摘要
天然聚合物，特别是多糖，已经用作各种治疗剂的药物递送系统，所述治疗剂例如肽，蛋白质，疫苗，DNA以及用于肠胃外和非肠胃外给药的药物。 壳聚糖是仅次于纤维素的天然含量第二高的多糖，是一种生物相容性和可生物降解的粘膜粘附性聚合物，已广泛用于制备纳米颗粒（NP）。 发现载有药物的壳聚糖NP稳定，可渗透且具有生物活性。 在这篇综述中，阐明了壳聚糖及其衍生物在药物递送中的重要性，讨论了壳聚糖和壳聚糖衍生物NPs的不同制备方法及其理化性质。 此外，还清楚地探索了成功的基于NP的药物递送系统的理想特性，以及这些NP的药物应用。
关键词: 壳聚糖，药物递送，离子凝胶化，乳化，去溶剂化，纳米颗粒。
图形摘要
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