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当代阿耳茨海默病研究

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ISSN (Print): 1567-2050
ISSN (Online): 1875-5828

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Review Article

基于虚拟现实的轻度认知障碍的检测：范围回顾

卷 17, 期 2, 2020

页: [126 - 140] 页: 15

弟呕挨: 10.2174/1567205017666200317100421

价格: $65

摘要

背景：为了延缓认知能力下降并减少痴呆症的发生，有必要对轻度认知障碍（MCI）进行精确检测。虚拟现实（VR）技术在这种检测中的应用可以克服传统纸笔测试的不足。 目的：本综述旨在总结利用VR技术检测MCI的研究进展。 方法：系统地搜索了从成立到2019年11月19日的八个数据库，以研究将VR应用于MCI检测的研究。根据特定的检测目的进行了主题分析，并总结了评估的主要对应认知域；还概述了VR应用程序的特征。 结果：最终包括28个研究。检测目的包括区分健康对照者和MCI患者，aMCI亚型，检测患有阿尔茨海默氏病（AD）风险的MCI患者，以及区分MCI和AD。评估空间记忆的VR任务适用于所有检测目的，记忆和执行功能组合的评估似乎更为敏感。可以评估执行功能和意向性情景记忆，以区分健康对照，MCI患者和AD患者。偶发性情景记忆可有效检测MCI伴海马萎缩。 VR应用程序的最常见特征是使用半浸入式，操纵杆或游戏手柄交互以及简单的一次性行为评估。 结论：VR应用在MCI的检测中很有前途，但需要进一步研究以用于临床。

关键词: 轻度认知障碍，痴呆，检测，辨别，虚拟现实，范围界定审查。

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