Search Result "methylguanine"


Research Article

Effect of O6-Substituted Guanine Analogs on O6-methylguanine DNA-methyltransferase Expression and Glioblastoma Cells Viability

Journal: Medicinal Chemistry
Volume: 13 Issue: 1 Year: 2017 Page: 28-39
Author(s): Patrick-Denis St-Coeur, Marc Cormier, Veronique C. LeBlanc, Pier Jr. Morin, Mohamed Touaibia

Posttranslational Regulation of O6-Methylguanine-DNA Methyltransferase (MGMT) and New Opportunities for Treatment of Brain Cancers

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 16 Issue: 6 Year: 2016 Page: 455-464
Author(s): Kalkunte S. Srivenugopal, Amit Rawat, Suryakant K. Niture, Ameya Paranjpe, Chinavenmani Velu, Sanjay N. Venugopal, Hanumantha Rao Madala, Debasish Basak, Surendra R. Punganuru

Pharmacological Strategies to Increase the Antitumor Activity of Methylating Agents

Journal: Current Medicinal Chemistry
Volume: 9 Issue: 1 Year: 2002 Page: 1285-1301
Author(s): Lucio Tentori, Grazia Graziani

Review Article open access plus

Temozolomide Resistance: A Multifarious Review on Mechanisms BeyondO-6-Methylguanine-DNA Methyltransferase

Journal: CNS & Neurological Disorders - Drug Targets
Volume: 22 Issue: 6 Year: 2023 Page: 817-831
Author(s): Nanasaheb D. Thorat,Mallikarjuna Rao Chamallamudi

Strategies to Improve the Killing of Tumors Using Temozolomide: Targeting the DNA Repair Protein MGMT

Journal: Current Medicinal Chemistry
Volume: 19 Issue: 2 Year: 2012 Page: 3886-3892
Author(s): G. Jiang, L. -T. Li, Y. Xin, L. Zhang, Y. -Q. Liu, J. -N. Zheng

Research Article

O-6-methylguanine-DNA Methyltransferase Inhibits Gastric Carcinoma Cell Migration and Invasion by Downregulation of Matrix Metalloproteinase 2

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 16 Issue: 9 Year: 2016 Page: 1125-1132
Author(s): Chenglong Li,Li Deng,Hugang Shen,Qingyou Meng,Aimin Qian,Hongfei Sang,Jiazeng Xia,Xiaoqiang Li

Temozolomide: Mechanisms of Action, Repair and Resistance

Journal: Current Molecular Pharmacology
Volume: 5 Issue: 1 Year: 2012 Page: 102-114
Author(s): Jihong Zhang, Malcolm F.G. Stevens, Tracey D. Bradshaw

Temozolomide: An Update on Pharmacological Strategies to Increase its Antitumour Activity

Journal: Medicinal Chemistry Reviews - Online (Discontinued)
Volume: 1 Issue: 2 Year: 2004 Page: 141-150
Author(s): Lucio Tentori, Grazia Graziani

Recent Approaches to Improve the Antitumor Efficacy of Temozolomide

Journal: Current Medicinal Chemistry
Volume: 16 Issue: 2 Year: 2009 Page: 245-257
Author(s): Lucio Tentori, Grazia Graziani

Trends in Malignant Glioma Monoclonal Antibody Therapy

Journal: Current Cancer Therapy Reviews
Volume: 11 Issue: 2 Year: 2015 Page: 102-118
Author(s): Ivan Chekhonin,Olga Gurina

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