Search Result "mdr1-gene deficient mice"


Utility of Mdr1-Gene Deficient Mice in Assessing the Impact of P-glycoprotein on Pharmacokinetics and Pharmacodynamics in Drug Discovery and Development

Journal: Current Drug Metabolism
Volume: 4 Issue: 4 Year: 2003 Page: 272-291
Author(s): Cuiping Chen, Xingrong Liu, Bill J. Smith

Pharmacokinetic Interaction Between Verapamil and Methylxanthine Derivatives in Mice

Journal: Drug Metabolism Letters
Volume: 4 Issue: 1 Year: 2010 Page: 15-24
Author(s): Elzbieta Wyska

Pharmacogenetics of Drug Transporters and Its Impact on the Pharmacotherapy

Journal: Current Topics in Medicinal Chemistry
Volume: 4 Issue: 1 Year: 2004 Page: 1383-1396
Author(s): Toshiyuki Sakaeda, Tsutomu Nakamura, Katsuhiko Okumura

Pharmacogenetics of the Human MDR1 Multidrug Transporter

Journal: Current Pharmacogenomics
Volume: 2 Issue: 1 Year: 2004 Page: 1-11
Author(s): Caroline G. Lee, Samuel S. Chong, Edmund J. D.Lee

Treatment of MDR1 Mutant Dogs with Macrocyclic Lactones

Journal: Current Pharmaceutical Biotechnology
Volume: 13 Issue: 6 Year: 2012 Page: 969-986
Author(s): Joachim Geyer,Christina Janko

Vitamin D Deficiency: Universal Risk Factor for Multifactorial Diseases?

Journal: Current Drug Targets
Volume: 12 Issue: 1 Year: 2011 Page: 97-106
Author(s): Martin H. de Borst, Rudolf A. de Boer, Ronald P. Stolk, Joris P.J. Slaets, Bruce H.R. Wolffenbuttel, Gerjan Navis

P-Glycoprotein, but not Multidrug Resistance Protein 4, Plays a Role in the Systemic Clearance of Irinotecan and SN-38 in Mice

Journal: Drug Metabolism Letters
Volume: 4 Issue: 4 Year: 2010 Page: 195-201
Author(s): Michael Tagen, Yanli Zhuang, Fan Zhang, K. Elaine Harstead, Jun Shen, Paula Schaiquevich, Charles H. Fraga, John C. Panetta, Christopher M. Waters, Clinton F. Stewart

Toxicity in Animals: Target Species

Journal: Current Pharmaceutical Biotechnology
Volume: 13 Issue: 6 Year: 2012 Page: 952-968
Author(s): K. N. Woodward

Review Article

Effect of DNA Repair Deficiencies on the Cytotoxicity of Drugs Used in Cancer Therapy - A Review

Journal: Current Medicinal Chemistry
Volume: 21 Issue: 3 Year: 2014 Page: 3419-3454
Author(s): Jose Manuel Calderon-Montano, Estefania Burgos-Moron, Manuel Luis Orta, Miguel Lopez-Lazaro

RNA Interference-Based Gene Silencing in Mice: The Development of a Novel Therapeutical Strategy

Journal: Current Pharmaceutical Design
Volume: 11 Issue: 2 Year: 2005 Page: 3405-3419
Author(s): B. Spankuch, K. Strebhardt

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