Search Result "Rat PXR"


Rat PXR Reporter-Gene Activity Correlates with the Induction of CYP3A in Rat Precision-Cut Liver Slices

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 8 Issue: 4 Year: 2005 Page: 341-346
Author(s): Xiaoming Cui, Ann Thomas, Diana Montgomery, Chunyan Gu, Richard A. Morrison, Ronald E. White, K. -C. Cheng

The Utility of Stable Cell Lines to Assess Species Differences in PXR Transactivation

Journal: Drug Metabolism Letters
Volume: 1 Issue: 2 Year: 2007 Page: 147-152
Author(s): Michael W. Sinz, Devin Pray, Judy Raucy

Xenosensors CAR and PXR at Work: Impact on Statin Metabolism

Journal: Current Drug Metabolism
Volume: 12 Issue: 3 Year: 2011 Page: 300-311
Author(s): Maria Marino, Alessandra di Masi, Viviana Trezza, Valentina Pallottini, Fabio Polticelli, Paolo Ascenzi

Nuclear Receptors CAR and PXR in Metabolism and Elimination of Drugs

Journal: Current Pharmacogenomics
Volume: 1 Issue: 2 Year: 2003 Page: 75-85
Author(s): P. Honkakoski

Structure and Function of the Human Nuclear Xenobiotic Receptor PXR

Journal: Current Drug Metabolism
Volume: 6 Issue: 4 Year: 2005 Page: 357-367
Author(s): V. E. Carnahan, M. R. Redinbo

Post-translational and Post-transcriptional Modifications of Pregnane X Receptor (PXR) in Regulation of the Cytochrome P450 Superfamily

Journal: Current Drug Metabolism
Volume: 14 Issue: 10 Year: 2013 Page: 1059-1069
Author(s): Tomas Smutny,Sridhar Mani,Petr Pavek

Ligand Recognition by Drug-Activated Nuclear Receptors PXR and CAR: Structural, Site-Directed Mutagenesis and Molecular Modeling Studies

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 6 Issue: 8 Year: 2006 Page: 937-943
Author(s): Antti Poso, Paavo Honkakoski

New Opportunities for Pregnane X Receptor (PXR) Targeting in Drug Development. Lessons from Enantio- and Species-Specific PXR Ligands Identified from A Discovery Library of Amino Acid Analogues

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 7 Issue: 6 Year: 2007 Page: 617-625
Author(s): Peter Wipf, Haibiao Gong, Jelena M. Janjic, Song Li, Billy W. Day, Wen Xie

Research Article

Transactivation Assays that Identify Indirect and Direct Activators of Human Pregnane X Receptor (PXR, NR1I2) and Constitutive Androstane Receptor (CAR, NR1I3)

Journal: Drug Metabolism Letters
Volume: 11 Issue: 2 Year: 2017 Page: 128-137
Author(s): Marija Pinne,Elsa Ponce,Judy L. Raucy

Activation of CAR and PXR by Dietary, Environmental and Occupational Chemicals Alters Drug Metabolism, Intermediary Metabolism, and Cell Proliferation

Journal: Current Pharmacogenomics and Personalized Medicine
Volume: 7 Issue: 2 Year: 2009 Page: 81-105
Author(s): Juan P. Hernandez, Linda C. Mota, William S. Baldwin

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