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Current Pharmaceutical Design

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ISSN (Print): 1381-6128
ISSN (Online): 1873-4286

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General Review Article

Curcumin for the Management of Periodontal Diseases: A Review

Author(s): Fatemeh Forouzanfar, Ali Forouzanfar, Thozhukat Sathyapalan, Hossein M. Orafai and Amirhossein Sahebkar*

Volume 26, Issue 34, 2020

Page: [4277 - 4284] Pages: 8

DOI: 10.2174/1381612826666200513112607

Price: $65

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Abstract

Periodontal disease is one of the most common causes of tooth loss among adults. Research shows that inflammation is one of the crucial components in the initiation and progression of periodontitis. Various herbal medicines have recently been receiving attention for the management of periodontitis owing to their general safety and efficacy. Curcumin, a bioactive polyphenol extracted from Curcuma longa, has been shown to possess antioxidant, antimicrobial, anti-inflammatory and analgesic properties. Several studies have assessed the efficacy of curcumin against periodontal diseases. These studies have shown equivalent or even higher efficacy of curcumin compared to the commonly used medications for the management of periodontitis such as chlorhexidine. Herein, we review the experimental and clinical findings on the anti-periodontitis effects of curcumin and the pharmacological mechanisms underlying these effects.

Keywords: Inflammation, gingivitis, herbal medicine, curcumin, periodontitis, herbal mouthwash.

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