Electrodeposition of Polysaccharide and Protein Hydrogels for Biomedical Applications

doi:10.2174/0929867326666191212163955
摘要

在过去的几十年里，多糖和蛋白质水凝胶得到了广泛的关注，并在各个工程领域得到了广泛的应用。多糖和蛋白质水凝胶具有良好的生物降解性、生物相容性、无毒性和刺激反应性等特性，已被用于满足不同的生物医学应用。采用化学交联、光交联、接枝聚合、疏水相互作用、聚电解质络合和电沉积等方法制备多糖和蛋白质水凝胶。电沉积是制备不同多糖和蛋白质水凝胶的简便方法，具有时空可控性。综述了近年来电沉积不同多糖和蛋白质水凝胶的研究进展。讨论了电化学方法中pH诱导组装、Ca2+交联、金属离子诱导组装、氧化诱导组装的策略。综述了电沉积法制备的具有多种功能的纯、二元和三元混合多糖和蛋白质水凝胶。此外，我们还综述了这些水凝胶在药物传递、组织工程和伤口敷料等方面的应用。
关键词: 电沉积，水凝胶，壳聚糖，蚕丝，生物医学，蛋白质水凝胶，多糖水凝胶。
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DOI https://dx.doi.org/10.2174/0929867326666191212163955	Print ISSN 0929-8673
Publisher Name Bentham Science Publisher	Online ISSN 1875-533X
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