Search Result "p110α"


Review Article

Triggering PIK3CA Mutations in PI3K/Akt/mTOR Axis: Exploration of Newer Inhibitors and Rational Preventive Strategies

Journal: Current Pharmaceutical Design
Volume: 22 Issue: 39 Year: 2016 Page: 6039-6054
Author(s): Vivek Asati,Sanjay K. Bharti,Debarshi Kar Mahapatra,Vikas Asati,Ashok K. Budhwani

Isoenzyme Selective Phosphoinositide 3-Kinase Inhibition: What do the Stones Kill?

Journal: Current Signal Transduction Therapy
Volume: 6 Issue: 3 Year: 2011 Page: 405-410
Author(s): Laszlo Buday, Szabolcs Sipeki

Research Article

Discovery of New Phosphoinositide 3-kinase Delta (PI3Kδ) Inhibitors via Virtual Screening using Crystallography-derived Pharmacophore Modelling and QSAR Analysis

Journal: Medicinal Chemistry
Volume: 15 Issue: 6 Year: 2019 Page: 588-601
Author(s): Mahmoud A. Al-Sha'er,Rua'a A. Al-Aqtash,Mutasem O. Taha

Progress in the Preclinical Discovery and Clinical Development of Class I and Dual Class I/IV Phosphoinositide 3-Kinase (PI3K) Inhibitors

Journal: Current Medicinal Chemistry
Volume: 18 Issue: 1 Year: 2011 Page: 2686-2714
Author(s): S. J. Shuttleworth, F. A. Silva, A. R.L. Cecil, C. D. Tomassi, T. J. Hill, F. I. Raynaud, P. A. Clarke, P. Workman

Advances in the Development of Class I Phosphoinositide 3-Kinase (PI3K) Inhibitors

Journal: Current Topics in Medicinal Chemistry
Volume: 16 Issue: 13 Year: 2016 Page: 1413-1426
Author(s): Dima A. Sabbah,Jian Hu,Haizhen A. Zhong

Isoform Selective Phosphoinositide 3-Kinase γ and δ Inhibitors and Their Therapeutic Potential

Journal: Recent Patents on Inflammation & Allergy Drug Discovery
Volume: 2 Issue: 1 Year: 2008 Page: 1-10
Author(s): Alessandra Ghigo, Emilio Hirsch

The PIK3CA Gene as a Mutated Target for Cancer Therapy

Journal: Current Cancer Drug Targets
Volume: 8 Issue: 8 Year: 2008 Page: 733-740
Author(s): John P. Gustin, David P. Cosgrove, Ben Ho Park

Role of PI3 Kinase Gamma in Excitation-Contraction Coupling and Heart Disease

Journal: Cardiovascular & Hematological Disorders-Drug Targets
Volume: 7 Issue: 4 Year: 2007 Page: 295-304
Author(s): Gavin Y. Oudit, Zamaneh Kassiri

The PKB/AKT Pathway in Cancer

Journal: Current Pharmaceutical Design
Volume: 16 Issue: 1 Year: 2010 Page: 34-44
Author(s): Amancio Carnero

Review Article

A Review of Stapled Peptides and Small Molecules to Inhibit Protein–Protein Interactions in Cancer

Journal: Current Medicinal Chemistry
Volume: 23 Issue: 27 Year: 2016 Page: 3025-3043
Author(s): Vidhya V. Iyer

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