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Review Article

半纤维素水凝胶的生物医学应用

卷 27, 期 28, 2020

页: [4647 - 4659] 页: 13

弟呕挨: 10.2174/0929867327666200408115817

价格: $65

摘要

背景:水凝胶具有三维网状结构，能够吸收大量的水/液，并保持其原有结构。半纤维素是植物中仅次于纤维素的第二丰富的多糖，是一种多相多糖，由多种糖类组成。半纤维素独特的物理和化学性质使其成为一种很有前途的水凝胶材料。 方法:首先综述了半纤维素水凝胶的智能性、生物降解性和生物相容性三个研究热点。综述了半纤维素水凝胶的制备及其在药物传递系统和组织工程(关节软骨、细胞固定化和伤口敷料)中的应用进展。 结果:半纤维素水凝胶具有许多独特的性能，如抗氧化性、生物降解性和生物相容性。互穿网络可以赋予水凝胶适当的力学性能。这些特性使半纤维素水凝胶在生物医学应用中很有前途，如药物传递系统和组织工程(关节软骨、细胞固定化和伤口敷料)。 结论:水凝胶在生物医学和组织工程领域有着广泛的应用，如组织填充剂、药物释放剂、酶包封剂、蛋白质电泳、隐形眼镜、人工血浆、人工皮肤、组织工程支架材料等。本文综述了近年来半纤维素水凝胶的制备及其在生物医学领域的应用进展。

关键词: 智能水凝胶，生物相容性，生物降解性，药物传递系统，组织工程，半纤维素水凝胶。

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