Search Result "Pyrophosphate Bioisosteres"


Progress in the Development of Pyrophosphate Bioisosteres: Synthesis and Biomedical Potential of 1-Fluoro- and 1,1-Difluoromethylene-1,1-bisphosphonates

Journal: Current Organic Chemistry
Volume: 18 Issue: 11 Year: 2014 Page: 1491-1512
Author(s): Vadim D. Romanenko,Valery P. Kukhar

Recent Advances in the Development of Undecaprenyl Pyrophosphate Synthase Inhibitors as Potential Antibacterials

Journal: Current Medicinal Chemistry
Volume: 23 Issue: 5 Year: 2016 Page: 464-482
Author(s): Marko Jukic,Kaja Rozman,Stanislav Gobec

Review Article

Oxocarbon Acids and their Derivatives in Biological and MedicinalChemistry

Journal: Current Medicinal Chemistry
Volume: 31 Issue: 10 Year: 2024 Page: 1172-1213
Author(s): John F. Honek

Investigation of Bioisosteric Effects on the Interaction of Substrates/ Inhibitors with the Methionyl-tRNA Synthetase from Escherichia coli

Journal: Medicinal Chemistry
Volume: 1 Issue: 3 Year: 2005 Page: 227-237
Author(s): M. D. Vaughan, P. B. Sampson, E. Daub, J. F. Honek

2-Hydroxy-1-oxo-1,2-dihydroisoquinoline-3-carboxylic Acid with Inbuilt β-N-Hydroxy-γ-keto-acid Pharmacophore as HCV NS5B Polymerase Inhibitors

Journal: Current Medicinal Chemistry
Volume: 19 Issue: 4 Year: 2012 Page: 613-624
Author(s): R. R. Deore, G. S. Chen, C. -S. Chen, P. -T. Chang, M. -H. Chuang, T. -R. Chern, H. -C. Wang, J. -W. Chern

Review Article

α-Heteroatom-substituted gem-Bisphosphonates: Advances in the Synthesis and Prospects for Biomedical Application

Journal: Current Organic Chemistry
Volume: 23 Issue: 5 Year: 2019 Page: 530-615
Author(s): Vadim D. Romanenko

Advances in the Synthesis of Functional α-Organyl gem-Bisphosphonates for Biomedical Applications

Ebook: Advances in Organic Synthesis
Volume: 12 Year: 2018
Author(s): Vadim D. Romanenko
Doi: 10.2174/9781681086804118120007

Mechanisms of bacterial acetohydroxyacid synthase (ahas) and specific inhibitors of Mycobacterium tuberculosis ahas as potential drug candidates against tuberculosis

Journal: Current Drug Targets
Volume: 16 Issue: 7 Year: 2015 Page: 689-699
Author(s): Kunal Gokhale,Bhargav Tilak

Phenyldihydroxypyrimidines as HCV NS5B RNA Dependent RNA Polymerase Inhibitors. Part I: Amides and Ureas

Journal: Letters in Drug Design & Discovery
Volume: 2 Issue: 6 Year: 2005 Page: 451-455
Author(s): B. Crescenzi, M. Poma, J. M. Ontoria, A. Marchetti, E. Nizi, V. G. Matassa, C. Gardelli

Recent Advances in Discovery and Development of Promising Therapeutics against Hepatitis C Virus NS5B RNA-Dependent RNA Polymerase

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 5 Issue: 1 Year: 2005 Page: 1103-1112
Author(s): Jim Z. Wu, Nanhua Yao, Michelle Walker, Zhi Hong

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