Login Register Cart 0
Generic placeholder image

Infectious Disorders - Drug Targets

Editor-in-Chief

ISSN (Print): 1871-5265
ISSN (Online): 2212-3989

Back
Journal Home About Journal Editorial Board Journal Insight Current Issue Volumes/Issues
Subscribe
Case Report

Brucella Pneumonia with Systemic Complications and Pancytopenia: A Case Report

Author(s): Simin Seyedpour, Behzad Khodaei, Malihe Hassan Nezhad, SeyedAhmad SeyedAlinaghi and Fereshteh Ghiasvand*

Volume 21, Issue 2, 2021

Published on: 22 April, 2020

Page: [294 - 296] Pages: 3

DOI: 10.2174/1871526520666200422110306

Price: $65

Abstract

Background: Iran, which is regarded as an endemic region for brucellosis, ranks second in brucella prevalence in the world. Pulmonary involvement is a rare complication of brucellosis. In this article, we aimed to report a case of systemic brucellosis complicated with brucella pneumonia.

Case Presentation: A 39-years-old man was referred to the emergency department with weakness, productive coughs and severe weight loss during 8 months. Agglutination tests for brucellosis showed high titers suggestive for brucella infection. After 6 days of treatment, the patients’ clinical state improved significantly.

Conclusion: The patient had systemic signs and bone marrow suppression with pulmonary involvement that his diagnosis confirmed with delay after one year, but with treatment, he had a very good outcome.

Keywords: Brucellosis, pneumonia, pancytopenia, complication, case report, systemic.

Graphical Abstract

[1]
Harrison, E.R.; Posada, R. Brucellosis. Pediatr. Rev., 2018, 39(4), 222-224.
[http://dx.doi.org/10.1542/pir.2017-0126] [PMID: 29610436]
[2]
Mirnejad, R.; Jazi, F.M.; Mostafaei, S.; Sedighi, M. Epidemiology of brucellosis in Iran: A comprehensive systematic review and meta-analysis study. Microb. Pathog., 2017, 109, 239-247.
[http://dx.doi.org/10.1016/j.micpath.2017.06.005] [PMID: 28602839]
[3]
Pappas, G.; Akritidis, N.; Bosilkovski, M.; Tsianos, E. Brucellosis. N. Engl. J. Med., 2005, 352(22), 2325-2336.
[http://dx.doi.org/10.1056/NEJMra050570] [PMID: 15930423]
[4]
Buzgan, T.; Karahocagil, M.K.; Irmak, H.; Baran, A.I.; Karsen, H.; Evirgen, O.; Akdeniz, H. Clinical manifestations and complications in 1028 cases of brucellosis: a retrospective evaluation and review of the literature. Int. J. Infect. Dis., 2010, 14(6), e469-e478.
[http://dx.doi.org/10.1016/j.ijid.2009.06.031] [PMID: 19910232]
[5]
Dean, A.S.; Crump, L.; Greter, H.; Hattendorf, J.; Schelling, E.; Zinsstag, J. Clinical manifestations of human brucellosis: a systematic review and meta-analysis. PLoS Negl. Trop. Dis., 2012, 6(12), e1929.
[http://dx.doi.org/10.1371/journal.pntd.0001929] [PMID: 23236528]
[6]
Zheng, R. A systematic review and meta-analysis of epidemiology and clinical manifestations of human brucellosis in China. BioMed research international, 2018, 2018, 5712920.
[http://dx.doi.org/10.1155/2018/5712920]
[7]
Solera, J.; Solís García Del Pozo, J. Treatment of pulmonary brucellosis: a systematic review. Expert Rev. Anti Infect. Ther., 2017, 15(1), 33-42.
[http://dx.doi.org/10.1080/14787210.2017.1254042] [PMID: 27790937]
[8]
Erdem, H.; Inan, A.; Elaldi, N.; Tekin, R.; Gulsun, S.; Ataman-Hatipoglu, C.; Beeching, N.; Deveci, Ö.; Yalci, A.; Bolukcu, S.; Dagli, O. Brucellosis Study Group. Respiratory system involvement in brucellosis: the results of the Kardelen study. Chest, 2014, 145(1), 87-94.
[http://dx.doi.org/10.1378/chest.13-0240] [PMID: 23907372]
[9]
Lubani, M.M.; Lulu, A.R.; Araj, G.F.; Khateeb, M.I.; Qurtom, M.A.; Dudin, K.I. Pulmonary brucellosis. Q. J. Med., 1989, 71(264), 319-324.
[PMID: 2594962]
[10]
Mousa, A.M.; Muhtaseb, S.A.; Al-Mudallal, D.S.; Marafie, A.A.; Habib, F.M. Brucellar sternoclavicular arthritis, the forgotten complication. Ann. Trop. Med. Parasitol., 1988, 82(3), 275-281.
[http://dx.doi.org/10.1080/00034983.1988.11812244] [PMID: 3250341]
[11]
Dilek, I. Hematological complications in 787 cases of acute brucellosis in eastern Turkey. Turk. J. Med. Sci., 2008, 38(5), 421-424.

Rights & Permissions Print Cite
Article Metrics
15
© 2024 Bentham Science Publishers | Privacy Policy