Search Result "pxr"


Xenosensors CAR and PXR at Work: Impact on Statin Metabolism

Journal: Current Drug Metabolism
Volume: 12 Issue: 3 Year: 2011 Page: 300-311
Author(s): Maria Marino, Alessandra di Masi, Viviana Trezza, Valentina Pallottini, Fabio Polticelli, Paolo Ascenzi

Nuclear Receptors CAR and PXR in Metabolism and Elimination of Drugs

Journal: Current Pharmacogenomics
Volume: 1 Issue: 2 Year: 2003 Page: 75-85
Author(s): P. Honkakoski

Rat PXR Reporter-Gene Activity Correlates with the Induction of CYP3A in Rat Precision-Cut Liver Slices

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 8 Issue: 4 Year: 2005 Page: 341-346
Author(s): Xiaoming Cui, Ann Thomas, Diana Montgomery, Chunyan Gu, Richard A. Morrison, Ronald E. White, K. -C. Cheng

Structure and Function of the Human Nuclear Xenobiotic Receptor PXR

Journal: Current Drug Metabolism
Volume: 6 Issue: 4 Year: 2005 Page: 357-367
Author(s): V. E. Carnahan, M. R. Redinbo

Pregnane X Receptor (PXR) at the Crossroads of Human Metabolism and Disease

Journal: Current Drug Metabolism
Volume: 14 Issue: 3 Year: 2013 Page: 341-350
Author(s): Ioannis Koutsounas,Stamatios Theocharis,Efstratios Patsouris,Constantinos Giaginis

The Utility of Stable Cell Lines to Assess Species Differences in PXR Transactivation

Journal: Drug Metabolism Letters
Volume: 1 Issue: 2 Year: 2007 Page: 147-152
Author(s): Michael W. Sinz, Devin Pray, Judy Raucy

Post-translational and Post-transcriptional Modifications of Pregnane X Receptor (PXR) in Regulation of the Cytochrome P450 Superfamily

Journal: Current Drug Metabolism
Volume: 14 Issue: 10 Year: 2013 Page: 1059-1069
Author(s): Tomas Smutny,Sridhar Mani,Petr Pavek

Ligand Recognition by Drug-Activated Nuclear Receptors PXR and CAR: Structural, Site-Directed Mutagenesis and Molecular Modeling Studies

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 6 Issue: 8 Year: 2006 Page: 937-943
Author(s): Antti Poso, Paavo Honkakoski

Beyond CAR and PXR

Journal: Current Drug Metabolism
Volume: 6 Issue: 4 Year: 2005 Page: 385-397
Author(s): S. G. Dixit, R. G. Tirona, R. B. Kim

New Opportunities for Pregnane X Receptor (PXR) Targeting in Drug Development. Lessons from Enantio- and Species-Specific PXR Ligands Identified from A Discovery Library of Amino Acid Analogues

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 7 Issue: 6 Year: 2007 Page: 617-625
Author(s): Peter Wipf, Haibiao Gong, Jelena M. Janjic, Song Li, Billy W. Day, Wen Xie

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