Search Result "false positive hit"
False Positives in the Early Stages of Drug Discovery
Journal: Current Medicinal Chemistry
Volume: 17 Issue: 3 Year: 2010 Page: 4231-4255
Author(s): R. Sink, S. Gobec, S. Pecar, A. Zega
NMR-Based Quality Control Approach for the Identification of False Positives and False Negatives in High Throughput Screening
Journal: Current Drug Discovery Technologies
Volume: 3 Issue: 2 Year: 2006 Page: 115-124
Author(s): Claudio Dalvit, Dannica Caronni, Nicola Mongelli, Marina Veronesi, Anna Vulpetti
Enzyme Kinetics and Hit Validation in Fluorimetric Protease Assays
Journal: Current Topics in Medicinal Chemistry
Volume: 10 Issue: 3 Year: 2010 Page: 368-382
Author(s): Stephanie Ludewig, Markus Kossner, Markus Schiller, Knut Baumann, Tanja Schirmeister
Using IMAP Technology to Identify Kinase Inhibitors: Comparison with a Substrate Depletion Approach and Analysis of the Nature of False Positives
Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 8 Issue: 4 Year: 2005 Page: 319-325
Author(s): P. Singh, B. Lillywhite, C. Bannaghan, P. Broad
Efficient Optimization Strategy for Marginal Hits Active Against abl Tyrosine Kinases
Journal: Current Drug Discovery Technologies
Volume: 1 Issue: 3 Year: 2004 Page: 201-210
Author(s): Sergey E. Tkachenko, Ilya Okun, Konstantin V. Balakin, Charles E. Petersen, Yan A. Ivanenkov, Nikolay P. Savchuk, Andrey A. Ivashchenko
NMR Screening and Hit Validation in Fragment Based Drug Discovery
Journal: Current Topics in Medicinal Chemistry
Volume: 11 Issue: 1 Year: 2011 Page: 43-67
Author(s): Ramon Campos-Olivas
Lead Generation - Enhancing the Success of Drug Discovery by Investing in the Hit to Lead Process
Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 6 Issue: 1 Year: 2003 Page: 51-66
Author(s): Alexander Alanine, Matthias Nettekoven, Edward Roberts, Andrew W. Thomas
Target Immobilization and NMR Screening of Fragments in Early Drug Discovery
Journal: Current Topics in Medicinal Chemistry
Volume: 9 Issue: 1 Year: 2009 Page: 1736-1745
Author(s): Gregg Siegal, Johan G. Hollander
Rational Prediction with Molecular Dynamics for Hit Identification
Journal: Current Topics in Medicinal Chemistry
Volume: 12 Issue: 18 Year: 2012 Page: 2002-2012
Author(s): Sara E. Nichols,Robert V. Swift,Rommie E. Amaro
The Identification, Characterization and Optimization of Small Molecule Probes of Cysteine Proteases: Experiences of the Penn Center for Molecular Discovery with Cathepsin B and Cathepsin L
Journal: Current Topics in Medicinal Chemistry
Volume: 9 Issue: 1 Year: 2009 Page: 1206-1216
Author(s): Donna M. Huryn, Amos B. Smith III