Search Result "MCH R1 antagonist"


Development of Melanin Concentrating Hormone Receptor R1 Antagonists for the Pharmacological Treatment of Obesity

Ebook: Anti-Obesity Drug Discovery and Development
Volume: 1 Year: 2011
Author(s): Gildardo Rivera,Antonio Monge,Virgilio Bocanegra-Garcia
Doi: 10.2174/978160805163211101010200

Biphenyl Amides and Isosteres as MCH R1 Antagonists

Journal: Current Topics in Medicinal Chemistry
Volume: 7 Issue: 1 Year: 2007 Page: 1455-1470
Author(s): Donald L. Hertzog, David R. Witty

Structural Analysis of 2-Piperidin-4-yl-Actamide Derivatives for hERG Blocking and MCH R1 Antagonistic Activities

Journal: Current Drug Discovery Technologies
Volume: 9 Issue: 1 Year: 2012 Page: 25-38
Author(s): N. S. Hari Narayana Moorthy, Maria J. Ramos, Pedro A. Fernandes

Melanin Concentrating Hormone Receptor Antagonists as Antiobesity Agents: From M2 to MCHR-1

Journal: Current Topics in Medicinal Chemistry
Volume: 7 Issue: 1 Year: 2007 Page: 1440-1454
Author(s): Mark D. McBriar

Melanin-Concentrating Hormone Receptor 1 Antagonists: A New Perspective for the Pharmacologic Treatment of Obesity

Journal: Current Medicinal Chemistry
Volume: 15 Issue: 1 Year: 2008 Page: 1025-1043
Author(s): Gildardo Rivera, Virgilio Bocanegra-Garcia, Silvia Galiano, Nuria Cirauqui, Javier Ceras, Silvia Perez, Ignacio Aldana, Antonio Monge

Orphan GPCR Ligands Related to Obesity

Journal: Current Medicinal Chemistry - Central Nervous System Agents
Volume: 3 Issue: 2 Year: 2003 Page: 101-120
Author(s): Yukio Fujisawa, Masaaki Mori, Tetsuya Ohtaki, Shuji Hinuma, Masahiko Fujino

Lead Optimization of Melanin Concentrating Hormone Receptor 1 Antagonists with low hERG Channel Activity

Journal: Current Topics in Medicinal Chemistry
Volume: 8 Issue: 1 Year: 2008 Page: 1152-1157
Author(s): Andrew S. Judd, Andrew J. Souers, Philip R. Kym

QSAR and Pharmacophore Analysis of a Series of Piperidinyl Urea Derivatives as hERG Blockers and H3 Antagonists

Journal: Current Drug Discovery Technologies
Volume: 10 Issue: 1 Year: 2013 Page: 47-58
Author(s): N. S. Hari Narayana Moorthy, Maria J. Ramos, Pedro A. Fernandes

Molecular Modulation of Muscarinic Antagonists. Synthesis and Pharmacological Profile of 2,2-diphenyl-2-ethylthioacetic and 3,3-diphenyl-3- ethylthiopropionic Acid Derivatives Characterized by a Dipeptide Spacer

Journal: Letters in Drug Design & Discovery
Volume: 1 Issue: 2 Year: 2004 Page: 91-96
Author(s): S. Scapecchi, C. Martelli, P. Angeli, C. Bellucci, M. Buccioni, S. Dei, F. Gualtieri, G. Marucci, R. Matucci, M. N. Romanelli

Review Article

Obesity: Current Treatment and Future Horizons

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 17 Issue: 1 Year: 2017 Page: 51-61
Author(s): Ziad Omran

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