Search Result "Simple Reversible DDI Prediction Model"


The Use of HepaRG and Human Hepatocyte Data in Predicting CYP Induction Drug-Drug Interactions via Static Equation and Dynamic Mechanistic Modelling Approaches

Journal: Current Drug Metabolism
Volume: 11 Issue: 1 Year: 2010 Page: 870-885
Author(s): Ken Grime, Douglas D. Ferguson, Robert J. Riley

Physiological Approaches to the Prediction of Drug-Drug Interactions in Study Populations

Journal: Current Drug Metabolism
Volume: 4 Issue: 5 Year: 2003 Page: 347-356
Author(s): J. Y. Chien, M. A. Mohutsky, S. A. Wrighton

Physiologically based in vitro Models to Predict the Oral Dissolution and Absorption of a Solid Drug Delivery system

Journal: Current Drug Metabolism
Volume: 16 Issue: 9 Year: 2015 Page: 777-806
Author(s): Ziqiang Li,Xin He

Emerging In Vitro Tools to Evaluate Cytochrome P450 and Transporter-Mediated Drug-Drug Interactions

Journal: Current Drug Discovery Technologies
Volume: 7 Issue: 3 Year: 2010 Page: 199-222
Author(s): Cormac Concannon, Desmond A. Hennelly, Simon Noott, Dipak K. Sarker, Chuang Lu, Mingxiang Liao, Lawrence Cohen, Cindy Q. Xia

Methods for Predicting In Vivo Pharmacokinetics Using Data from In Vitro Assays

Journal: Current Drug Metabolism
Volume: 9 Issue: 9 Year: 2008 Page: 940-951
Author(s): J. Brian Houston, Aleksandra Galetin

Maximal Inhibition of Intestinal First-Pass Metabolism as a Pragmatic Indicator of Intestinal Contribution to the Drug-Drug Interactions for CYP3A4 Cleared Drugs

Journal: Current Drug Metabolism
Volume: 8 Issue: 7 Year: 2007 Page: 685-693
Author(s): Aleksandra Galetin, Laura K. Hinton, Howard Burt, R. Scott Obach, J. Brian Houston

In-Silico ADME Models: A General Assessment of their Utility in Drug Discovery Applications

Journal: Current Topics in Medicinal Chemistry
Volume: 11 Issue: 4 Year: 2011 Page: 358-381
Author(s): M. Paul Gleeson, Anne Hersey, Supa Hannongbua

The Challenges Involved in Modeling Toxicity Data In Silico: A Review

Journal: Current Pharmaceutical Design
Volume: 18 Issue: 9 Year: 2012 Page: 1266-1291
Author(s): M. Paul Gleeson, Sandeep Modi, Andreas Bender, Richard L. Marchese Robinson, Johannes Kirchmair, Malinee Promkatkaew, Supa Hannongbua, Robert C. Glen

Simple and General Criterion for “in silico” Screening of Candidate HIV Drugs

Journal: Current Pharmaceutical Biotechnology
Volume: 14 Issue: 5 Year: 2013 Page: 561-569
Author(s): Nevena Veljkovic,Sanja Glisic,Jelena Prljic,Vladimir Perovic,Veljko Veljkovic

QSAR Study on Pyridinone Derivatives as HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitor: A Mixed Approach

Journal: Medicinal Chemistry
Volume: 3 Issue: 3 Year: 2007 Page: 227-232
Author(s): P. Vasanthanathan, M. Lakshmi, A. Raghuram Rao

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