Search Result "early adme"


Advancements in Predictive In Silico Models for ADME

Journal: Current Chemical Biology
Volume: 2 Issue: 3 Year: 2008 Page: 215-228
Author(s): Kamaldeep K. Chohan, Stuart W. Paine, Nigel J. Waters

Pharmacokinetic Properties and In Silico ADME Modeling in Drug Discovery

Journal: Medicinal Chemistry
Volume: 9 Issue: 2 Year: 2013 Page: 163-176
Author(s): Kathia M. Honorio,Tiago L. Moda,Adriano D. Andricopulo

ADME Optimization and Toxicity Assessment in Early- and Late-Phase Drug Discovery

Journal: Current Topics in Medicinal Chemistry
Volume: 9 Issue: 1 Year: 2009 Page: 965-980
Author(s): Gary W. Caldwell, Zhengyin Yan, Weimin Tang, Malini Dasgupta, Becki Hasting

Early ADME in Support of Drug Discovery: The Role of Metabolic Stability Studies

Journal: Current Drug Metabolism
Volume: 1 Issue: 3 Year: 2000 Page: 215-241
Author(s): Thomas N. Thompson

In Vitro ADME Medium/High-Throughput Screening in Drug Preclinical Development

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 6 Issue: 9 Year: 2006 Page: 1053-1062
Author(s): A. Lahoz, L. Gombau, M. T. Donato, J. V Castell, M. J. Gomez-Lechon

Optimization of Important Early ADME(T) Parameters of NADPH Oxidase-4 Inhibitor Molecules

Journal: Medicinal Chemistry
Volume: 8 Issue: 2 Year: 2012 Page: 174-181
Author(s): Gabor Borbely, Monika Huszar, Attila Varga, Krisztina Futosi, Attila Mocsai, Laszlo Orfi, Miklos Idei, Jozsef Mandl,Gyorgy Keri, Tibor Vantus

The Utility of Semi-Automating Multiplexed Assays for ADME/Tox Applications

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 14 Issue: 8 Year: 2011 Page: 658-668
Author(s): Brad Larson, Peter Banks, Sarah Shultz, Mary Sobol, James J. Cali

In-Silico ADME Models: A General Assessment of their Utility in Drug Discovery Applications

Journal: Current Topics in Medicinal Chemistry
Volume: 11 Issue: 4 Year: 2011 Page: 358-381
Author(s): M. Paul Gleeson, Anne Hersey, Supa Hannongbua

Strategy of Utilizing In Vitro and In Vivo ADME Tools for Lead Optimization and Drug Candidate Selection

Journal: Current Topics in Medicinal Chemistry
Volume: 5 Issue: 1 Year: 2005 Page: 1033-1038
Author(s): Suresh K. Balani, Gerald T. Miwa, Liang-Shang Gan, Jing-Tao Wu, Frank W. Lee

In Silico Predictions of ADME-Tox Properties: Drug Absorption

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 14 Issue: 5 Year: 2011 Page: 339-361
Author(s): Tessy Geerts, Yvan Vander Heyden

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