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Endocrine, Metabolic & Immune Disorders - Drug Targets

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ISSN (Print): 1871-5303
ISSN (Online): 2212-3873

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Review Article

Nickel and Skin: From Allergy to Autoimmunity

Author(s): Kossara Drenovska*, Martin Shahid and Snejina Vassileva

Volume 20, Issue 7, 2020

Page: [1032 - 1040] Pages: 9

DOI: 10.2174/1871530320666191231115437

Price: $65

Abstract

Introduction & Objectives: Cutaneous and systemic reactions to various metal implants and medical devices have been well documented. The aim of this review was to focus on the probable common mechanisms of allergy and autoimmunity that may lead to similar clinical outcomes following the growing evidence in the literature of metal and nickel-related systemic, autoimmune or autoinflammatory disorders.

Methods: Detailed search of the available electronic databases (PubMed-Medline) was conducted for review of the literature on that topic till the present moment.

Results: Multiple reports on the immunological effects of metals including immunomodulation, allergy, or autoimmunity were identified. It was found that metals may act through immunosuppression, immunotoxicity, or as immune adjuvants thus provoking allergy and autoimmunity in susceptible individuals. Both external or internal exposure to metals was observed. Nickel has been identified as the most common sensitizer, and also the most studied one. The coexistence of both allergic and autoimmune symptoms, induced by nickel, has been published, suggesting the autoimmune potential of nickel compounds.

Conclusion: Clinical experience and scientific literature together demonstrate that metals may play an important role in the development of autoimmune diseases. While metal implant allergies and complications are on the rise, they remain a diagnostic and therapeutic challenge. Elucidation of their possible mechanisms will contribute to the more successful and safer treatment of affected individuals.

Keywords: Autoimmune blistering diseases, autoimmune skin disorders, connective tissue diseases, contact dermatitis, medical devices, metals and autoimmunity, metal implants, nickel allergy, nickel hypersensitivity.

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Graphical Abstract

[1]
Stejskal, V. Allergy and autoimmunity caused by metals: A unifying concept. In: Vaccines and Autoimmunity; Yehuda, Shoenfeld.; Nancy, Agmon‐Levin.; Lucija, Tomljenovic., Eds.; Wiley Online Library, 2015; pp. 57-64.
[http://dx.doi.org/10.1002/9781118663721.ch5]
[2]
Schiraldi, M.; Monestier, M. How can a chemical element elicit complex immunopathology? Lessons from mercury-induced autoimmunity. Trends Immunol., 2009, 30(10), 502-509.
[http://dx.doi.org/10.1016/j.it.2009.07.005] [PMID: 19709928]
[3]
Ingalls, T.H. Endemic clustering of multiple sclerosis in time and place, 1934-1984. Confirmation of a hypothesis. Am. J. Forensic Med. Pathol., 1986, 7(1), 3-8.
[http://dx.doi.org/10.1097/00000433-198603000-00002] [PMID: 3728417]
[4]
Niedziela, M.; Bluvshteyn-Walker, S. Autoimmune thyroid disease and allergic contact dermatitis: Two immune-related pathologies in the same patient. J. Pediatr. Endocrinol. Metab., 2012, 25(1-2), 31-32.
[http://dx.doi.org/10.1515/jpem-2011-0392] [PMID: 22570947]
[5]
Kounis, N.G.; Koniari, I. Hypersensitivity to metallic implants: Pathophysiologic and diagnostic considerations. Acta Biomed., 2018, 89(3), 428-429.
[PMID: 30333472]
[6]
Kettelarij, J.A.B.; Lidén, C.; Axén, E.; Julander, A. Cobalt, nickel and chromium release from dental tools and alloys. Contact Dermat., 2014, 70(1), 3-10.
[http://dx.doi.org/10.1111/cod.12111] [PMID: 23844864]
[7]
Symeonides, P.P.; Paschaloglou, C.; Papageorgiou, S. An allergic reaction after internal fixation of a fracture using a vitallium plate. J. Allergy Clin. Immunol., 1973, 51(4), 251-252.
[http://dx.doi.org/10.1016/0091-6749(73)90145-0] [PMID: 4689142]
[8]
McKenzie, A.W.; Aitken, C.V.; Ridsdill-Smith, R. Urticaria after insertion of Smith-Petersen Vitallium nail. BMJ, 1967, 4(5570), 36.
[http://dx.doi.org/10.1136/bmj.4.5570.36] [PMID: 6047831]
[9]
Thomas, P.; Thomas, M.; Summer, B.; Dietrich, K.; Zauzig, M.; Steinhauser, E.; Krenn, V.; Arnholdt, H.; Flaig, M.J. Impaired wound-healing, local eczema, and chronic inflammation following titanium osteosynthesis in a nickel and cobalt-allergic patient: A case report and review of the literature. J. Bone Joint Surg. Am., 2011, 93(11) e61
[http://dx.doi.org/10.2106/JBJS.J.00317] [PMID: 21655880]
[10]
Kubba, R.; Taylor, J.S.; Marks, K.E. Cutaneous complications of orthopedic implants. A two-year prospective study. Arch. Dermatol., 1981, 117(9), 554-560.
[http://dx.doi.org/10.1001/archderm.1981.01650090036021] [PMID: 7294846]
[11]
Delimar, D.; Bohaček, I.; Paštar, Z.; Lipozenčić, J. Orthopedic and cutaneous reactions to nickel after total hip replacement. Acta Dermatovenerol. Croat., 2018, 26(1), 39-43.
[PMID: 29782298]
[12]
Lyell, A.; Bain, W.H. Letter: Nickel allergy and valve replacement. Lancet, 1974, 1(7854), 408-409.
[http://dx.doi.org/10.1016/S0140-6736(74)93174-2] [PMID: 4131055]
[13]
Lyell, A.; Bain, W.H.; Thomson, R.M. Repeated failure of nickel-containing prosthetic heart valves in a patient allergic to nickel. Lancet, 1978, 2(8091), 657-659.
[http://dx.doi.org/10.1016/S0140-6736(78)92763-0] [PMID: 80580]
[14]
Almpanis, G.C.; Tsigkas, G.G.; Koutsojannis, C.; Mazarakis, A.; Kounis, G.N.; Kounis, N.G. Nickel allergy, Kounis syndrome and intracardiac metal devices. Int. J. Cardiol., 2010, 145(2), 364-365.
[http://dx.doi.org/10.1016/j.ijcard.2010.02.038] [PMID: 20207036]
[15]
Pacheco, K.A. Allergy to surgical implants. Clin. Rev. Allergy Immunol., 2019, 56(1), 72-85.
[http://dx.doi.org/10.1007/s12016-018-8707-y] [PMID: 30220068]
[16]
Thyssen, J.P. Nickel and cobalt allergy before and after nickel regulation--evaluation of a public health intervention. Contact Dermat., 2011, 65(Suppl. 1), 1-68.
[http://dx.doi.org/10.1111/j.1600-0536.2011.01957.x] [PMID: 21777241]
[17]
Thyssen, J.P.; Menné, T. Metal allergy--A review on exposures, penetration, genetics, prevalence, and clinical implications. Chem. Res. Toxicol., 2010, 23(2), 309-318.
[http://dx.doi.org/10.1021/tx9002726] [PMID: 19831422]
[18]
Lian, B.S.Y.; McFadden, J.P.; Lee, S.X. Nickel by proxy. Contact Dermat., 2019, 81(1), 69.
[http://dx.doi.org/10.1111/cod.13232] [PMID: 30677153]
[19]
Cruz, M.J.; Costa, R.; Marquilles, E.; Morell, F.; Muñoz, X. Occupational asthma caused by chromium and nickel. Arch. Bronconeumol., 2006, 42(6), 302-306.
[http://dx.doi.org/10.1016/S1579-2129(06)60147-X] [PMID: 16827980]
[20]
van Kampen, V.; Merget, R.; Brüning, T. Immediate type allergies due to metal - nickel. Pneumologie, 2003, 57(11), 667-670.
[PMID: 14618511]
[21]
Lieberman, P.; Fonacier, L. Systemic contact dermatitis possibly related to metal implants. J. Allergy Clin. Immunol. Pract., 2014, 2(4), 487.
[http://dx.doi.org/10.1016/j.jaip.2014.02.008] [PMID: 25017546]
[22]
Andrioli, M.; Trimboli, P.; Maio, D.; Persani, L.; Minelli, M. Systemic nickel allergic syndrome as an immune-mediated disease with an increased risk for thyroid autoimmunity. Endocrine, 2015, 50(3), 807-810.
[http://dx.doi.org/10.1007/s12020-015-0581-2] [PMID: 25795291]
[23]
Mosca, M.; Tani, C.; Neri, C.; Baldini, C.; Bombardieri, S. Undifferentiated connective tissue diseases (UCTD). Autoimmun. Rev., 2006, 6(1), 1-4.
[http://dx.doi.org/10.1016/j.autrev.2006.03.004] [PMID: 17110308]
[24]
Andreoli, L.; Tincani, A. Undifferentiated connective tissue disease, fibromyalgia and the environmental factors. Curr. Opin. Rheumatol., 2017, 29(4), 355-360.
[http://dx.doi.org/10.1097/BOR.0000000000000392] [PMID: 28368979]
[25]
Shoenfeld, Y.; Agmon-Levin, N. ‘ASIA’ - autoimmune/inflammatory syndrome induced by adjuvants. J. Autoimmun., 2011, 36(1), 4-8.
[http://dx.doi.org/10.1016/j.jaut.2010.07.003] [PMID: 20708902]
[26]
Cojocaru, M.; Chicoş, B. ASIA or Shoenfeld’s syndrome--an autoimmune syndrome induced by adjuvants. Rom. J. Intern. Med., 2013, 51(3-4), 131-134.
[PMID: 24620624]
[27]
Loyo, E.; Jara, L.J.; López, P.D.; Puig, A.C. Autoimmunity in connection with a metal implant: A case of autoimmune/autoinflammatory syndrome induced by adjuvants. Auto Immun. Highlights, 2012, 4(1), 33-38.
[http://dx.doi.org/10.1007/s13317-012-0044-1] [PMID: 26000140]
[28]
Watad, A.; Quaresma, M.; Brown, S.; Cohen Tervaert, J.W.; Rodríguez-Pint, I.; Cervera, R.; Perricone, C.; Shoenfeld, Y. Autoimmune/inflammatory syndrome induced by adjuvants (Shoenfeld’s syndrome) - An update. Lupus, 2017, 26(7), 675-681.
[http://dx.doi.org/10.1177/0961203316686406] [PMID: 28059022]
[29]
Cohen Tervaert, J.W. Autoinflammatory/autoimmunity syndrome induced by adjuvants (ASIA; Shoenfeld’s syndrome): A new flame. Autoimmun. Rev., 2018, 17(12), 1259-1264.
[http://dx.doi.org/10.1016/j.autrev.2018.07.003] [PMID: 30316995]
[30]
Barnett, J.H. Discoid lupus erythematosus exacerbated by contact dermatitis. Cutis, 1990, 46(5), 430-432.
[PMID: 2261802]
[31]
Lukacs, A.; Karpati, S.; Temesvari, E. Nickel-induced Koebner phenomenon in chronic cutaneous lupus erythematosus. J. Dtsch. Dermatol. Ges., 2011, 9(6), 475-476.
[http://dx.doi.org/10.1111/j.1610-0387.2010.07589.x] [PMID: 21199366]
[32]
Kosboth, M.; Chin-Loy, A.; Lyons, R.; Wesson, S.K.; Reeves, W.H. Malar rash caused by metal allergy in a patient with systemic lupus erythematosus. Nat. Clin. Pract. Rheumatol., 2007, 3(4), 240-245.
[http://dx.doi.org/10.1038/ncprheum0464] [PMID: 17396110]
[33]
Bjørklund, G.; Dadar, M.; Aaseth, J. Delayed-type hypersensitivity to metals in connective tissue diseases and fibromyalgia. Environ. Res., 2018, 161, 573-579.
[http://dx.doi.org/10.1016/j.envres.2017.12.004] [PMID: 29245125]
[34]
Sakellariou, V.I.; Atsali, E.; Starantzis, K.; Batistaki, C.; Brozou, T.; Pantos, P.; Stathopoulos, K.; Soultanis, K. Postoperative spinal infection mimicking systemic vasculitis with titanium-spinal implants. Scoliosis, 2011, 6(1), 20.
[http://dx.doi.org/10.1186/1748-7161-6-20] [PMID: 21914179]
[35]
Hartmann, D.; Letulé, V.; Schneider, J.J.; Flaig, M.J. Metal implant sensitivity: clinical and histological presentation Hautarzt, 2016, 67(5), 373-379.
[http://dx.doi.org/10.1007/s00105-016-3790-6] [PMID: 27090521]
[36]
Gilaberte, M.; Delclós, J.; Yébenes, M.; Barranco, C.; Pujol, R.M. Delayed foreign body granuloma secondary to an abandoned cardiac pacemaker wire. J. Eur. Acad. Dermatol. Venereol., 2007, 21(1), 107-109.
[http://dx.doi.org/10.1111/j.1468-3083.2006.01797.x] [PMID: 17207180]
[37]
Kootiratrakarn, T.; Kimura, Y.; Matsunaga, J.; Tagami, H. Delayed development of foreign body granuloma from an implanted permanent cardiac pacemaker. J. Dermatol., 2004, 31(6), 460-463.
[http://dx.doi.org/10.1111/j.1346-8138.2004.tb00532.x] [PMID: 15235184]
[38]
Joly, P. Incidence of bullous pemphigoid and pemphigus vulgaris. BMJ, 2008, 337, a209.
[http://dx.doi.org/10.1136/bmj.a209] [PMID: 18614512]
[39]
Roussel, A.; Benichou, J.; Randriamanantany, Z.A.; Gilbert, D.; Drenovska, K.; Houivet, E.; Tron, F.; Joly, P. Enzyme-linked immunosorbent assay for the combination of bullous pemphigoid antigens 1 and 2 in the diagnosis of bullous pemphigoid. Arch. Dermatol., 2011, 147(3), 293-298.
[http://dx.doi.org/10.1001/archdermatol.2011.21] [PMID: 21422336]
[40]
Vassileva, S. Drug-induced pemphigoid: bullous and cicatricial. Clin. Dermatol., 1998, 16(3), 379-387.
[http://dx.doi.org/10.1016/S0738-081X(98)00008-X] [PMID: 9642531]
[41]
Vassileva, S.; Mateev, G.; Balabanova, M.; Tsankov, N. Burn-induced bullous pemphigoid. J. Am. Acad. Dermatol., 1994, 30(6), 1027-1028.
[http://dx.doi.org/10.1016/S0190-9622(09)80149-7] [PMID: 8188869]
[42]
Stransky, L.; Vasileva, S.; Mateev, G. Contact bullous pemphigoid? Contact Dermat., 1996, 35(3), 182.
[http://dx.doi.org/10.1111/j.1600-0536.1996.tb02345.x] [PMID: 8930487]
[43]
Drenovska, K.; Kavaklieva, S.; Vassileva, S.; Kapnilov, D.; Tsankov, N. Bullous pemphigoid associated with carcinoma of the larynx. Bull CEEDVA, 2004, 6, 44-47.
[44]
Kubba, R.; Champion, R.H. Nickel sensitivity resembling bullous pemphigoid. Br. J. Dermatol., 1975, 93, 41-43.
[http://dx.doi.org/10.1111/j.1365-2133.1975.tb06790.x]
[45]
Anderson, C.K.; Mowad, C.M.; Goff, M.E.; Pelle, M.T. Bullous pemphigoid arising in surgical wounds. Br. J. Dermatol., 2001, 145(4), 670-672.
[http://dx.doi.org/10.1046/j.1365-2133.2001.04427.x] [PMID: 11703303]
[46]
Sneddon, I.B.; Church, R. Diagnosis and treatment of pemphigoid; report on 22 cases. BMJ, 1955, 2(4952), 1360-1363.
[http://dx.doi.org/10.1136/bmj.2.4952.1360] [PMID: 13269870]
[47]
Salomon, R.J.; Briggaman, R.A.; Wernikoff, S.Y.; Kayne, A.L. Localized bullous pemphigoid. A mimic of acute contact dermatitis. Arch. Dermatol., 1987, 123(3), 389-392.
[http://dx.doi.org/10.1001/archderm.1987.01660270127031] [PMID: 3545091]
[48]
Venning, V.A.; Wojnarowska, F. Induced bullous pemphigoid. Br. J. Dermatol., 1995, 132(5), 831-832.
[http://dx.doi.org/10.1111/j.1365-2133.1995.tb00739.x] [PMID: 7772498]
[49]
Lo Schiavo, A.; Caccavale, S.; Alfano, R.; Gambardella, A.; Cozzi, R. Bullous pemphigoid initially localized around the surgical wound of an arthroprothesis for coxarthrosis. Int. J. Dermatol., 2014, 53(4), e289-e290.
[http://dx.doi.org/10.1111/ijd.12222] [PMID: 24261580]
[50]
Pardo, J.; Rodrguez-Serna, M.; Mercader, P.; Fortea, J.M. Localized bullous pemphigoid overlying a fistula for hemodialysis. J. Am. Acad. Dermatol., 2004, 51(2)(Suppl.), S131-S132.
[http://dx.doi.org/10.1016/j.jaad.2004.03.024] [PMID: 15280832]
[51]
Torchia, D.; Caproni, M.; Ketabchi, S.; Antiga, E.; Fabbri, P. Bullous pemphigoid initially localized around a urostomy. Int. J. Dermatol., 2006, 45(11), 1387-1389.
[http://dx.doi.org/10.1111/j.1365-4632.2006.03118.x] [PMID: 17076741]
[52]
Lo Schiavo, A.; Ruocco, E.; Brancaccio, G.; Caccavale, S.; Ruocco, V.; Wolf, R. Bullous pemphigoid: Etiology, pathogenesis, and inducing factors: facts and controversies. Clin. Dermatol., 2013, 31(4), 391-399.
[http://dx.doi.org/10.1016/j.clindermatol.2013.01.006] [PMID: 23806156]
[53]
Ruocco, V.; Brunetti, G.; Puca, R.V.; Ruocco, E. The immunocompromised district: A unifying concept for lymphoedematous, herpes-infected and otherwise damaged sites. J. Eur. Acad. Dermatol. Venereol., 2009, 23(12), 1364-1373.
[http://dx.doi.org/10.1111/j.1468-3083.2009.03345.x] [PMID: 19548975]
[54]
Zeng, R.; Chen, H.; Jiang, Y.; Li, M. Bullous pemphigoid after femur fracture surgery: A mere coincidence? Indian J. Dermatol. Venereol. Leprol., 2014, 80(2), 195.
[http://dx.doi.org/10.4103/0378-6323.129438] [PMID: 24685881]
[55]
Singh, D.; Swann, A. Bullous pemphigoid after bilateral forefoot surgery. Foot Ankle Spec., 2015, 8(1), 68-72.
[http://dx.doi.org/10.1177/1938640014546865] [PMID: 25142916]
[56]
Kosi, L.; Perić, J.; Pantović, M.; Bijelić, G.; Vukićević Sretenović, J.; Škiljević, D. Localized bullous pemphigoid on the site of knee arthroplasty: a case report. Serbian J. Dermatol. Venereol., 2016, 8, 39-44.
[http://dx.doi.org/10.1515/sjdv-2016-0004]
[57]
Shahid, M.; Drenovska, K.; Kazandjieva, J.; Balabanova, M.; Miteva, L.; Vassileva, S. Implant-related allergic contact dermatitis and bullous pemphigoid. 14th EADV Spring Symp., 2017.
[58]
Darlenski, R.; Vassileva, S.; Drenovska, K.; Marina, S.; Serafimova, D.; Balabanova, M.; Bardarov, E.; Broshtilova, V.; Kazandjieva, J.; Botev, I.; Stransky, L. Bullous pemphigoid following pacemaker implantation. XVI Sci. Conf. Sofia Dermatol. Days, 2006.
[59]
Tomov, T.; Drenovska, K.; Chavdarovski, P.; Shahid, M.; Balabanova, M.; Miteva, L.; Vassileva, S. Bullous pemphigoid after pacemaker implantation. XVI Sci. Conf. Sofia Dermatol. Days, 2017.
[60]
Atakan, N.; Tüzün, J.; Karaduman, A. Dyshidrosiform pemphigoid induced by nickel in the diet. Contact Dermat., 1993, 29(3), 159-160.
[http://dx.doi.org/10.1111/j.1600-0536.1993.tb03520.x] [PMID: 8222634]
[61]
Dănescu, S.; Chiorean, R.; Macovei, V.; Sitaru, C.; Baican, A. Role of physical factors in the pathogenesis of bullous pemphigoid: Case report series and a comprehensive review of the published work. J. Dermatol., 2016, 43(2), 134-140.
[http://dx.doi.org/10.1111/1346-8138.13031] [PMID: 26173987]
[62]
Black, M.; Mignogna, M.D.; Scully, C.; Number, I.I.; Number, I.I. Pemphigus vulgaris. Oral Dis., 2005, 11(3), 119-130.
[http://dx.doi.org/10.1111/j.1601-0825.2005.01139.x] [PMID: 15888101]
[63]
Lin, M.S.; Mascaró, J.M., Jr; Liu, Z.; España, A.; Diaz, L.A. The desmosome and hemidesmosome in cutaneous autoimmunity. Clin. Exp. Immunol., 1997, 107(Suppl. 1), 9-15.
[PMID: 9020929]
[64]
Anhalt, G.J.; Kim, S.C.; Stanley, J.R.; Korman, N.J.; Jabs, D.A.; Kory, M.; Izumi, H.; Ratrie, H., III; Mutasim, D.; Ariss-Abdo, L. Paraneoplastic pemphigus. An autoimmune mucocutaneous disease associated with neoplasia. N. Engl. J. Med., 1990, 323(25), 1729-1735.
[http://dx.doi.org/10.1056/NEJM199012203232503] [PMID: 2247105]
[65]
Laskaris, G.; Satriano, R.A. Drug-induced blistering oral lesions. Clin. Dermatol., 1993, 11(4), 545-550.
[http://dx.doi.org/10.1016/0738-081X(93)90164-8] [PMID: 8124645]
[66]
Brenner, S.; Tur, E.; Shapiro, J.; Ruocco, V.; D’Avino, M.; Ruocco, E.; Tsankov, N.; Vassileva, S.; Drenovska, K.; Brezoev, P.; Barnadas, M.A.; Gonzalez, M.J.; Anhalt, G.; Nousari, H.; Ramos-e-Silva, M.; Pinto, K.T.; Miranda, M.F.; Silva, M.R. Pemphigus vulgaris: environmental factors. Occupational, behavioral, medical, and qualitative food frequency questionnaire. Int. J. Dermatol., 2001, 40(9), 562-569.
[http://dx.doi.org/10.1046/j.1365-4362.2001.01266.x] [PMID: 11737449]
[67]
Lynfield, Y.L.; Pertschuk, L.P.; Zimmerman, A. Pemphigus erythematosus provoked by allergic contact dermatitis. Occurrence many years after thymoma removal. Arch. Dermatol., 1973, 108(5), 690-693.
[http://dx.doi.org/10.1001/archderm.1973.01620260038014] [PMID: 4584307]
[68]
Dimitrowa, J.; Obreschkowa, E.; Tsankov, N.; Zaimova, Z. Pemphigus vulgaris induziert durch ultraviolette Strahlen und das pestizid Baytan. Dtcsh Dermatol., 1984, 32, 971-976.
[69]
Tsankov, N.; Dimitrowa, J.; Obreschkowa, E.; Lasarowa, A. Induced pemphigus caused by the pesticide phosphamide Z. Hautkr., 1987, 62(3), 196-201.
[PMID: 2953118]
[70]
Tsankov, N.; Stransky, L.; Kostowa, M.; Mitrowa, Z.; Obreschkowa, E. Induzierter pemphigus durch berufliche Kontakt mit Basochrom. Dermatosen, 1990, 38, 91-93.
[PMID: 2142918]
[71]
Brenner, S.; Wolf, R.; Ruocco, V. Contact pemphigus: a subgroup of induced pemphigus. Int. J. Dermatol., 1994, 33(12), 843-845.
[http://dx.doi.org/10.1111/j.1365-4362.1994.tb01016.x] [PMID: 7883405]
[72]
Stransky, L. Contact pemphigus vulgaris? Contact Dermat., 1998, 38(1), 45.
[http://dx.doi.org/10.1111/j.1600-0536.1998.tb05639.x] [PMID: 9504249]
[73]
Thongprasom, K.; Suvanpiyasiri, C.; Wongsa, A.S.; Iamaroon, A.; Korkij, W.; Lohwongwatana, B.; Sinpitaksakul, S.; Nakpipat, P. Oralne lezije nalik pemphigusu vulgarisu prouzročene niklom. Acta Stomatol. Croat., 2011, 45, 202-208.
[74]
Guéniche, A.; Viac, J.; Lizard, G.; Charveron, M.; Schmitt, D. Effect of various metals on intercellular adhesion molecule-1 expression and tumour necrosis factor alpha production by normal human keratinocytes. Arch. Dermatol. Res., 1994, 286(8), 466-470.
[http://dx.doi.org/10.1007/BF00371573] [PMID: 7864660]
[75]
Hostýnek, J.J. Nickel-induced hypersensitivity: etiology, immune reactions, prevention and therapy. Arch. Dermatol. Res., 2002, 294(6), 249-267.
[http://dx.doi.org/10.1007/s00403-002-0319-x] [PMID: 12192489]
[76]
Ruocco, V.; De Angelis, E.; Lombardi, M.L. Drug-induced pemphigus. II. Pathomechanisms and experimental investigations. Clin. Dermatol., 1993, 11(4), 507-513.
[http://dx.doi.org/10.1016/0738-081X(93)90158-9] [PMID: 8124640]
[77]
Altin, N.; Ergun, S.; Katz, J.; Sancakli, E.; Koray, M.; Tanyeri, H. Implant-supported oral rehabilitation of a patient with pemphigus vulgaris: a clinical report. J. Prosthodont., 2013, 22(7), 581-586.
[http://dx.doi.org/10.1111/jopr.12050] [PMID: 23552022]
[78]
Allen, J.; Wojnarowska, F. Linear IgA disease: The IgA and IgG response to dermal antigens demonstrates a chiefly IgA response to LAD285 and a dermal 180-kDa protein. Br. J. Dermatol., 2003, 149(5), 1055-1058.
[http://dx.doi.org/10.1111/j.1365-2133.2003.05647.x] [PMID: 14632815]
[79]
Kelly, S.E.; Frith, P.A.; Millard, P.R.; Wojnarowska, F.; Black, M.M. A clinicopathological study of mucosal involvement in linear IgA disease. Br. J. Dermatol., 1988, 119(2), 161-170.
[http://dx.doi.org/10.1111/j.1365-2133.1988.tb03197.x] [PMID: 3048368]
[80]
Girão, L.; Fiadeiro, T.; Rodrigues, J.C. Burn-induced linear IgA dermatosis. J. Eur. Acad. Dermatol. Venereol., 2000, 14(6), 507-510.
[http://dx.doi.org/10.1046/j.1468-3083.2000.00158.x] [PMID: 11444277]
[81]
Gilligan, G.M.; Galíndez-Costa, M.F.; Moine, L.; Sambuelli, G.; Panico, R.L. Bullous disease after dental implant placement procedure: a case report highlighting clinical aspects. J. Oral Diagn., 2018, 3, 1-8.
[82]
Wollina, U.; Fünfstück, V.; Hipler, C.; Knopf, B. Alterations of epidermal lectin binding sites in acute contact dermatitis. Contact Dermat., 1988, 19(2), 109-115.
[http://dx.doi.org/10.1111/j.1600-0536.1988.tb05506.x] [PMID: 3053029]
[83]
Al-Mogairen, S.M.; Al-Arfaj, A.S.; Meo, S.A.; Adam, M.; Al-Hammad, A.; Gad El Rab, M.O. Induction of autoimmunity in Brown Norway rats by oral and parenteral administration of sodium silicate. Lupus, 2009, 18(5), 413-417.
[http://dx.doi.org/10.1177/0961203308098192] [PMID: 19318393]
[84]
Büdinger, L.; Hertl, M. Immunologic mechanisms in hypersensitivity reactions to metal ions: an overview. Allergy, 2000, 55(2), 108-115.
[http://dx.doi.org/10.1034/j.1398-9995.2000.00107.x] [PMID: 10726725]
[85]
Schmidt, M.; Raghavan, B.; Müller, V.; Vogl, T.; Fejer, G.; Tchaptchet, S.; Keck, S.; Kalis, C.; Nielsen, P.J.; Galanos, C.; Roth, J.; Skerra, A.; Martin, S.F.; Freudenberg, M.A.; Goebeler, M. Crucial role for human Toll-like receptor 4 in the development of contact allergy to nickel. Nat. Immunol., 2010, 11(9), 814-819.
[http://dx.doi.org/10.1038/ni.1919] [PMID: 20711192]
[86]
Rachmawati, D.; Muris, J.; Scheper, R.J.; Rustemeyer, T.; Kleverlaan, C.J.; Feilzer, A.J.; von Blomberg, B.M.E.; van Hoogstraten, I.M.W. Continuing the quest for autoimmunity due to oral metal exposure. Autoimmunity, 2015, 48(7), 494-501.
[http://dx.doi.org/10.3109/08916934.2015.1033688] [PMID: 25915572]
[87]
Wang, Y.; Dai, S. Structural basis of metal hypersensitivity. Immunol. Res., 2013, 55(1-3), 83-90.
[http://dx.doi.org/10.1007/s12026-012-8351-1] [PMID: 22983897]
[88]
Just, A.; Kall, J. Autoimmune diseases and metal implants and devices; , 2018, pp. 1-20.
[89]
Stejskal, V.; Hudecek, R.; Stejskal, J.; Sterzl, I. Diagnosis and treatment of metal-induced side-effects. Neuroendocrinol. Lett., 2006, 27(Suppl. 1), 7-16.
[PMID: 17261999]
[90]
Teo Wendy, Z.W.; Schalock, P.C. Hypersensitivity reactions to implanted metal devices: facts and fictions. J. Investig. Allergol. Clin. Immunol., 2016, 26(5), 279-294.
[http://dx.doi.org/10.18176/jiaci.0095] [PMID: 27763855]
[91]
Basko-Plluska, J.L.; Thyssen, J.P.; Schalock, P.C. Cutaneous and systemic hypersensitivity reactions to metallic implants. Dermatitis, 2011, 22(2), 65-79.
[http://dx.doi.org/10.2310/6620.2011.10055] [PMID: 21504692]

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