Search Result "hit and lead generation"
Lead Generation - Enhancing the Success of Drug Discovery by Investing in the Hit to Lead Process
Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 6 Issue: 1 Year: 2003 Page: 51-66
Author(s): Alexander Alanine, Matthias Nettekoven, Edward Roberts, Andrew W. Thomas
Trends in Hit-to-Lead: An Update
Ebook: Frontiers in Medicinal Chemistry
Volume: 3 Year: 2006
Author(s):
Doi: 10.2174/978160805206610603010653
Facts, Figures and Trends in Lead Generation
Journal: Current Topics in Medicinal Chemistry
Volume: 4 Issue: 6 Year: 2004 Page: 569-580
Author(s): Rebecca Deprez-Poulain, Benoit Deprez
Novel, Acidic CCR2 Receptor Antagonists: From Hit to Lead
Journal: Letters in Drug Design & Discovery
Volume: 4 Issue: 3 Year: 2007 Page: 185-191
Author(s): D. Zou, H.-X. Zhai, J. Eckman, P. Higgins, M. Gillard, L. Knerr, S. Carre, P. Pasau, P. Collart, J. Grassi
Components of Successful Lead Generation
Journal: Current Topics in Medicinal Chemistry
Volume: 5 Issue: 4 Year: 2005 Page: 421-439
Author(s): Andrew M. Davis, David J. Keeling, John Steele, Nicholas P. Tomkinson, Alan C. Tinker
Library Design Practices for Success in Lead Generation With Small Molecule Libraries
Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 6 Issue: 7 Year: 2003 Page: 649-660
Author(s): R. A. Goodnow Jr., W. Guba, W. Haap
A Collaborative Hit-to-Lead Investigation Leveraging Medicinal Chemistry Expertise with High Throughput Library Design, Synthesis and Purification Capabilities
Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 9 Issue: 2 Year: 2006 Page: 123-130
Author(s): X. Yang, D. Parker, L. Whitehead, N. S. Ryder, B. Weidmann, M. Stabile-Harris, D. Kizer, M. McKinnon, A. Smellie, D. Powers
Application and Utilization of Chemoinformatics Tools in Lead Generation and Optimization
Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 9 Issue: 2 Year: 2006 Page: 95-102
Author(s): N. Fotouhi, P. Gillespie, R. A. Goodnow, S.- S. So, Y. Han, L. E. Babiss
The Inhibition of Extended Spectrum β-Lactamases: Hits and Leads
Journal: Current Medicinal Chemistry
Volume: 21 Issue: 12 Year: 2014 Page: 1405-1434
Author(s): Davide Farina,Francesca Spyrakis,Alberto Venturelli,Simon Cross,Donatella Tondi,Maria Paola Costi
Efficient Optimization Strategy for Marginal Hits Active Against abl Tyrosine Kinases
Journal: Current Drug Discovery Technologies
Volume: 1 Issue: 3 Year: 2004 Page: 201-210
Author(s): Sergey E. Tkachenko, Ilya Okun, Konstantin V. Balakin, Charles E. Petersen, Yan A. Ivanenkov, Nikolay P. Savchuk, Andrey A. Ivashchenko