Abstract
Zinc oxide (ZnO) is a metal oxide well known for its photocatalytic property and is widely used in cosmetics. Lately, it has gained more importance in its biomedical applications, especially in cancer therapy. Scientific works have elucidated the efficiency of ZnO nanoparticles (NPs) against different cancer cell lines. There are safety concerns related to the usage of ZnO NPs as the zinc ion concentration may lead to changes in the human body. This review covers the significant pharmaceutical and biological aspects of ZnO NPs. Besides, this review updates ZnO NPs revolutionary use in photodynamic therapy (PDT), where it can work wonders and pave the way for novel therapeutic approaches against cancer.
Keywords: Zinc oxide, nanoparticles, cytotoxicity, photodynamic therapy, surface modification, cancer cell lines.
Graphical Abstract
Nanoscience & Nanotechnology-Asia
Title:Zinc Oxide Nanoparticles: A Biological and Pharmaceutical Review
Volume: 11 Issue: 6
Author(s): Behin Sundara Raj*Punitha Isaac Samraj
Affiliation:
- School of Pharmacy and Biomedical Sciences, Curtin University, Bentley, Perth, 6102,Australia
Keywords: Zinc oxide, nanoparticles, cytotoxicity, photodynamic therapy, surface modification, cancer cell lines.
Abstract: Zinc oxide (ZnO) is a metal oxide well known for its photocatalytic property and is widely used in cosmetics. Lately, it has gained more importance in its biomedical applications, especially in cancer therapy. Scientific works have elucidated the efficiency of ZnO nanoparticles (NPs) against different cancer cell lines. There are safety concerns related to the usage of ZnO NPs as the zinc ion concentration may lead to changes in the human body. This review covers the significant pharmaceutical and biological aspects of ZnO NPs. Besides, this review updates ZnO NPs revolutionary use in photodynamic therapy (PDT), where it can work wonders and pave the way for novel therapeutic approaches against cancer.
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Cite this article as:
Raj Sundara Behin *, Samraj Isaac Punitha, Zinc Oxide Nanoparticles: A Biological and Pharmaceutical Review, Nanoscience & Nanotechnology-Asia 2021; 11 (6) : e070820184647 . https://dx.doi.org/10.2174/2210681210999200807150739
DOI https://dx.doi.org/10.2174/2210681210999200807150739 |
Print ISSN 2210-6812 |
Publisher Name Bentham Science Publisher |
Online ISSN 2210-6820 |
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