Search Result "Kinase-inactive mutants"


Review Article

Targeting Mutant KRAS for Anticancer Therapy

Journal: Current Topics in Medicinal Chemistry
Volume: 19 Issue: 23 Year: 2019 Page: 2098-2113
Author(s): Fengqian Chen,Martin P. Alphonse,Yan Liu,Qi Liu

In Silico Identification and Analysis of Drug Resistant Mutants of ABL Tyrosine Kinase Based on Detrimental Missense Mutations

Journal: Current Signal Transduction Therapy
Volume: 6 Issue: 3 Year: 2011 Page: 396-404
Author(s): R. Rajasekaran, C. George Priya Doss, G. Arun Prasad, Rao Sethumadhavan

Expression of Human Tyrosine Kinase, Lck, in Yeast Saccharomyces cerevisiae: Growth Suppression and Strategy for Inhibitor Screening

Journal: Protein & Peptide Letters
Volume: 13 Issue: 9 Year: 2006 Page: 915-920
Author(s): Masashi Koyama, Shoko Saito, Rumiko Nakagawa, Iwao Katsuyama, Masakazu Hatanaka, Tadashi Yamamoto, Tsutomu Arakawa, Masao Tokunaga

Review Article

Back to the Bench? MEK and ERK Inhibitors for the Treatment of KRAS Mutant Lung Adenocarcinoma

Journal: Current Medicinal Chemistry
Volume: 25 Issue: 5 Year: 2018 Page: 558-574
Author(s): Jens Kohler,Marco Catalano,Chiara Ambrogio

Computer-Aided Drug Design for Cancer-Causing H-Ras p21 Mutant Protein

Journal: Letters in Drug Design & Discovery
Volume: 6 Issue: 1 Year: 2009 Page: 14-20
Author(s): Mannu Jayakanthan, Gulshan Wadhwa, Thangavel Madhan Mohan, Loganathan Arul, Ponnusamy Balasubramanian, Durai Sundar

Research Article

Structure-activity Relationship Study on Therapeutically Relevant EGFR Double Mutant Inhibitors

Journal: Medicinal Chemistry
Volume: 16 Issue: 1 Year: 2020 Page: 52-62
Author(s): Shehnaz Fatima,Subhash M. Agarwal

Basis for Resistance to Imatinib in 16 BCR-ABL Mutants as Determined Using Molecular Dynamics

Journal: Recent Patents on Anti-Cancer Drug Discovery
Volume: 4 Issue: 2 Year: 2009 Page: 164-173
Author(s): Tai-Sung Lee, Steven J. Potts, Maher Albitar

Molecular Dynamic Studies Unveil Potential Mechanisms of Resistance to Imatinib in BCR-ABL Mutants

Ebook: Topics in Anti-Cancer Research
Volume: 3 Year: 2014
Author(s): Tai-Sung Lee,Steven J. Potts,Maher Albitar
Doi: 10.2174/9781608059089114030011

Mutant Epidermal Growth Factor Receptors as Targets for Cancer Therapy

Journal: Current Cancer Drug Targets
Volume: 2 Issue: 2 Year: 2002 Page: 91-102
Author(s): I. A.J. Lorimer

Review Article

Kinase Inhibitors Involved in the Regulation of Autophagy: MolecularConcepts and Clinical Implications

Journal: Current Medicinal Chemistry
Volume: 30 Issue: 13 Year: 2023 Page: 1502-1528
Author(s): Srinivasa Rao Sirasanagandla,Kondaveeti Suresh Babu,Ramakrishna Gopala Sumesh Sofin

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