Search Result "In vitro-in vivo extrapolation (IVIVE)"


Quantitative Prediction of Glucuronidation in Humans Using the In Vitro- In Vivo Extrapolation Approach

Journal: Current Topics in Medicinal Chemistry
Volume: 13 Issue: 11 Year: 2013 Page: 1343-1352
Author(s): Baojian Wu,Dong Dong,Ming Hu,Shuxing Zhang

Application of Model-Based Approaches to Evaluate Hepatic Transporter-Mediated Drug Clearance: In vitro, In vivo, and In vitro-In vivo Extrapolation

Journal: Current Drug Metabolism
Volume: 17 Issue: 5 Year: 2016 Page: 456-468
Author(s): Zhihao Liu,Kexin Liu

The Impact of In Vitro Binding on In Vitro - In Vivo Extrapolations, Projections of Metabolic Clearance and Clinical Drug-Drug Interactions

Journal: Current Drug Metabolism
Volume: 7 Issue: 3 Year: 2006 Page: 251-264
Author(s): K. Grime, R. J. Riley

From in vitro Experiments to in vivo and Clinical Studies; Pros and Cons

Journal: Current Drug Discovery Technologies
Volume: 12 Issue: 4 Year: 2015 Page: 218-224
Author(s): Soodabeh Saeidnia, Azadeh Manayi, Mohammad Abdollahi

Human-Based In Vitro Experimental Systems for the Evaluation of Human Drug Safety

Journal: Current Drug Safety
Volume: 2 Issue: 3 Year: 2007 Page: 193-199
Author(s): Albert P. Li

Opinion Article

Evaluating Lean Liver Volume as a Potential Scaler for In Vitro-In Vivo Extrapolation of Drug Clearance in Obesity Using the Model Drug Antipyrine

Journal: Current Drug Metabolism
Volume: 21 Issue: 10 Year: 2020 Page: 746-750
Author(s): Jaydeep Sinha,Stephen B. Duffull,Bruce Green,Hesham S. Al-Sallami

Impact of Input Parameters on the Prediction of Hepatic Plasma Clearance Using the Well-Stirred Model

Journal: Current Drug Metabolism
Volume: 11 Issue: 7 Year: 2010 Page: 583-594
Author(s): Hong Wan, Peter Bold, Lars-Olof Larsson, Johan Ulander, Sheila Peters, Boel Lofberg, Anna-Lena Ungell, Mats Nagard, Antonio Llinas

Evaluation of Human Pharmacokinetics, Therapeutic Dose and Exposure Predictions Using Marketed Oral Drugs

Journal: Current Drug Metabolism
Volume: 8 Issue: 5 Year: 2007 Page: 463-479
Author(s): D.F. McGinnity, J. Collington, R.P. Austin, R.J. Riley

Scaling Factors for the Extrapolation of In Vivo Metabolic Drug Clearance From In Vitro Data: Reaching a Consensus on Values of Human Micro-somal Protein and Hepatocellularity Per Gram of Liver

Journal: Current Drug Metabolism
Volume: 8 Issue: 1 Year: 2007 Page: 33-45
Author(s): Zoe E. Barter, Martin K. Bayliss, Philip H. Beaune, Alan R. Boobis, David J. Carlile, Robert J. Edwards, J. Brian Houston, Brian G. Lake, John C. Lipscomb, Olavi R. Pelkonen, Geoffrey T. Tucke, Amin Rostami-Hodjegan

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