Search Result "constitutively active mutants"
A Phenotypic Screen for Small-Molecule Inhibitors of Constitutively Active Mutant Thrombopoietin Receptor Implicated in Myeloproliferative Neoplasms
Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 19 Issue: 10 Year: 2016 Page: 824-833
Author(s): Anna Ngo,Ann Zhufang Koay,Christian Pecquet,Carmen C. Diaconu,Yasmine Ould-Amer,Qiwei Huang,Congbao Kang,Anders Poulsen,May Ann Lee,David Jenkins,Andrew Shiau,Stefan N. Constantinescu,Meng Ling Choong
Serotonin2c Receptor Constitutive Activity: In vivo Direct and Indirect Evidence and Functional Significance
Journal: Central Nervous System Agents in Medicinal Chemistry
Volume: 13 Issue: 2 Year: 2013 Page: 98-107
Author(s): Sylvia Navailles,Mélanie Lagière,Martin Guthrie,Philippe De Deurwaerdère
Insight into Discovery of Next Generation Reversible TMLR Inhibitors Targeting EGFR Activating and Drug Resistant T790M Mutants
Journal: Current Cancer Drug Targets
Volume: 17 Issue: 7 Year: 2017 Page: 617-636
Author(s): Subhash Mohan Agarwal,Divyani Pal,Mansi Gupta,Ravi Saini
Novel Polymethoxylated Chalcones as Potential Compounds Against KRAS-Mutant Colorectal Cancers
Journal: Current Pharmaceutical Design
Volume: 26 Issue: 14 Year: 2020 Page: 1622-1633
Author(s): Alaa Mahmoud,Dana Elkhalifa,Feras Alali,Ala-Eddin Al Moustafa,Ashraf Khalil
Temporal Expression of Mutant TDP-43 Correlates with Early Amyotrophic Lateral Sclerosis Phenotype and Motor Weakness
Journal: Current Neurovascular Research
Volume: 15 Issue: 1 Year: 2018 Page: 3-9
Author(s): Qihua Chen,Jinxia Zhou,Cao Huang,Bo Huang,Fangfang Bi,Hongxia Zhou,Bo Xiao
Molecular Effects of the CTG Repeats in Mutant Dystrophia Myotonica Protein Kinase Gene
Journal: Current Genomics
Volume: 9 Issue: 8 Year: 2008 Page: 509-516
Author(s): Beatriz Llamusi, Ruben Artero
Constitutively Activated G Protein-Coupled Receptors: A Novel Approach to CNS Drug Discovery
Journal: Current Drug Targets - CNS & Neurological Disorders
Volume: 1 Issue: 1 Year: 2002 Page: 105-121
Author(s): Frederique D.P. Menzaghi, Dominic P. Behan, Derek T. Chalmers
Mutant Epidermal Growth Factor Receptors as Targets for Cancer Therapy
Journal: Current Cancer Drug Targets
Volume: 2 Issue: 2 Year: 2002 Page: 91-102
Author(s): I. A.J. Lorimer
Computer-Aided Drug Design for Cancer-Causing H-Ras p21 Mutant Protein
Journal: Letters in Drug Design & Discovery
Volume: 6 Issue: 1 Year: 2009 Page: 14-20
Author(s): Mannu Jayakanthan, Gulshan Wadhwa, Thangavel Madhan Mohan, Loganathan Arul, Ponnusamy Balasubramanian, Durai Sundar
The Allosteric Properties of Hemoglobin: Insights from Natural and Site Directed Mutants
Journal: Current Protein & Peptide Science
Volume: 7 Issue: 1 Year: 2006 Page: 17-45
Author(s): Andrea Bellelli, Maurizio Brunori, Adriana E. Miele, Gianna Panetta, Beatrice Vallone