 6(3): 1.
[17]
Bizimana N. Traditional Veterinary Practice in Africa Deutsche Gesellschaft für Technische Zusammenarbeit (GTZ). GmbH, Eschborn 1994.
[18]
Hope G. A literature survey of studies performed by master students at Département de Médecine Traditionelle (DMT) in Bamako. Mali: Universitetet i Oslo 2005.
[19]
Runyoro DKB, Ngassapa OD, Matee MIN, Joseph CC, Moshi MJ. Medicinal plants used by Tanzanian traditional healers in the management of Candida infections. J Ethnopharmacol 2006; 106(2): 158-65.
[http://dx.doi.org/10.1016/j.jep.2005.12.010] [PMID: 16458463]
[20]
Chhabra SC, Mahunnah RL, Mshiu EN. Plants used in traditional medicine in eastern Tanzania. V. Angiosperms (Passifloraceae to Sapindaceae). J Ethnopharmacol 1991; 33(1-2): 143-57.
[http://dx.doi.org/10.1016/0378-8741(91)90173-B] [PMID: 1943163]
[21]
Chinsembu KC, Negumbo J, Likando M, Mbangu A. An ethnobotanical study of medicinal plants used to treat livestock diseases in Onayena and Katima Mulilo, Namibia. S Afr J Bot 2014; 94: 101-7.
[http://dx.doi.org/10.1016/j.sajb.2014.06.007]
[22]
Teklehaymanot T, Giday M. Quantitative ethnobotany of medicinal plants used by Kara and Kwego semi-pastoralist people in lower Omo River Valley, Debub Omo Zone, Southern Nations, Nationalities and Peoples Regional State, Ethiopia. J Ethnopharmacol 2010; 130(1): 76-84.
[http://dx.doi.org/10.1016/j.jep.2010.04.013] [PMID: 20420888]
[23]
Eissa TA, Palomino OM, Carretero ME, Gómez-Serranillos MP. Ethnopharmacological study of medicinal plants used in the treatment of CNS disorders in Sinai Peninsula, Egypt. J Ethnopharmacol 2014; 151(1): 317-32.
[http://dx.doi.org/10.1016/j.jep.2013.10.041] [PMID: 24184194]
[24]
Goodman SM, Hobbs JJ. The ethnobotany of the Egyptian eastern desert: a comparison of common plant usage between two culturally distinct Bedouin groups. J Ethnopharmacol 1988; 23(1): 73-89.
[http://dx.doi.org/10.1016/0378-8741(88)90116-X] [PMID: 3419205]
[25]
Mahmoud T, Gairola S. Traditional knowledge and use of medicinal plants in the eastern desert of Egypt: a case study from Wadi El-Gemal National Park. J Medicinal Plants Stud 2013; 1(6): 10-7.
[26]
Ogbazghi W, Bein E. Assessment of non-wood forest products and their role in the livelihoods of rural communities in the Gash-Barka Region, Eritrea. Drylands Coordination Group Report No. 40 2006.
[27]
Samuelsson G, Farah MH, Claeson P, et al. Inventory of plants used in traditional medicine in Somalia. IV. Plants of the families Passifloraceae-Zygophyllaceae. J Ethnopharmacol 1993; 38(1): 1-29.
[http://dx.doi.org/10.1016/0378-8741(93)90075-G] [PMID: 8479201]
[28]
Parveen A, Upadhyay B, Roy S, Kumar A. Traditional uses of medicinal plants among the rural communities of Churu district in the Thar Desert, India. J Ethnopharmacol 2007; 113(3): 387-99.
[http://dx.doi.org/10.1016/j.jep.2007.06.010] [PMID: 17714898]
[29]
Patel HM, Patel NK. Sacred and medicinal plant diversity of Patan sacred grove of Patan district (N.G.). Life Sci Leafl 2017; 50-60.
[30]
Savithramma N, Sulochana Ch, Rao KN. Ethnobotanical survey of plants used to treat asthma in Andhra Pradesh, India. J Ethnopharmacol 2007; 113(1): 54-61.
[http://dx.doi.org/10.1016/j.jep.2007.04.004] [PMID: 17606346]
[31]
Rabari H. Ethnomedicinal value of plants found in Dhinodhar hills of Kachchh region of Gujarat. Int J Pharma Bio Sci 2016; 7(2): 160-3.
[32]
Kosalge SB, Fursule RA. Investigation of ethnomedicinal claims of some plants used by tribals of Satpuda Hills in India. J Ethnopharmacol 2009; 121(3): 456-61.
[http://dx.doi.org/10.1016/j.jep.2008.11.017] [PMID: 19100321]
[33]
Gunasekaran M, Balasubramanian P. Ethnomedicinal uses of Sthalavrikshas (temple trees) in Tamil Nadu, southern India. Ethnobot Res Appl 2012; 10: 253-68.
[http://dx.doi.org/10.17348/era.10.0.253-268]
[34]
Patel Y, Patel RM, Mahato AKR, Joshi PN. Status and diversity of ethno-medicinal plants of Dhinodhar hill, Kachchh district, Gujarat. Int J Plant Anim Environ Sci (Ruse) 2013; 3(1): 265-73.
[35]
Patel R, Mahato AKR, Kumar VV, Asari RV. Status of the medicinal plants in Tharawada-Gandher reserve forest of Kachchh, Gujarat and the ethnomedicinal practices of local community. J Medicinal Plants Stud 2013; 1(4): 1-10.
[36]
Ramzan S, Soelberg J, Jäger AK, Cantarero-Arévalo L. Traditional medicine among people of Pakistani descent in the capital region of Copenhagen. J Ethnopharmacol 2017; 196: 267-80.
[http://dx.doi.org/10.1016/j.jep.2016.11.048] [PMID: 27939419]
[37]
Yaseen G, Ahmad M, Sultana S, et al. Ethnobotany of medicinal plants in the Thar Desert (Sindh) of Pakistan. J Ethnopharmacol 2015; 163: 43-59.
[http://dx.doi.org/10.1016/j.jep.2014.12.053] [PMID: 25617748]
[38]
Sher H, Al-yemeni MN, Wijaya L. Ethnobotanical and antibacterial potential of Salvadora persica: a well known medicinal plant in Arab and Unani system of medicine. J Med Plants Res 2011; 5(7): 1224-9.
[39]
Malik S, Ahmad SS, Haider SI, Muzaffar A. Salvadoricine, a new alkaloid from the leaves of Salvadora persica. Tetrahedron Lett 1987; 28(2): 163-4.
[http://dx.doi.org/10.1016/S0040-4039(00)95675-2]
[40]
Alali F, Al-Lafi T. GC-MS analysis and bioactivity testing of the volatile oil from the leaves of the toothbrush tree Salvadora persica L. Nat Prod Res 2003; 17(3): 189-94.
[http://dx.doi.org/10.1080/1057563021000040790] [PMID: 12737403]
[41]
Kamil M, Ahmad F, Jayaraj AF, et al. Isolation and identification of a flavonol glycoside using high speed counter current chromatographic technique from the leaves of Salvadora persica. Pak J Sci Ind Res 2000; 43(4): 255-7.
[42]
Arora M, Kalia AN. Isolation and characterization of stigmasterol and β-sitosterol-d-glycoside from ethanolic extract of the stems of Salvadora persica linn. Int J Pharma Sci 2013; 5(1): 245-9.
[43]
Kasai R, Yamasaki K, Tanaka O, et al. Lignan glycoside from stems of Salvodora persica L. Phytochemistry 1992; 31(7): 2469-71.
[http://dx.doi.org/10.1016/0031-9422(92)83301-E]
[44]
Alali F, Hudaib M, Aburjai T, Khairallah K, Al-Hadidi N. GC-MS analysis and antimicrobial activity of the essential oil from the stem of the Jordanian toothbrush tree Salvadora persica. Pharm Biol 2004; 42(8): 577-80.
[http://dx.doi.org/10.1080/13880200490901834]
[45]
Khalil AT. Benzylamides from Salvadora persica. Arch Pharm Res 2006; 29(11): 952-6.
[http://dx.doi.org/10.1007/BF02969277] [PMID: 17146962]
[46]
Jain M, Saxena VK. Chemical constituents of the Stem of Salvadora persica. Acta Cienc Indica 1984; 10: 127.
[47]
Hyson JM Jr. History of the toothbrush. J Hist Dent 2003; 51(2): 73-80.
[PMID: 12846261]
[48]
Kamel MS, Ohtani K, Assaf MH, et al. Lignan glycosides from stems of Salvadora persica. Phytochemistry 1992; 31: 2469-71.
[http://dx.doi.org/10.1016/0031-9422(92)83301-E]
[49]
Abdel-Waheb SM, Selim MA. EI-Fiki NM. Investigation of the flavanoid content of Salvodora persica L. Bull Fac Pharm 1990; 28: 67-70.
[50]
Howaida F, Abdel R, Nils S, Whyatt AM, Francis GW. Volatile compounds in crude Salvadora persica extracts. Pharm Biol 2003; 41: 399-404.
[http://dx.doi.org/10.1076/phbi.41.6.399.17826]
[51]
Farag M, Abdel-Mageed WM, Basudan O, El-Gamal A. Persicaline, a new antioxidant sulphur-containing imidazoline alkaloid from Salvadora persica roots. Molecules 2018; 23(2): 483.
[http://dx.doi.org/10.3390/molecules23020483] [PMID: 29473845]
[52]
Kamil M, Jayaraj AF, Ahmed F, et al. Pharmacognostic and phytochemical studies on Salvadora persica. Pharm Pharmacol 1999; 227: 51-8.
[53]
Akhtar MS, Ajmal M. Significance of chewing-sticks (miswaks) in oral hygiene from a pharmacological view-point. J Pak Med Assoc 1981; 31(4): 89-95.
[PMID: 6785501]
[54]
Al lafi T, Ababneh H. The effect of the extract of the miswak (chewing sticks) used in Jordan and the Middle East on oral bacteria. Int Dent J 1995; 45(3): 218-22.
[PMID: 7558361]
[55]
Farooqi M, Srivastava JJ. The toothbrush tree (Salvadora persica). Crude. Drug Res 1968; 8: 1297-9.
[56]
Aumeeruddy MZ, Zengin G, Mahomoodally MF. A review of the traditional and modern uses of Salvadora persica L. (Miswak): Toothbrush tree of Prophet Muhammad. J Ethnopharmacol 2018; 213: 409-44.
[http://dx.doi.org/10.1016/j.jep.2017.11.030] [PMID: 29196134]
[57]
Khan M, Yusuf M, Al Robaian M, Ali M. Isolation and characterization of four novel β-Sitosteryl esters from Salvadora persica Linn. Nat Prod Res 2017; 1-9.
[PMID: 29092626]
[58]
Noumi E, Snoussi M, Merghni A, et al. Phytochemical composition, anti-biofilm and anti-quorum sensing potential of fruit, stem and leaves of Salvadora persica L. methanolic extracts. Microb Pathog 2017; 109: 169-76.
[http://dx.doi.org/10.1016/j.micpath.2017.05.036] [PMID: 28552808]
[59]
Jindal SK., Bhansali, R.R. Satyavir. Salvadora tree-A Potential Source of Non Edible Oil; Proceeding of All India Seminar on Rabi Oil seed crop. Jodhpur: CAZRI 1996.
[60]
Dogan AU. Bassanite from Salvadora persica: a new evaporitic biomineral carbonates and evaporates 2005; 20(1): 2-7.
[61]
Khalil A. Benzylamides from Salvadora persica. Arch Pharma Res 2006; 29(11): 952-6.
[62]
Kamil M. Pharmacognostical and phytochemical studies on S. Persica L. Hamdard Medicus 1999; 42: 64-75.
[63]
Darmani H, Al-Hiyasat AS, El betieha AM, Alkofahi A. The effect of an extract of Salvadora persica on fertility of male and female mice. Phytomedicine 2003; 0(1): 63-5.
[PMID: 12622466]
[64]
Abdel-Wahab SM, Selim MA. Investigation of the flavonoid content of Salvadora persica L. Bull. Fac. Pharm. Cairo Univ 1990; 28: 67-70.
[65]
Ray AB, Chand L, Dutta SC. Salvodourea. New urea derivative from Salvadora persica. Chem Ind 1975; 12: 517-8.
[66]
Al-Bagieh NH. Antiherpes simplex c-virus type 1 activity of benzyisothicyanate. Biom Lett 1990; 47: 67-70.
[67]
Al-Ayed MS, Asaad AM, Qureshi MA, Attia HG, AlMarrani AH. Antibacterial activity of Salvadora persica L. (miswak) extracts against multidrug resistant bacterial clinical isolates. Evid Based Complement Alternat Med 2016; 20167083964
[http://dx.doi.org/10.1155/2016/7083964] [PMID: 26904146]
[68]
Khalil MA, El-Sabbagh MS, El Naggar EB, El-Erian RH. Antibacterial activity of Salvadora persica against oral pathogenic bacterial isolates. Niger J Clin Pract 2019; 22(10): 1378-87.
[http://dx.doi.org/10.4103/njcp.njcp_413_14] [PMID: 31607727]
[69]
Abhary M, Al-Hazmi A-A. Antibacterial activity of Miswak (Salvadora persica L.) extracts on oral hygiene. J Taibah Univ Sci 2015.
[http://dx.doi.org/10.1016/j.jtusci.2015.09.007]
[70]
Ebrahim K, Mekonnen A. Studies on antioxidant and antimicrobial activities of Salvadora persica. Res J Med Plant 2018; 12: 26-32.
[http://dx.doi.org/10.3923/rjmp.2018.26.32]
[71]
Noumi E, Snoussi M, Hajlaoui H, Valentin E, Bakhrouf A. Antifungal properties of Salvadora persica and Juglans regia L. extracts against oral Candida strains. Eur J Clin Microbiol Infect Dis 2010; 29(1): 81-8.
[http://dx.doi.org/10.1007/s10096-009-0824-3] [PMID: 19899011]
[72]
Amna Ali Saddiq. Monagi H. Alkinani, Fungicidal impact of Salvadora persica L. (Miswak) extract on growth of foodborne pathogens, Aspergillus species, dose-response. Int J 2019. July-September: 1-5.
[73]
Ibrahim AY, El-Gengaihi SE, Motawea HM, Sleem AM. Anti-inflammatory activity of Salvadora persica L. against carrageenan induced paw oedema in rat relevant to inflammatory cytokines. Not Sci Biol 2011; 4(3): 22-8.
[http://dx.doi.org/10.15835/nsb346378]
[74]
Hoor T, Farooqui R, Shaikh JM, Karim N. Salvadora persica; anti-inflammatory activity in rats Professional Med J 2014; 21(1): 070-4.
[75]
Baba FK, Ranganayakulu. GS, Subramanyam P, Muralidhara Rao D. Anti-cancer and anti-inflammatory activity of Salvadora Persica L. Indo Am J Pharm Res 2018; 8(05): 1179-88.
[76]
Hooda MS, Pal R. Analgesic activity of crude hydro-alcoholic extract of Salvadora persica root. World J Pharm Res 2017; 6(11): 895-902.
[77]
Ahmad M, Imran H, Yaqeen Z, et al. Pharmacological profile of Salvadora persica. Pak J Pharm Sci 2011; 24(3): 323-30.
[PMID: 21715265]
[78]
Lebda MA, El-Far AH, Noreldin AE, Elewa YHA, Al Jaouni SK, Mousa SA. Protective effects of miswak (Salvadora persica) against experimentally induced gastric ulcers in rats. Oxid Med Cell Longev 2018; 2018: 6703296.
[http://dx.doi.org/10.1155/2018/6703296] [PMID: 30116487]
[79]
Monforte MT, Miceli N, Mondello MR, Sanogo R, Rossitto A, Galati EM. Antiulcer activity of Salvadora persica on experimental ASA-induced ulcer in rats: ultrastructural modifications. Pharm Biol 2001; 39(4): 289-92.
[http://dx.doi.org/10.1076/phbi.39.4.289.5918]
[80]
Monforte MT, Trovato A, Rossitto A, et al. Anticonvulsant and sedative effects of Salvadora persica L. stem extracts. Phytother Res 2002; 16(4): 395-7.
[http://dx.doi.org/10.1002/ptr.977] [PMID: 12112302]
[81]
Darmani H, Al-Hiyasat AS, Elbetieha AM, Alkofahi A. The effect of an extract of Salvadora persica (Meswak, chewing stick) on fertility of male and female mice. Phytomedicine 2003; 10(1): 63-5.
[http://dx.doi.org/10.1078/094471103321648683] [PMID: 12622466]
[82]
Al-Shaybany TN, Al-Dujaili AN, Al-Aredhi AJA. Effect of ethanolic extracts of Salvadora persica roots on female albino rats. J Pharm Biol Sci (New York) 2016; 7(6): 1115-25.
[83]
Pratima T, Minakshi N, Satish G. Antioxidant, antimicrobial and wound healing activity of salvadora persica twig extracts. J Complement Med Alt Healthcare 2018; 7(4)555720
[http://dx.doi.org/10.19080/JCMAH.2018.07.555720]
[84]
Imran H, Ahmad M, Rahman A, et al. Evaluation of wound healing effects between Salvadora persica ointment and Solcoseryl jelly in animal model. Pak J Pharm Sci 2015; 28(5): 1777-80.
[PMID: 26408876]
[85]
Dkhil MA, Thagfan FA, Hassan AS, Al-Shaebi EM, Abdel-Gaber R, Al-Quraishy S. Anthelmintic, anticoccidial and antioxidant activity of Salvadora persica root extracts. Saudi J Biol Sci 2019; 26(6): 1223-6.
[http://dx.doi.org/10.1016/j.sjbs.2019.02.006] [PMID: 31516352]
[86]
Abdul Majeed S. Anthelmintic activity of Salvadora persica root extract against Pheretima posthuma. Int J Pharm Sci Res 2011; 2(9): 2343-6.
[http://dx.doi.org/10.13040/IJPSR.0975-8232.2(9).2343-46]
[87]
Rabbani S. Ameliorative effect of Salvadora persica (Miswak) on cigarette smoke induced anxiety and depression in rats. Int J Pharm Investig 2020; 10(1): 32-6.
[http://dx.doi.org/10.5530/ijpi.2020.1.6]
[88]
Tahani H. Antidepressant effect of aqueous extract of Salvadora persica in mice. Arch Phar   Pharmacol Res 2020. 2(5): 1.
[89]
Huda M. Effect of Salvadora persica Linn root aqueous extract on oral epithelial dysplasia and oral cancer cell lines. Trop J Pharm Res 2019; 18(12): 2591-6.
[90]
Al-Dabbagh B, Elhaty IA, Murali C, Al Madhoon A, Amin A. Salvadora persica (Miswak): antioxidant and promising antiangiogenic insights. Am J Plant Sci 2018; 9: 1228-44.
[http://dx.doi.org/10.4236/ajps.2018.96091]
[91]
Miri A, Sarani M. Biosynthesis and cytotoxic study of synthesized zinc oxide nanoparticles using Salvadora persica. Bionanoscience 2019; 9: 164-71.
[http://dx.doi.org/10.1007/s12668-018-0579-3]
[92]
El-Desoukya SK, Hawas UW, Khemira H, Kim Y-K. Salvastearolide, a new acyl-glyceride, and other constituents from the seeds of Salvadora persica. Rev Bras Farmacogn 2018; 28: 564-7.
[http://dx.doi.org/10.1016/j.bjp.2018.05.013]
[93]
Amjed S, Junaid K, Jafar J, et al. Detection of antibacterial activities of Miswak, Kalonji and Aloe vera against oral pathogens & anti-proliferative activity against cancer cell line. BMC Complement Altern Med 2017; 17(1): 265.
[http://dx.doi.org/10.1186/s12906-017-1778-0] [PMID: 28506259]
[94]
Al-sieni Abdulbasit II. The antibacterial activity of traditionally used Salvadora persica L. (miswak) and commiphora gileadensis (palsam) in Saudi Arabia Afr J Tradit Complement Altern Med 2014; 11(1): 23-7.
[95]
Iyer D, Patil UK. Evaluation of antihyperlipidemic and antitumor activities of isolated coumarins from Salvadora indica. Pharm Biol 2014; 52(1): 78-85.
[96]
Deepa Iyer. Efficacy of stigmast-5-en-3β-ol isolated from Salvadora persica L. as antihyperlipidemic and antitumor agent: evidence from animal studies. Asian Pac J Trop Dis 2012; S849-55.
[97]
Ibrahim , et al. Phytochemical and cytotoxicity investigations of Salvadora persica bark extracts. JASMR 2011; 6(2): 127-33.
[98]
Kumar D, Sharma PK. Extraction and evaluation of Salvadora persica bark extract for its antioxidant and antimicrobial activity. Biosc Biotech Res Comm 2020. 13(2): 1.

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    36 statements were executed, 4 of which were duplicates, 32 unique. Show only duplicated121ms
    • Connection Establishedalphaeurekaselec_live_10_06_2022UserAccessCheck.php#24
      Backtrace
      • 9. middleware::check_user_access:24
      • 10. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
      • 11. vendor/laravel/framework/src/Illuminate/Routing/Middleware/SubstituteBindings.php:50
      • 12. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
      • 13. vendor/laravel/framework/src/Illuminate/Foundation/Http/Middleware/VerifyCsrfToken.php:88
    • INSERT INTO visitor_ip_address (ip_address,visitor_agent,visitor_count, created_on,updated_on) VALUES ('51408323','',1,1739971322,1739971322) ON DUPLICATE KEY UPDATE visitor_count=visitor_count + 1, updated_on=1739971322
      2.45msalphaeurekaselec_live_10_06_2022UserAccessCheck.php#24
      Backtrace
      • 11. middleware::check_user_access:24
      • 12. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
      • 13. vendor/laravel/framework/src/Illuminate/Routing/Middleware/SubstituteBindings.php:50
      • 14. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
      • 15. vendor/laravel/framework/src/Illuminate/Foundation/Http/Middleware/VerifyCsrfToken.php:88
    • INSERT INTO visitor_ip_address_detail (ip_address,visitor_url,visitor_count, created_on,updated_on) VALUES ('51408323','/article/108954',1,1739971322,1739971322)
      250μsalphaeurekaselec_live_10_06_2022UserAccessCheck.php#27
      Backtrace
      • 11. middleware::check_user_access:27
      • 12. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
      • 13. vendor/laravel/framework/src/Illuminate/Routing/Middleware/SubstituteBindings.php:50
      • 14. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
      • 15. vendor/laravel/framework/src/Illuminate/Foundation/Http/Middleware/VerifyCsrfToken.php:88
    • (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_journal_volume_trail WHERE to_ip >= 51408323 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 51408323) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_journal_volume_corporate WHERE to_ip >= 51408323 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 51408323) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_journal_volume_token WHERE to_ip >= 51408323 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 51408323) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_ebook_volume_trail WHERE to_ip >= 51408323 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 51408323) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_ebook_volume_corporate WHERE to_ip >= 51408323 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 51408323) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_ebook_volume_token WHERE to_ip >= 51408323 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 51408323) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_issue_trail WHERE to_ip >= 51408323 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 51408323) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_issue_corporate WHERE to_ip >= 51408323 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 51408323) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_issue_token WHERE to_ip >= 51408323 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 51408323) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_article_trail WHERE to_ip >= 51408323 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 51408323) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_article_corporate WHERE to_ip >= 51408323 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 51408323) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_article_token WHERE to_ip >= 51408323 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 51408323) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_chapter_trail WHERE to_ip >= 51408323 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 51408323) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_chapter_corporate WHERE to_ip >= 51408323 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 51408323) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_chapter_token WHERE to_ip >= 51408323 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 51408323) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_disease_corporate WHERE to_ip >= 51408323 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 51408323) limit 1
      19.5msalphaeurekaselec_live_10_06_2022UserAccess.php#784
      Bindings
      • 0: 51408323
      • 1: 51408323
      • 2: 51408323
      • 3: 51408323
      • 4: 51408323
      • 5: 51408323
      • 6: 51408323
      • 7: 51408323
      • 8: 51408323
      • 9: 51408323
      • 10: 51408323
      • 11: 51408323
      • 12: 51408323
      • 13: 51408323
      • 14: 51408323
      • 15: 51408323
      Backtrace
      • 14. app/Models/UserAccess/UserAccess.php:784
      • 15. middleware::check_user_access:114
      • 16. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Middleware/SubstituteBindings.php:50
      • 18. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
    • SELECT at.type_name, p.copyright, p.publisher_location,m.month,y.year, a.publish_on, a.nid article_nid,a.article_id, a.pmid, a.issue_id, a.title, a.abstract,a.podcast,a.altmetric_score,a.altmetric_url,a.kudos_url, a.page_count, a.first_page, a.elocator, a.last_page, i.publication_date, a.file_name, a.file_path, a.doi, a.is_epub,a.epub_type, a.volume_id, a.is_uploaded, a.editor_choice, a.is_epub, j.image_file_name, a.article_no, a.art_type AS article_type, a.supplementary_filename,a.html_filename,a.prc_filename,a.epub_filename, a.graph_abs_lg_filename, a.graph_abs_sm_filename, a.oa_image_lg_filename, a.oa_image_sm_filename, j.journal_banner,a.animated_abstract,a.erratum_in,a.erratum_for, (CASE WHEN a.issue_id =0 THEN j.epub_price ELSE j.price END) AS sell_price, j.epub_price, j.nid AS jour_nid, j.title AS journal_title, j.issn, j.eissn,j.journal_id, j.subtitle AS jour_subtitle, v.volume_id,v.volume_name AS volume, v.year_id, i.title AS issue, i.month_id ,i.type issue_type, j.subtitle,j.formerly_title, ac.subtitle AS epub_title,a.crossmark_enabled,a.text_mining_urls,a.license_urls,a.created, a.receivedate, a.revisedate, a.acceptdate,js.js_title FROM article a LEFT JOIN article_section ac ON a.is_epub = ac.art_sec_id LEFT JOIN journal_section js ON a.js_id = js.js_id LEFT JOIN article_type at ON a.art_type = at.art_type_id LEFT JOIN issue i ON a.issue_id = i.issue_id LEFT JOIN month m ON m.id = i.month_id LEFT JOIN volume v ON v.volume_id = a.volume_id INNER JOIN year y ON y.id = v.year_id INNER JOIN journal j ON j.journal_id = a.journal_id INNER JOIN publisher p ON p.publisher_id = j.publisher_id WHERE a.article_id=108954
      1.11msalphaeurekaselec_live_10_06_2022Article.php#408
      Backtrace
      • 11. app/Models/Article.php:408
      • 12. app/Http/Controllers/ArticleController.php:2515
      • 13. app/Http/Controllers/ArticleController.php:2035
      • 14. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 15. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
    • select * from `journal` where `journal_id` = 35 limit 1
      1.16msalphaeurekaselec_live_10_06_2022Journal.php#64
      Bindings
      • 0: 35
      Backtrace
      • 14. app/Models/Journal.php:64
      • 15. app/Http/Controllers/ArticleController.php:2516
      • 16. app/Http/Controllers/ArticleController.php:2035
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 18. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
    • select count(*) as aggregate from (select j.nid as journal_nid,j.flyer_link,j.title ,j.issn,j.eissn,j.keyword, j.journal_id as journal_id, j.subtitle, j.image_file_name,j.description,j.journal_insight_url,j.doi from `subject_journal` as `sj` inner join `journal` as `j` on `j`.`journal_id` = `sj`.`journal_id` where j.journal_status=1 and subject_id IN (SELECT subject_id FROM subject_journal WHERE journal_id=35) and sj.journal_id!=35 group by `j`.`nid`) as `aggregate_table`
      790μsalphaeurekaselec_live_10_06_2022Subject.php#200
      Backtrace
      • 16. app/Models/Subject.php:200
      • 17. app/Http/Controllers/ArticleController.php:2517
      • 18. app/Http/Controllers/ArticleController.php:2035
      • 19. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 20. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
    • select j.nid as journal_nid,j.flyer_link,j.title ,j.issn,j.eissn,j.keyword, j.journal_id as journal_id, j.subtitle, j.image_file_name,j.description,j.journal_insight_url,j.doi from `subject_journal` as `sj` inner join `journal` as `j` on `j`.`journal_id` = `sj`.`journal_id` where j.journal_status=1 and subject_id IN (SELECT subject_id FROM subject_journal WHERE journal_id=35) and sj.journal_id!=35 group by `j`.`nid` order by `j`.`journal_id` asc limit 10 offset 0
      690μsalphaeurekaselec_live_10_06_2022Subject.php#200
      Backtrace
      • 14. app/Models/Subject.php:200
      • 15. app/Http/Controllers/ArticleController.php:2517
      • 16. app/Http/Controllers/ArticleController.php:2035
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 18. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
    • select count(*) as aggregate from (select v.nid as volume_id,e.nid,e.title,v.issn,v.eissn,v.isbn,v.eisbn,e.ebook_id, v.image_file_name,v.file_path,v.flyer_link,v.ebook_volume_id, v.volume_name,v.doi,v.year_id,v.introduction from `subject_ebook` as `se` inner join `ebook` as `e` on `e`.`ebook_id` = `se`.`ebook_id` inner join `ebook_volume` as `v` on `v`.`ebook_id` = `se`.`ebook_id` inner join `year` as `y` on `y`.`id` = `v`.`year_id` where subject_id IN (SELECT subject_id FROM subject_journal WHERE journal_id=35) and v.ebook_status='1' and y.year > 2020 group by `v`.`nid`) as `aggregate_table`
      1.18msalphaeurekaselec_live_10_06_2022Subject.php#220
      Backtrace
      • 16. app/Models/Subject.php:220
      • 17. app/Http/Controllers/ArticleController.php:2518
      • 18. app/Http/Controllers/ArticleController.php:2035
      • 19. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 20. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
    • select v.nid as volume_id,e.nid,e.title,v.issn,v.eissn,v.isbn,v.eisbn,e.ebook_id, v.image_file_name,v.file_path,v.flyer_link,v.ebook_volume_id, v.volume_name,v.doi,v.year_id,v.introduction from `subject_ebook` as `se` inner join `ebook` as `e` on `e`.`ebook_id` = `se`.`ebook_id` inner join `ebook_volume` as `v` on `v`.`ebook_id` = `se`.`ebook_id` inner join `year` as `y` on `y`.`id` = `v`.`year_id` where subject_id IN (SELECT subject_id FROM subject_journal WHERE journal_id=35) and v.ebook_status='1' and y.year > 2020 group by `v`.`nid` order by `v`.`ebook_volume_id` desc limit 10 offset 0
      1.11msalphaeurekaselec_live_10_06_2022Subject.php#220
      Backtrace
      • 14. app/Models/Subject.php:220
      • 15. app/Http/Controllers/ArticleController.php:2518
      • 16. app/Http/Controllers/ArticleController.php:2035
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 18. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
    • select * from `keywords` where `article_id` = '108954'
      3.16msalphaeurekaselec_live_10_06_2022Keywords.php#43
      Bindings
      • 0: 108954
      Backtrace
      • 13. app/Models/Keywords.php:43
      • 14. app/Http/Controllers/ArticleController.php:2519
      • 15. app/Http/Controllers/ArticleController.php:2035
      • 16. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 17. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
    • select * from `article_citation` where `article_id` = '108954'
      3.43msalphaeurekaselec_live_10_06_2022Article.php#1570
      Bindings
      • 0: 108954
      Backtrace
      • 13. app/Models/Article.php:1570
      • 14. app/Http/Controllers/ArticleController.php:2520
      • 15. app/Http/Controllers/ArticleController.php:2035
      • 16. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 17. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
    • select CONCAT_WS(' ',au.first_name, ' ', ifnull(au.initials,''), ' ', au.last_name) as authors, CONCAT(au.last_name, IFNULL(CONCAT(' ', au.initials), ''), ' ', au.first_name) AS authorsRIS, CONCAT_WS(' ',au.last_name, ' ', ifnull(au.initials,''), ' ', au.first_name) as authorsCiteAs, CONCAT_WS(' ',au.first_name, IFNULL(CONCAT(' ', au.initials), ''), IFNULL(CONCAT(' ', au.last_name), '')) as authorsmodal , `au`.*, `af`.`ror_id`, `af`.`institution`, `af`.`department`, `af`.`country`, `af`.`city`, `af`.`address`, (GROUP_CONCAT(TRIM(BOTH ', ' FROM CONCAT(ifnull(concat(af.institution,','),''), ifnull(concat(af.department,','),''), ifnull(concat(af.address,','),''), ifnull(concat(af.city,','),''), ifnull(concat(af.country,','),''), ifnull(concat(af.postal_code,','),''), ifnull(concat(af.phone,','),''), ifnull(concat(af.fax,','),''))) SEPARATOR '|')) as `author_affiliation`, (GROUP_CONCAT(TRIM(BOTH ', ' FROM CONCAT(ifnull(concat(af.web_view,','),''))) SEPARATOR '|')) as `web_view` from `author` as `au` left join `author_affiliation` as `af` on `au`.`author_id` = `af`.`author_id` where `au`.`article_id` = '108954' group by `au`.`author_id` order by `au`.`article_id` asc, `au`.`sequence` asc
      2.75msalphaeurekaselec_live_10_06_2022Author.php#86
      Bindings
      • 0: 108954
      Backtrace
      • 13. app/Models/Author.php:86
      • 14. app/Http/Controllers/ArticleController.php:2533
      • 15. app/Http/Controllers/ArticleController.php:2035
      • 16. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 17. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
    • select `bo`.* from `bundle_offer` as `bo` where `bo`.`bundle_status` = 'A' order by `bo`.`bundle_id` desc
      330μsalphaeurekaselec_live_10_06_2022BundleOffer.php#57
      Bindings
      • 0: A
      Backtrace
      • 13. app/Models/BundleOffer.php:57
      • 14. app/Http/Controllers/ArticleController.php:2535
      • 15. app/Http/Controllers/ArticleController.php:2035
      • 16. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 17. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
    • select `subtitle` from `journal` where `continues_publication_journal` = 1
      770μsalphaeurekaselec_live_10_06_2022Article.php#1960
      Bindings
      • 0: 1
      Backtrace
      • 13. app/Models/Article.php:1960
      • 14. app/Http/Controllers/ArticleController.php:2062
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • Select j.subtitle, v.volume_id as volume_id,v.year_id,y.year as year,v.volume_name, v.total_no_of_issues, i.issue_id as issue_id,i.title as issue, i.publication_date as issue_pub_date from journal j join volume v on j.journal_id = v.journal_id join issue i on v.volume_id = i.volume_id join article a on a.issue_id = i.issue_id join year y on v.year_id = y.id where j.journal_id = 35 and i.is_uploaded = 1 order by v.volume_name+0 desc, i.title+0 desc limit 1
      47.8msalphaeurekaselec_live_10_06_2022Issue.php#298
      Backtrace
      • 11. app/Models/Issue.php:298
      • 12. app/Http/Controllers/ArticleController.php:2068
      • 13. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 14. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select a.nid,a.publish_on, a.pmid,a.article_id,a.doi,j.journal_id,j.subtitle,v.volume_name,a.volume_id as volume_id, a.issue_id,a.title,first_page, last_page, page_count,abstract,ifnull(is_abstract,"y"),asec.title as article_section,at.type_name as article_type_name, a.article_id as ArticleID ,is_epub,epub_price,epub_type,a.created, y.year from `article` as `a` left join `article_section` as `asec` on `asec`.`art_sec_id` = `a`.`is_epub` left join `article_type` as `at` on `at`.`art_type_id` = `a`.`art_type` left join `journal` as `j` on `j`.`journal_id` = `a`.`journal_id` inner join `volume` as `v` on `a`.`volume_id` = `v`.`volume_id` inner join `year` as `y` on `v`.`year_id` = `y`.`id` where a.article_status != "W" and a.is_epub = 1 and a.journal_id = 35 and a.is_uploaded = 1 group by `a`.`article_id` order by `a`.`publish_on` desc
      9.65msalphaeurekaselec_live_10_06_2022Article.php#528
      Backtrace
      • 13. app/Models/Article.php:528
      • 14. app/Http/Controllers/ArticleController.php:2070
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select a.nid,a.publish_on, a.pmid,a.article_id,a.doi,j.journal_id,j.subtitle,v.volume_name,a.volume_id as volume_id, a.issue_id,a.title,first_page, last_page, page_count,abstract,ifnull(is_abstract,"y"),asec.title as article_section,at.type_name as article_type_name, a.article_id as ArticleID ,is_epub,epub_price,epub_type,a.created, y.year from `article` as `a` left join `article_section` as `asec` on `asec`.`art_sec_id` = `a`.`is_epub` left join `article_type` as `at` on `at`.`art_type_id` = `a`.`art_type` left join `journal` as `j` on `j`.`journal_id` = `a`.`journal_id` inner join `volume` as `v` on `a`.`volume_id` = `v`.`volume_id` inner join `year` as `y` on `v`.`year_id` = `y`.`id` where a.article_status != "W" and a.is_epub = 4 and a.journal_id = 35 and a.is_uploaded = 1 group by `a`.`article_id` order by `a`.`publish_on` desc
      8.31msalphaeurekaselec_live_10_06_2022Article.php#528
      Backtrace
      • 13. app/Models/Article.php:528
      • 14. app/Http/Controllers/ArticleController.php:2071
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select pdf, html, epub, prc from `article_metrics` where `article_id` = 108954 limit 1
      250μsalphaeurekaselec_live_10_06_2022Article.php#744
      Bindings
      • 0: 108954
      Backtrace
      • 14. app/Models/Article.php:744
      • 15. app/Http/Controllers/ArticleController.php:2091
      • 16. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 17. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 18. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select * from content_by_diseases where content_id = 108954 and content_type = 'article' order by status desc limit 1
      290μsalphaeurekaselec_live_10_06_2022Article.php#751
      Backtrace
      • 11. app/Models/Article.php:751
      • 12. app/Http/Controllers/ArticleController.php:2094
      • 13. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 14. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select * from `node_meta` where `nid` = 184666 limit 1
      230μsalphaeurekaselec_live_10_06_2022Meta.php#30
      Bindings
      • 0: 184666
      Backtrace
      • 14. app/Models/Meta.php:30
      • 15. app/Http/Controllers/ArticleController.php:2101
      • 16. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 17. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 18. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select `bo`.* from `bundle_offer` as `bo` where `bo`.`bundle_status` = 'A' order by `bo`.`bundle_id` desc
      280μsalphaeurekaselec_live_10_06_2022BundleOffer.php#57
      Bindings
      • 0: A
      Backtrace
      • 13. app/Models/BundleOffer.php:57
      • 14. app/Http/Controllers/ArticleController.php:2108
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select * from `tbl_ht_submission` as `h` where `h`.`subtitle` = 'CNF' and (h.proposal_closing_date = 0 OR TO_DAYS(FROM_UNIXTIME(h.proposal_closing_date)) >= TO_DAYS(NOW())) order by `h`.`manuscript` asc
      380μsalphaeurekaselec_live_10_06_2022Article.php#2025
      Bindings
      • 0: CNF
      Backtrace
      • 13. app/Models/Article.php:2025
      • 14. app/Http/Controllers/ArticleController.php:2112
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select count(*) as total_count, content_type_access_id as access_type from journal_access where content_type_id = '108954' and content_type = 'a' and ( (from_date <= CURDATE() and to_date >= CURDATE() and perpetual= 0) or (from_date is null and to_date is null and perpetual= 1) )
      470μsalphaeurekaselec_live_10_06_2022ContentAccess.php#647
      Backtrace
      • 11. app/Models/ContentAccess.php:647
      • 12. app/Http/Controllers/ArticleController.php:2186
      • 13. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 14. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select count(*) as total_count, content_type_access_id as access_type from journal_access where content_type_id = '10425' and content_type = 'i' and ( (from_date <= CURDATE() and to_date >= CURDATE() and perpetual= 0) or (from_date is null and to_date is null and perpetual= 1) )
      400μsalphaeurekaselec_live_10_06_2022ContentAccess.php#647
      Backtrace
      • 11. app/Models/ContentAccess.php:647
      • 12. app/Http/Controllers/ArticleController.php:2207
      • 13. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 14. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select count(*) as total_count, content_type_access_id as access_type from journal_access where content_type_id = '2945' and content_type = 'v' and ( (from_date <= CURDATE() and to_date >= CURDATE() and perpetual= 0) or (from_date is null and to_date is null and perpetual= 1) )
      380μsalphaeurekaselec_live_10_06_2022ContentAccess.php#647
      Backtrace
      • 11. app/Models/ContentAccess.php:647
      • 12. app/Http/Controllers/ArticleController.php:2231
      • 13. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 14. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Trial Access" as access_base_text, CASE j.type WHEN 111 THEN true ELSE false END as terms_popup, "S" as content_download_type, null as restricted_user_access_key, null as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"volume" as access_level,"" as issue_id,"" as article_id from `user_access_journal_volume_trail` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 51408323 and j.to_ip >=51408323 )) and ((j.from_date <= 1739971322 and j.to_date >= 1739971322 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.volume_id = 2945) union (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Subscribed" as access_base_text, false as terms_popup, "S" as content_download_type, null as restricted_user_access_key, null as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"volume" as access_level,"" as issue_id,"" as article_id from `user_access_journal_volume_corporate` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 51408323 and j.to_ip >=51408323 )) and ((j.from_date <= 1739971322 and j.to_date >= 1739971322 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.volume_id = 2945) union (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Token Based Access" as access_base_text, false as terms_popup, "R" as content_download_type, j.uc_id as restricted_user_access_key, "v" as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"volume" as access_level,"" as issue_id,"" as article_id from `user_access_journal_volume_token` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 51408323 and j.to_ip >=51408323 )) and ((j.from_date <= 1739971322 and j.to_date >= 1739971322 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.volume_id = 2945)
      4.68msalphaeurekaselec_live_10_06_2022UserAccess.php#1266
      Backtrace
      • 13. app/Models/UserAccess/UserAccess.php:1266
      • 14. app/Http/Controllers/ArticleController.php:2272
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Trial Access" as access_base_text, CASE j.type WHEN 111 THEN true ELSE false END as terms_popup, "S" as content_download_type, null as restricted_user_access_key, null as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"issue" as access_level,j.issue_id,"" as article_id from `user_access_issue_trail` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 51408323 and j.to_ip >=51408323 )) and ((j.from_date <= 1739971322 and j.to_date >= 1739971322 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.issue_id = 10425) union (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Subscribed" as access_base_text, false as terms_popup, "S" as content_download_type, null as restricted_user_access_key, null as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"issue" as access_level,j.issue_id,"" as article_id from `user_access_issue_corporate` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 51408323 and j.to_ip >=51408323 )) and ((j.from_date <= 1739971322 and j.to_date >= 1739971322 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.issue_id = 10425) union (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Token Based Access" as access_base_text, false as terms_popup, "R" as content_download_type, j.uc_id as restricted_user_access_key, "v" as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"issue" as access_level,j.issue_id,"" as article_id from `user_access_issue_token` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 51408323 and j.to_ip >=51408323 )) and ((j.from_date <= 1739971322 and j.to_date >= 1739971322 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.issue_id = 10425)
      800μsalphaeurekaselec_live_10_06_2022UserAccess.php#1266
      Backtrace
      • 13. app/Models/UserAccess/UserAccess.php:1266
      • 14. app/Http/Controllers/ArticleController.php:2297
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Trial Access" as access_base_text, CASE j.type WHEN 111 THEN true ELSE false END as terms_popup, "S" as content_download_type, null as restricted_user_access_key, null as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"article" as access_level, j.issue_id, j.article_id from `user_access_article_trail` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 51408323 and j.to_ip >=51408323 )) and ((j.from_date <= 1739971322 and j.to_date >= 1739971322 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.article_id = 108954) union (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Subscribed" as access_base_text, false as terms_popup, "S" as content_download_type, null as restricted_user_access_key, null as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"article" as access_level, j.issue_id, j.article_id from `user_access_article_corporate` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 51408323 and j.to_ip >=51408323 )) and ((j.from_date <= 1739971322 and j.to_date >= 1739971322 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.article_id = 108954) union (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Token Based Access" as access_base_text, false as terms_popup, "R" as content_download_type, j.uc_id as restricted_user_access_key, "v" as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"article" as access_level, j.issue_id, j.article_id from `user_access_article_token` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 51408323 and j.to_ip >=51408323 )) and ((j.from_date <= 1739971322 and j.to_date >= 1739971322 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.article_id = 108954)
      820μsalphaeurekaselec_live_10_06_2022UserAccess.php#1266
      Backtrace
      • 13. app/Models/UserAccess/UserAccess.php:1266
      • 14. app/Http/Controllers/ArticleController.php:2329
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select * from `article` where `first_page` < '302' and is_uploaded = 1 and issue_id = 10425 order by cast(first_page as SIGNED) desc limit 1
      540μsalphaeurekaselec_live_10_06_2022Article.php#1819
      Bindings
      • 0: 302
      Backtrace
      • 14. app/Models/Article.php:1819
      • 15. app/Http/Controllers/ArticleController.php:2470
      • 16. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 17. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 18. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select * from `article` where `last_page` > '309' and is_uploaded = 1 and issue_id = 10425 order by cast(first_page as SIGNED) asc limit 1
      450μsalphaeurekaselec_live_10_06_2022Article.php#1831
      Bindings
      • 0: 309
      Backtrace
      • 14. app/Models/Article.php:1831
      • 15. app/Http/Controllers/ArticleController.php:2472
      • 16. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 17. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 18. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select `language_id` from `multilanguage` where `short_code` = 'en'
      180μsalphaeurekaselec_live_10_06_2022ArticleController.php#2497
      Bindings
      • 0: en
      Backtrace
      • 14. app/Http/Controllers/ArticleController.php:2497
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • 18. vendor/laravel/framework/src/Illuminate/Routing/Route.php:206
    • select `source_lang_label`, `target_lang_label` from `multilanguage_labels` where `target_lang_id` = 1
      240μsalphaeurekaselec_live_10_06_2022MultiLanguage.php#23
      Bindings
      • 0: 1
      Backtrace
      • 13. app/Models/MultiLanguage.php:23
      • 14. app/Http/Controllers/ArticleController.php:2498
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select `id` from `multilanguage_article` where `article_id` = 108954 limit 1
      2.47msalphaeurekaselec_live_10_06_2022ArticleController.php#2506
      Bindings
      • 0: 108954
      Backtrace
      • 16. app/Http/Controllers/ArticleController.php:2506
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 18. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 19. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • 20. vendor/laravel/framework/src/Illuminate/Routing/Route.php:206
    • select b.banner_link, b.banner_name, b.banner_script, b.banner_remarks, b.banner_file_name, b.banner_placement, bd.content_type, bd.content_id from `tbl_banner` as `b` inner join `tbl_banner_detail` as `bd` on `bd`.`banner_id` = `b`.`banner_id` inner join `users` as `u` on `u`.`id` = `b`.`updated_by` inner join `journal` as `j` on `j`.`journal_id` = `bd`.`content_id` where `b`.`banner_journal` = 1 and `bd`.`content_type` = 'J' and `bd`.`content_id` = 35 and `b`.`banner_from_date` <= 1739971322 and `b`.`banner_to_date` >= 1739971322 and `b`.`banner_status` = 'A' order by `b`.`banner_id` desc
      1.58msalphaeurekaselec_live_10_06_2022Banner.php#95
      Bindings
      • 0: 1
      • 1: J
      • 2: 35
      • 3: 1739971322
      • 4: 1739971322
      • 5: A
      Backtrace
      • 13. app/Models/Banner.php:95
      • 14. app/Http/helpers.php:404
      • 17. vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • 18. vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • 19. vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:73
    • select b.banner_link, b.banner_name, b.banner_script, b.banner_remarks, b.banner_file_name, b.banner_placement, bd.content_type, bd.content_id from `tbl_banner` as `b` inner join `tbl_banner_detail` as `bd` on `bd`.`banner_id` = `b`.`banner_id` inner join `users` as `u` on `u`.`id` = `b`.`updated_by` inner join `journal` as `j` on `j`.`journal_id` = `bd`.`content_id` where `b`.`banner_journal` = 1 and `bd`.`content_type` = 'J' and `bd`.`content_id` = 35 and `b`.`banner_from_date` <= 1739971322 and `b`.`banner_to_date` >= 1739971322 and `b`.`banner_status` = 'A' order by `b`.`banner_id` desc
      1.48msalphaeurekaselec_live_10_06_2022Banner.php#95
      Bindings
      • 0: 1
      • 1: J
      • 2: 35
      • 3: 1739971322
      • 4: 1739971322
      • 5: A
      Backtrace
      • 13. app/Models/Banner.php:95
      • 14. app/Http/helpers.php:404
      • 17. vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • 18. vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • 19. vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:73
    • select count(*) as aggregate from `uc_cart_products` where cart_id='d11f32dc904849b28c5c6ed3a8c77dee'
      300μsalphaeurekaselec_live_10_06_2022Cart.php#271
      Backtrace
      • 15. app/Models/Cart.php:271
      • 16. view::layouts._header:260
      • 18. vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • 19. vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • 20. vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:73
    App\Models\MultiLanguage
    1MultiLanguage.php#?
        _token
        NKt2pDlKs07uYQT3YromudXcbjxPu5pOFKh0JouV
        uc_cart_id
        d11f32dc904849b28c5c6ed3a8c77dee
        _previous
        array:1 [ "url" => "http://alpha.eurekaselect.com/article/108954" ]
        _flash
        array:2 [ "old" => [] "new" => [] ]
        PHPDEBUGBAR_STACK_DATA
        []
        path_info
        /article/108954
        status_code
        200
        
        status_text
        OK
        format
        html
        content_type
        text/html; charset=UTF-8
        request_query
        []
        
        request_request
        []
        
        request_headers
        0 of 0
        array:9 [ "cookie" => array:1 [ 0 => "wayfindertarget=eyJpdiI6IjhyZ1RUZW91QndaaU1wWTZlN041RUE9PSIsInZhbHVlIjoiTnZqeGQvVHArTkhqbkozYkRreUMyck9HVjIwYjRKbWRVMHZYLzlZdWFQWT0iLCJtYWMiOiJlZWIyMTBhZTI2OGUzODBjZTA0NWI4ZTkwY2Y1NTQ0ZGYyNDUwNjBhZDY2MjgxNTM2YjhjYWE0NWQzOGM5ZDAzIiwidGFnIjoiIn0%3Dwayfindertarget=eyJpdiI6IjhyZ1RUZW91QndaaU1wWTZlN041RUE9PSIsInZhbHVlIjoiTnZqeGQvVHArTkhqbkozYkRreUMyck9HVjIwYjRKbWRVMHZYLzlZdWFQWT0iLCJtYWMiOiJlZWIyMTBhZTI2OGUz" ] "accept-encoding" => array:1 [ 0 => "gzip, deflate" ] "accept" => array:1 [ 0 => "text/html,application/xhtml+xml,application/xml;q=0.9,image/avif,image/webp,image/apng,*/*;q=0.8,application/signed-exchange;v=b3;q=0.7" ] "user-agent" => array:1 [ 0 => "Mozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; +claudebot@anthropic.com)" ] "upgrade-insecure-requests" => array:1 [ 0 => "1" ] "cache-control" => array:1 [ 0 => "no-cache" ] "pragma" => array:1 [ 0 => "no-cache" ] "connection" => array:1 [ 0 => "keep-alive" ] "host" => array:1 [ 0 => "alpha.eurekaselect.com" ] ]
        request_cookies
        0 of 0
        array:1 [ "wayfindertarget" => null ]
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