Search Result "trastuzumab-DM1"


Non-Clinical Disposition and Metabolism of DM1, a Component of Trastuzumab Emtansine (T-DM1), in Sprague Dawley Rats

Journal: Drug Metabolism Letters
Volume: 9 Issue: 2 Year: 2015 Page: 119-131
Author(s): Ben-Quan Shen,Daniela Bumbaca,Qin Yue,Ola Saad,Jay Tibbitts,S. Cyrus Khojasteh,Sandhya Girish

Catabolic Fate and Pharmacokinetic Characterization of Trastuzumab Emtansine (T-DM1): an Emphasis on Preclinical and Clinical Catabolism

Journal: Current Drug Metabolism
Volume: 13 Issue: 7 Year: 2012 Page: 901-910
Author(s): Ben-Quan Shen,Daniela Bumbaca,Ola Saad,Qin Yue,Cinthia V. Pastuskovas,S. Cyrus Khojasteh,Jay Tibbitts,Surinder Kaur,Bei Wang,Yu-Waye Chu,Patricia M. LoRusso,Sandhya Girish

Drug Interaction Potential of Trastuzumab Emtansine (T-DM1) Combined with Pertuzumab in Patients With HER2-Positive Metastatic Breast Cancer

Journal: Current Drug Metabolism
Volume: 13 Issue: 7 Year: 2012 Page: 911-922
Author(s): Dan Lu,Howard A. Burris III,Bei Wang,E. Claire Dees,Javier Cortes,Amita Joshi,Manish Gupta,Joo-Hee Yi,Yu-Waye Chu,Ted Shih,Liang Fang,Sandhya Girish

Review Article

T-DM1 in the Neo-Adjuvant Treatment of HER2-Positive Breast Cancer: Impact of the KRISTINE (TRIO-021) Trial

Journal: Reviews on Recent Clinical Trials
Volume: 12 Issue: 3 Year: 2017 Page: 216-222
Author(s): Alicia FC Okines

Understanding Trastuzumab Resistance in HER2 Positive Breast Cancer and Further Therapeutic Options

Journal: Current Cancer Therapy Reviews
Volume: 11 Issue: 4 Year: 2015 Page: 269-291
Author(s): Sangmee Bae,Sara Hurvitz

Review Article

Toxicology of Trastuzumab: An Insight into Mechanisms of Cardiotoxicity

Journal: Current Cancer Drug Targets
Volume: 19 Issue: 5 Year: 2019 Page: 400-407
Author(s): Jie An,M. Saeed Sheikh

Anti-HER2 Therapy in Elderly Breast Cancer Patients

Journal: Reviews on Recent Clinical Trials
Volume: 9 Issue: 4 Year: 2014 Page: 263-266
Author(s): Masataka Sawaki

HER2 Targeted Monoclonal Antibodies and Tyrosine Kinase Inhibitors

Ebook: Frontiers in Anti-Cancer Drug Discovery
Volume: 4 Year: 2014
Author(s): Neil A. O`Brien,Alexandra Canonici,Karen Howe,Martina S.J. McDermott,Denis M. Collins,Brigid C. Browne,John Crown,Norma O`Donovan
Doi: 10.2174/978160859225114040007

How New Drugs Are Developed: Drug Delivery

Ebook: Medicinal Chemistry - Fusion of Traditional and Western Medicine
Volume: 2 Year: 2014
Author(s): Robert E. Smith
Doi: 10.2174/9781608059744114020009

Review Article open access plus

Neoadjuvant Therapy for HER2-positive Breast Cancer

Journal: Reviews on Recent Clinical Trials
Volume: 12 Issue: 2 Year: 2017 Page: 81-92
Author(s): Rachel Wuerstlein,Nadia Harbeck

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