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ISSN (Print): 1570-193X
ISSN (Online): 1875-6298

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General Review Article

Diverse Routes for the Synthesis of Indole-Fused Complex Architecture from Simple Molecules

Author(s): Shivendra Singh, Suresh Singh Chauhan, Neeraj Kumar Sharma, Sunil Dutt and Keshav Lalit Ameta*

Volume 18, Issue 2, 2021

Published on: 21 May, 2020

Page: [237 - 258] Pages: 22

DOI: 10.2174/1570193X17999200521101255

Price: $65

Abstract

Several easy, efficient and convenient procedures to access indoles fused heterocyclic systems are described in this review. These heterocyclic systems were synthesized from several cyclic or acyclic molecules via a variety of reactions such as Diels-Alder reaction, Michael addition, Morita- Baylis-Hillmann reaction and many other domino/Cascade approaches with high selectivity. Most of the given protocols in this review proceed through organocatalytic pathways; however, some underwent different catalytic and non-catalytic reactions.

Keywords: Analgesic, domino approach, indole heterocycles, multicomponent reactions, nootropic agents, organocatalysis, psychoanaleptic.

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Graphical Abstract

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