Search Result "pKa value"


Database Mining for pKa Prediction

Journal: Current Drug Discovery Technologies
Volume: 2 Issue: 4 Year: 2005 Page: 221-229
Author(s): Thierry Kogej, Sorel Muresan

Predicting the pKa of Small Molecules

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 14 Issue: 5 Year: 2011 Page: 307-327
Author(s): Matthias Rupp, Robert Korner, Igor V. Tetko

Research Article

Cyclization Effect on pKa of the Side Chain of Aspartic Acid in Dipeptides: A DFT Study

Journal: Letters in Organic Chemistry
Volume: 17 Issue: 5 Year: 2020 Page: 381-387
Author(s): Mohsen Sargolzaei,Majid Namayandeh Jorabchi

Scouting Novel Protein Kinase A (PKA) Inhibitors by Using a Consensus Docking-Based Virtual Screening Approach

Journal: Letters in Drug Design & Discovery
Volume: 6 Issue: 5 Year: 2009 Page: 327-336
Author(s): Nicola Zonta, Giorgio Cozza, Alessandra Gianoncelli, Oliver Korb, Thomas E. Exner, Flavio Meggio, Giuseppe Zagotto, Stefano Moro

Variation of pKa in the N-Terminal Tyrosine Side Chain in Octapeptide Analogs of Tendamistat Influences α-Amylase Inhibition

Journal: Protein & Peptide Letters
Volume: 14 Issue: 5 Year: 2007 Page: 497-501
Author(s): D. L. Heyl, B. Sethi, A. Rogalski, C. E. Bowen, M. Lawrence, L. Beitler, E. Harning, A. Hancer, S. Sreekumar, S. Fernandes

Calculation Methods for the Enhancement of Pharmaceutical Properties in Small Molecules: Estimating the Cationic pKa

Journal: Current Pharmaceutical Design
Volume: 19 Issue: 2 Year: 2013 Page: 4310-4315
Author(s): Ann R. Hermone, Rick Gussio

Research Article

Determination of pKa Values and Concurrent Analysis of Some Tricyclic Antidepressants in Acetonitrile-Water Mixtures

Journal: Current Pharmaceutical Analysis
Volume: 13 Issue: 2 Year: 2017 Page: 117-122
Author(s): Gulsen Guven,Senem Sanli,Nurullah Sanli

Determining Partition Coefficient (Log P), Distribution Coefficient (Log D) and Ionization Constant (pKa) in Early Drug Discovery

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 19 Issue: 6 Year: 2016 Page: 461-469
Author(s): Sonali S. Bharate,Vikas Kumar,Ram A. Vishwakarma

Research Article

Chromatographic and Surfactant Based Potentiometric Determination of Aqueous Dissociation Constant of Mupirocin

Journal: Current Analytical Chemistry
Volume: 16 Issue: 2 Year: 2020 Page: 158-165
Author(s): Natalija Nakov,Katerina Brezovska,Vasil Karchev,Jelena Acevska,Aneta Dimitrovska

Determination of The Ionization Constant of Local Anaesthetics in Organic Solvent-Water Media by The Spectrofluorimetric Method

Journal: Current Drug Therapy
Volume: 9 Issue: 4 Year: 2014 Page: 232-238
Author(s): S. Beniz Gunduz,Eda Ediz,Zeynep Altınordu

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