Search Result "pKa shift"


Database Mining for pKa Prediction

Journal: Current Drug Discovery Technologies
Volume: 2 Issue: 4 Year: 2005 Page: 221-229
Author(s): Thierry Kogej, Sorel Muresan

Scouting Novel Protein Kinase A (PKA) Inhibitors by Using a Consensus Docking-Based Virtual Screening Approach

Journal: Letters in Drug Design & Discovery
Volume: 6 Issue: 5 Year: 2009 Page: 327-336
Author(s): Nicola Zonta, Giorgio Cozza, Alessandra Gianoncelli, Oliver Korb, Thomas E. Exner, Flavio Meggio, Giuseppe Zagotto, Stefano Moro

Variation of pKa in the N-Terminal Tyrosine Side Chain in Octapeptide Analogs of Tendamistat Influences α-Amylase Inhibition

Journal: Protein & Peptide Letters
Volume: 14 Issue: 5 Year: 2007 Page: 497-501
Author(s): D. L. Heyl, B. Sethi, A. Rogalski, C. E. Bowen, M. Lawrence, L. Beitler, E. Harning, A. Hancer, S. Sreekumar, S. Fernandes

Determining Partition Coefficient (Log P), Distribution Coefficient (Log D) and Ionization Constant (pKa) in Early Drug Discovery

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 19 Issue: 6 Year: 2016 Page: 461-469
Author(s): Sonali S. Bharate,Vikas Kumar,Ram A. Vishwakarma

pKa, Zinc- and Serum Albumin-Binding of Curcumin and Two Novel Biologically- Active Chemically-Modified Curcumins

Journal: Current Medicinal Chemistry
Volume: 19 Issue: 25 Year: 2012 Page: 4367-4375
Author(s): Yu Zhang,Lorne M. Golub,Francis Johnson,Arnold Wishnia

The Attentional Set-Shifting Test Paradigm in Rats for the Screening of Novel Pro-Cognitive Compounds with Relevance for Cognitive Deficits in Schizophrenia

Journal: Current Pharmaceutical Design
Volume: 20 Issue: 3 Year: 2014 Page: 5060-5068
Author(s): Pascal Jean Denis Goetghebeur, Rebecca Dias

Simultaneous Determination of LogD, LogP, and pKa of Drugs by Using a Reverse Phase HPLC Coupled with a 96-Well Plate Auto Injector

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 12 Issue: 3 Year: 2009 Page: 250-257
Author(s): Po-Chang Chiang, Yiding Hu

Tumor Physiology and Charge Dynamics of Anticancer Drugs: Implications for Camptothecin-based Drug Development

Journal: Current Medicinal Chemistry
Volume: 18 Issue: 9 Year: 2011 Page: 1367-1372
Author(s): D. J. Adams, L. R. Morgan

Calculating the Protonation States of Proteins and Small Molecules: Implications to Ligand-Receptor Interactions

Journal: Current Computer-Aided Drug Design
Volume: 4 Issue: 3 Year: 2008 Page: 169-179
Author(s): Rooplekha Mitra, Radhey Shyam, Indranil Mitra, Maria A. Miteva, Emil Alexov

PDE10A Inhibitors: Novel Therapeutic Drugs for Schizophrenia

Journal: Current Pharmaceutical Design
Volume: 17 Issue: 2 Year: 2011 Page: 137-150
Author(s): Jan Kehler, Jacob Nielsen

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