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Mini-Review Article

在卵巢上皮癌患者的随访中，HE4是否优于CA-125？

卷 21, 期 10, 2020

页: [1026 - 1033] 页: 8

弟呕挨: 10.2174/1389450121666200425211732

价格: $65

摘要

尽管在上皮性卵巢癌（EOC）的治疗方面取得了重要进展，但该疾病仍然是妇科恶性肿瘤导致全球高死亡率的主要原因。 EOC的复发是不可避免的，这是导致存活率低的原因。 与后续的标准碳水化合物抗原-125（CA-125）相比，迫切需要具有更高准确性的新型有效生物标记。 人附睾蛋白4（HE4）用于EOC的早期检测（ROMA算法）以及预测新辅助化疗后的最佳细胞减少和生存结果。 值得注意的是，新兴的HE4是一种有前途的预后生物标志物，在各种最新的检测复发性疾病的研究中显示出更高的准确性。 在这份小型回顾中，我们讨论了HE4作为EOC复发的准确预测指标的潜力。

关键词: HE4，预后生物标志物，卵巢癌，复发，随访，生存率。

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