Search Result "substrate-based inhibitors"


Structural Bases for Substrate and Inhibitor Recognition by Matrix Metalloproteinases

Journal: Current Medicinal Chemistry
Volume: 15 Issue: 2 Year: 2008 Page: 2192-2222
Author(s): Loretta Aureli, Magda Gioia, Ilaria Cerbara, Susanna Monaco, Giovanni Francesco Fasciglione, Stefano Marini, Paolo Ascenzi, Alessandra Topai, Massimo Coletta

Research Article

Synthesis and Characterisation of Substrate-Based Peptides as Inhibitors of Histone Demethylase KDM4C

Journal: Protein & Peptide Letters
Volume: 23 Issue: 9 Year: 2016 Page: 772-776
Author(s): Simon D. Nielsen,Ulrike Leurs,Magnus Bergner,Silvia A. Barris,Kanchan Devkota,Kamilla Meyer,Daniella Iaria,Jack McCaughan,Brian Lohse,Jesper L. Kristensen,Rasmus P. Clausen

Recent Developments in the Design of Mechanism-based and Alternate Substrate Inhibitors of Serine Proteases

Journal: Current Topics in Medicinal Chemistry
Volume: 4 Issue: 1 Year: 2004 Page: 1203-1216
Author(s): Jiaying Zhong, William C. Groutas

Inhibitors of Farnesyltransferase and Geranylgeranyltransferase-I for Antitumor Therapy: Substrate-Based Design, Conformational Constraint and Biological Activity

Journal: Current Topics in Medicinal Chemistry
Volume: 3 Issue: 1 Year: 2003 Page: 1075-1093
Author(s): Christopher J. Dinsmore, Ian M. Bell

Kinetic Characterization of Factor Xa Binding Using a Quenched Fluorescent Substrate Based on the Reactive Site of Factor Xa Inhibitor from Bauhinia ungulata Seeds

Journal: Current Medicinal Chemistry
Volume: 10 Issue: 1 Year: 2003 Page: 1085-1093
Author(s): M. L.V. Oliva, S. A. Andrade, M. A. Juliano, R. C. Sallai, R. J. Torquato, M. U. Sampaio, V. J. Pott, C. A.M. Sampaio

Peptidomimetic Competitive Inhibitors of Protein Tyrosine Phosphatases

Journal: Current Pharmaceutical Design
Volume: 16 Issue: 2 Year: 2010 Page: 3101-3117
Author(s): Kui Shen, Lixin Qi, Lynn Stiff

Ribonucleotide Reductase: A Mechanistic Portrait of Substrate Analogues Inhibitors

Journal: Current Medicinal Chemistry
Volume: 17 Issue: 2 Year: 2010 Page: 2854-2872
Author(s): M.A.S. Perez, N.M.F.S.A. Cerqueira, P.A. Fernandes, M.J. Ramos

Design and Screening Strategies for α-Glucosidase Inhibitors Based on Enzymological Information

Journal: Current Topics in Medicinal Chemistry
Volume: 9 Issue: 1 Year: 2009 Page: 3-12
Author(s): Wataru Hakamata, Masaaki Kurihara, Haruhiro Okuda, Toshiyuki Nishio, Tadatake Oku

Testosterone Based Esters as Inhibitors of Aromatase (AR) and the use of the Substrate-Haem Complex Approach in the Rationalisation of the Inhibitory Activity of these Compounds

Journal: Letters in Drug Design & Discovery
Volume: 1 Issue: 4 Year: 2004 Page: 334-343
Author(s): Shaheen Adat, Sabbir Ahmed

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