Search Result "P450-mediated hepatotox-icity"
Diallyl Sulfide: Potential Use in Novel Therapeutic Interventions in Alcohol, Drugs, and Disease Mediated Cellular Toxicity by Targeting Cytochrome P450 2E1
Journal: Current Drug Metabolism
Volume: 16 Issue: 6 Year: 2015 Page: 486-503
Author(s): PSS Rao,Narasimha M. Midde,Duane D. Miller,Subhash Chauhan,Anil Kumar,Santosh Kumar
Inhibition of Cytochrome P450 1A2-Mediated Metabolism and Production of Reactive Oxygen Species by Heme Oxygenase-1 in Rat Liver Microsomes
Journal: Drug Metabolism Letters
Volume: 5 Issue: 1 Year: 2011 Page: 6-16
Author(s): James R. Reed, George F. Cawley, Wayne L. Backes
Role of Cyclic Tertiary Amine Bioactivation to Reactive Iminium Species: Structure Toxicity Relationship
Journal: Current Drug Metabolism
Volume: 12 Issue: 1 Year: 2011 Page: 35-50
Author(s): Lucija Peterlin Masic
Mechanism-Based Inhibitors from Phytomedicine: Risks of Hepatotoxicity and their Potential Hepatotoxic Substructures
Journal: Current Drug Metabolism
Volume: 17 Issue: 10 Year: 2016 Page: 971-991
Author(s): Lili Wang,Xin He,Chunhuan Jin,Gregory Ondieki
Metabolism is not a Major Contributor to the Toxicity of Piperaquine, a Long-acting Antimalarial Agent in Artemisinin-based Combination Therapy
Journal: Current Drug Metabolism
Volume: 22 Issue: 10 Year: 2021 Page: 824-834
Author(s): Liyuan Zhang,Zhaohua Liu,Yunrui Zhang,Yuewu Xie,Jie Xing
Mechanism-based Inhibition of CYP450: An Indicator of Drug-induced Hepatotoxicity
Journal: Current Drug Metabolism
Volume: 14 Issue: 9 Year: 2013 Page: 921-945
Author(s): Shan Feng,Xin He
Metabolomics in Drug Intolerance
Journal: Current Drug Metabolism
Volume: 10 Issue: 9 Year: 2009 Page: 947-955
Author(s): Inmaculada Andreu, Cristobalina Mayorga, Miguel A. Miranda
Reactive Metabolites in Early Drug Development: Predictive In vitro Tools
Journal: Current Medicinal Chemistry
Volume: 22 Issue: 4 Year: 2015 Page: 538-550
Author(s): Olavi Pelkonen, Markku Pasanen, Ari Tolonen, Mikko Koskinen, Jukka Hakkola, Khaled Abass, Jaana Laine, Merja Hakkinen, Risto Juvonen, Seppo Auriola, Markus Storvik, Pasi Huuskonen, Timo Rousu, Maiju Rahikkala
In Vitro Human Hepatocyte-Based Experimental Systems for the Evaluation of Human Drug Metabolism, Drug-Drug Interactions, and Drug Toxicity in Drug Development
Journal: Current Topics in Medicinal Chemistry
Volume: 14 Issue: 11 Year: 2014 Page: 1325-1338
Author(s): Albert P. Li
Human-Based In Vitro Experimental Systems for the Evaluation of Human Drug Safety
Journal: Current Drug Safety
Volume: 2 Issue: 3 Year: 2007 Page: 193-199
Author(s): Albert P. Li