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Letters in Organic Chemistry

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ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

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Research Article

A Novel Copper-Catalyzed Synthesis of N-Monosubstituted 2-Alkynimidamides from 1-Alkynes and Trichloroacetamidines

Author(s): Hossein Fasihi Dastjerdi, Manijeh Nematpour, Elham Rezaee, Mehdi Jahani and Sayyed Abbas Tabatabai*

Volume 17, Issue 9, 2020

Page: [704 - 708] Pages: 5

DOI: 10.2174/1570178616666191023142821

Price: $65

Abstract

A one-pot Cu-catalyzed synthesis of functionalized alkynyl imidamide by terminal alkynes, trichloroacetonitrile and aniline or benzyl amine is reported. The compounds were produced via coupling reaction of terminal alkynes with trichloroacetamidine. This method was performed under mild, ligand-free conditions and easy work-up method.

Keywords: Terminal alkynes, copper iodide, alkynylimidamide, cross-coupling, aniline, one-pot reaction.

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