Search Result "free/unbound drug concentration"
Insight into Tissue Unbound Concentration: Utility in Drug Discovery and Development
Journal: Current Drug Metabolism
Volume: 14 Issue: 3 Year: 2013 Page: 324-340
Author(s): T. Thanga Mariappan,Sandhya Mandlekar,Punit Marathe
In Silico Prediction of Brain Exposure: Drug Free Fraction, Unbound Brain to Plasma Concentration Ratio and Equilibrium Half-Life
Journal: Current Topics in Medicinal Chemistry
Volume: 13 Issue: 7 Year: 2013 Page: 813-820
Author(s): Morena Spreafico, Matthew P. Jacobson
Do We Need to Optimize Plasma Protein and Tissue Binding in Drug Discovery?
Journal: Current Topics in Medicinal Chemistry
Volume: 11 Issue: 4 Year: 2011 Page: 450-466
Author(s): Xingrong Liu, Cuiping Chen, Cornelis E.C.A. Hop
Plasma Protein Binding in Drug Discovery and Development
Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 13 Issue: 2 Year: 2010 Page: 170-187
Author(s): Monique L. Howard, John J. Hill, Gerald R. Galluppi, Matthew A. McLean
Methodologies to Assess Brain Drug Delivery in Lead Optimization
Journal: Current Topics in Medicinal Chemistry
Volume: 9 Issue: 2 Year: 2009 Page: 148-162
Author(s): Margareta Hammarlund-Udenaes, Ulf Bredberg, Markus Friden
Drug-Drug Interaction Potential of Remimazolam: CYP 450, Transporters, and Protein Binding
Journal: Current Drug Metabolism
Volume: 25 Issue: 4 Year: 2024 Page: 266-275
Author(s):
Intervention Guidelines for Neonatal Hyperbilirubinemia: An Evidence Based Quagmire
Journal: Current Pharmaceutical Design
Volume: 15 Issue: 2 Year: 2009 Page: 2939-2945
Author(s): Richard P. Wennberg, Charles E. Ahlfors, Aleksandr Y. Aravkin
Displacement of Drugs from Human Serum Albumin: From Molecular Interactions to Clinical Significance
Journal: Current Medicinal Chemistry
Volume: 24 Issue: 18 Year: 2017 Page: 1930-1947
Author(s): Hrvoje Rimac,Željko Debeljak,Mirza BojiÄ,Larisa Miller
The Role of Unbound Drug in Pharmacokinetics/Pharmacodynamics and in Therapy
Journal: Current Pharmaceutical Design
Volume: 12 Issue: 8 Year: 2006 Page: 977-987
Author(s): Rosario Calvo, John C. Lukas, Monica Rodriguez, Nerea Leal, Elena Suarez
Release of Antithrombotic Drugs from Alginate Gel Beads
Journal: Current Drug Delivery
Volume: 7 Issue: 4 Year: 2010 Page: 297-302
Author(s): Erik Jamstorp, Aase Bodin, Paul Gatenholm, Anders Jeppsson, Maria Stromme