Search Result "hit validation"


Enzyme Kinetics and Hit Validation in Fluorimetric Protease Assays

Journal: Current Topics in Medicinal Chemistry
Volume: 10 Issue: 3 Year: 2010 Page: 368-382
Author(s): Stephanie Ludewig, Markus Kossner, Markus Schiller, Knut Baumann, Tanja Schirmeister

NMR Screening and Hit Validation in Fragment Based Drug Discovery

Journal: Current Topics in Medicinal Chemistry
Volume: 11 Issue: 1 Year: 2011 Page: 43-67
Author(s): Ramon Campos-Olivas

Lead Generation - Enhancing the Success of Drug Discovery by Investing in the Hit to Lead Process

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 6 Issue: 1 Year: 2003 Page: 51-66
Author(s): Alexander Alanine, Matthias Nettekoven, Edward Roberts, Andrew W. Thomas

Efficient Optimization Strategy for Marginal Hits Active Against abl Tyrosine Kinases

Journal: Current Drug Discovery Technologies
Volume: 1 Issue: 3 Year: 2004 Page: 201-210
Author(s): Sergey E. Tkachenko, Ilya Okun, Konstantin V. Balakin, Charles E. Petersen, Yan A. Ivanenkov, Nikolay P. Savchuk, Andrey A. Ivashchenko

Identification and Validation of Hits from High Throughput Screens for CFTR Modulators

Journal: Current Pharmaceutical Design
Volume: 18 Issue: 5 Year: 2012 Page: 628-641
Author(s): Stan Pasyk, Steven Molinski, Wilson Yu, Paul D.W. Eckford, Christine E. Bear

Rational Prediction with Molecular Dynamics for Hit Identification

Journal: Current Topics in Medicinal Chemistry
Volume: 12 Issue: 18 Year: 2012 Page: 2002-2012
Author(s): Sara E. Nichols,Robert V. Swift,Rommie E. Amaro

A Collaborative Hit-to-Lead Investigation Leveraging Medicinal Chemistry Expertise with High Throughput Library Design, Synthesis and Purification Capabilities

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 9 Issue: 2 Year: 2006 Page: 123-130
Author(s): X. Yang, D. Parker, L. Whitehead, N. S. Ryder, B. Weidmann, M. Stabile-Harris, D. Kizer, M. McKinnon, A. Smellie, D. Powers

Selection, Application, and Validation of a Set of Molecular Descriptors for Nuclear Receptor Ligands

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 7 Issue: 5 Year: 2004 Page: 407-412
Author(s): Eugene L. Stewart, Peter J. Brown, James A. Bentley, Timothy M. Willson

Correlations and Validation

Ebook: Biophysics and Diving Decompression Phenomenology
Volume: 1 Year: 2016
Author(s): B.R. Wienke
Doi: 10.2174/9781681083193116010005

Target Immobilization and NMR Screening of Fragments in Early Drug Discovery

Journal: Current Topics in Medicinal Chemistry
Volume: 9 Issue: 1 Year: 2009 Page: 1736-1745
Author(s): Gregg Siegal, Johan G. Hollander

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