Search Result "poorly permeable compounds"


A Systematic Evaluation of Solubility Enhancing Excipients to Enable the Generation of Permeability Data for Poorly Soluble Compounds in Caco-2 Model

Journal: Drug Metabolism Letters
Volume: 8 Issue: 2 Year: 2014 Page: 109-118
Author(s): Devang Shah,Sundeep Paruchury,Muralikrishna Matta,Gajendra Chowan,Murali Subramanian,Ajay Saxena,Matthew G. Soars,John Herbst,Roy Haskell,Punit Marathe,Sandhya Mandlekar

Design of Ester Prodrugs to Enhance Oral Absorption of Poorly Permeable Compounds: Challenges to the Discovery Scientist

Journal: Current Drug Metabolism
Volume: 4 Issue: 6 Year: 2003 Page: 461-485
Author(s): Kevin Beaumont, Robert Webster, Iain Gardner, Kevin Dack

Solubility and Permeability Measurement and Applications in Drug Discovery

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 13 Issue: 2 Year: 2010 Page: 101-111
Author(s): Philip S. Burton, Jay T. Goodwin

Artificial Membrane Assays to Assess Permeability

Journal: Current Drug Metabolism
Volume: 9 Issue: 9 Year: 2008 Page: 886-892
Author(s): Bernard Faller

Review Article

The Solubility-Permeability Interplay for Solubility-Enabling Oral Formulations

Journal: Current Drug Targets
Volume: 20 Issue: 14 Year: 2019 Page: 1434-1446
Author(s): Nidhi Nainwal,Ranjit Singh,Sunil Jawla,Vikas Anand Saharan

Mesoporous Materials and Nanocrystals for Enhancing the Dissolution Behavior of Poorly Water-soluble Drugs

Journal: Current Pharmaceutical Biotechnology
Volume: 14 Issue: 10 Year: 2013 Page: 926-938
Author(s): Helder A. Santos,Leena Peltonen,Tarja Limnell,Jouni Hirvonen

General Review Article

Bioavailability Enhancement of Poorly Soluble Drugs: The Holy Grail in Pharma Industry

Journal: Current Pharmaceutical Design
Volume: 25 Issue: 9 Year: 2019 Page: 987-1020
Author(s): Mamunur Rashid,Mohd Yaseen Malik,Sandeep K. Singh,Swati Chaturvedi,Jiaur R Gayen,Muhammad Wahajuddin

Mitochondrial Permeability Transition as Target of Anticancer Drugs

Journal: Current Pharmaceutical Design
Volume: 20 Issue: 2 Year: 2014 Page: 223-244
Author(s): Lisa Dalla Via, Aida N. Garcia-Argaez, Mariano Martinez-Vazquez, Silvia Grancara, Pamela Martinis, Antonio Toninello

Nanosuspension Technology: A Strategic Approach for Poorly Soluble Drugs

Journal: Nanoscience & Nanotechnology-Asia
Volume: 3 Issue: 1 Year: 2013 Page: 72-85
Author(s): Vijay Agarwal, Meenakshi Bajpai

Solubilization of Poorly Water-Soluble Drugs Using Solid Dispersions

Journal: Recent Patents on Drug Delivery & Formulation
Volume: 7 Issue: 2 Year: 2013 Page: 122-133
Author(s): Thao T.-D. Tran, Phuong H-L. Tran, Tran N. Khanh, Toi V. Van, Beom-Jin Lee

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