Search Result "target druggability"


Review Article

Structure-based Druggability Assessment of Anti-virulence Targets from Pseudomonas aeruginosa

Journal: Current Protein & Peptide Science
Volume: 20 Issue: 1 Year: 2019 Page: 1189-1203
Author(s): Thamires Q. Froes,Regina L. Baldini,Sandor Vajda,Marcelo S. Castilho

Druggable Orthosteric and Allosteric Hot Spots to Target Protein-protein Interactions

Journal: Current Pharmaceutical Design
Volume: 20 Issue: 8 Year: 2014 Page: 1293-1301
Author(s): Buyong Ma, Ruth Nussinov

Binding Site Detection and Druggability Prediction of Protein Targets for Structure- Based Drug Design

Journal: Current Pharmaceutical Design
Volume: 19 Issue: 12 Year: 2013 Page: 2326-2333
Author(s): Yaxia Yuan,Jianfeng Pei,Luhua Lai

Druggability of Dynamic Protein-protein Interfaces

Journal: Current Pharmaceutical Design
Volume: 18 Issue: 30 Year: 2012 Page: 4599-4606
Author(s): Ozlem Ulucan,Susanne Eyrisch,Volkhard Helms

Predicting the Druggability of Protein-Protein Interactions Based on Sequence and Structure Features of Active Pockets

Journal: Current Pharmaceutical Design
Volume: 21 Issue: 21 Year: 2015 Page: 3051-3061
Author(s): Xu Dai,RunYu Jing,Yanzhi Guo,YongCheng Dong,YueLong Wang,Yuan Liu,XueMei Pu,Menglong Li

Research Article

Exploring the Lapse in Druggability: Sequence Analysis, Structural Dynamics and Binding Site Characterization of K-RasG12C Variant, a Feasible Oncotherapeutics Target

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 18 Issue: 11 Year: 2018 Page: 1540-1550
Author(s): Emmanuel A. Adeniji,Fisayo A. Olotu,Mahmoud E.S. Soliman

Is Cdc25 a Druggable Target?

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 8 Issue: 8 Year: 2008 Page: 837-842
Author(s): John S. Lazo, Peter Wipf

Untapped Potential of Disordered Proteins in Current Druggable Human Proteome

Journal: Current Drug Targets
Volume: 17 Issue: 10 Year: 2016 Page: 1198-1205
Author(s): Gang Hu,Zhonghua Wu,Kui Wang,Vladimir N. Uversky,Lukasz Kurgan

The Analysis of the Druggable Families Based on Topological Features in the Protein-Protein Interaction Network

Journal: Letters in Drug Design & Discovery
Volume: 9 Issue: 4 Year: 2012 Page: 426-430
Author(s): Qi Yu, Jing-Fei Huang

Targetability of Human Disease Genes

Journal: Current Drug Discovery Technologies
Volume: 4 Issue: 1 Year: 2007 Page: 48-58
Author(s): Meena K. Sakharkar, Kishore R. Sakharkar

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