Search Result "hepatic clearance (CLh)"
Impact of Input Parameters on the Prediction of Hepatic Plasma Clearance Using the Well-Stirred Model
Journal: Current Drug Metabolism
Volume: 11 Issue: 7 Year: 2010 Page: 583-594
Author(s): Hong Wan, Peter Bold, Lars-Olof Larsson, Johan Ulander, Sheila Peters, Boel Lofberg, Anna-Lena Ungell, Mats Nagard, Antonio Llinas
Predicting Clearance in Humans from In Vitro Data
Journal: Current Topics in Medicinal Chemistry
Volume: 11 Issue: 4 Year: 2011 Page: 334-339
Author(s): R. Scott Obach
In Vitro Screening of Metabolic Clearance Using Two Concentration Points
Journal: Drug Metabolism Letters
Volume: 4 Issue: 4 Year: 2010 Page: 233-240
Author(s): Eric T. Williams, Nadia Farah, Robert D. Pelletier, W. George Lai
Comparative Pharmacokinetics and Metabolism Studies in Lean and Diet- Induced Obese Mice: An Animal Efficacy Model for 11β -Hydroxysteroid Dehydrogenase Type 1 (11β -HSD1) Inhibitors
Journal: Drug Metabolism Letters
Volume: 5 Issue: 1 Year: 2011 Page: 55-63
Author(s): Mengmeng Wang, Xianbin Tian, Louis Leung, Jianyao Wang, Nicole Houvig, Jason Xiang, Eddine Saiah, Seung Hahm, Vipin Suri, Xin Xu
Scaling In Vivo Pharmacokinetics from In Vitro Metabolic Stability Data in Drug Discovery
Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 13 Issue: 2 Year: 2010 Page: 159-169
Author(s): Wendy Klopf, Philip Worboys
The Impact of In Vitro Binding on In Vitro - In Vivo Extrapolations, Projections of Metabolic Clearance and Clinical Drug-Drug Interactions
Journal: Current Drug Metabolism
Volume: 7 Issue: 3 Year: 2006 Page: 251-264
Author(s): K. Grime, R. J. Riley
Selective Inhibitors of Hepatitis B Virus Replication
Journal: Current Medicinal Chemistry - Anti-Infective Agents
Volume: 2 Issue: 3 Year: 2003 Page: 227-240
Author(s): Chunxiao Ying, Erik De Clercq, Johan Neyts
Metabolism and Disposition of the Antiviral Nucleoside Analogue AM365 in the Isolated Perfused Rat Liver
Journal: Current Drug Metabolism
Volume: 6 Issue: 5 Year: 2005 Page: 487-493
Author(s): J. Wang, R. L. Nation, A. M. Evans, S. Cox, D. Shackleford
Drug Design Tools - In Silico, In Vitro and In Vivo ADME/PK Prediction and Interpretation: Is PK in Monkey An Essential Part of a Good Human PK Prediction?
Journal: Current Topics in Medicinal Chemistry
Volume: 11 Issue: 4 Year: 2011 Page: 351-357
Author(s): Natilie A. Hosea
How New Drugs are Developed: Kinetics Evaluations
Ebook: Medicinal Chemistry - Fusion of Traditional and Western Medicine
Volume: 1 Year: 2013
Author(s): Robert E. Smith
Doi: 10.2174/9781608051496113010005