Search Result "Hit-to-lead (H2L)"


Trends in Hit-to-Lead: An Update

Ebook: Frontiers in Medicinal Chemistry
Volume: 3 Year: 2006
Author(s):
Doi: 10.2174/978160805206610603010653

Opportunities Offered by Fragment-Based Drug Design in Antibiotic Development

Ebook: Frontiers in Anti-Infective Drug Discovery
Volume: 8 Year: 2020
Author(s): Sanjay Yapabandara,Lorna Wilkinson-White,Sandro Ataide,Ann H. Kwan
Doi: 10.2174/9789811412387120080005

ADME Optimization and Toxicity Assessment in Drug Discovery

Ebook: Frontiers in Medicinal Chemistry
Volume: 8 Year: 2016
Author(s): Gary W. Caldwell
Doi: 10.2174/9781681081755116080003

Facts, Figures and Trends in Lead Generation

Journal: Current Topics in Medicinal Chemistry
Volume: 4 Issue: 6 Year: 2004 Page: 569-580
Author(s): Rebecca Deprez-Poulain, Benoit Deprez

Review Article

The In Silico Drug Discovery Toolbox: Applications in Lead Discovery and Optimization

Journal: Current Medicinal Chemistry
Volume: 26 Issue: 2 Year: 2019 Page: 3838-3873
Author(s): Agostino Bruno,Gabriele Costantino,Luca Sartori,Marco Radi

Review Article

Can Untargeted Metabolomics Be Utilized in Drug Discovery/Development?

Journal: Current Topics in Medicinal Chemistry
Volume: 17 Issue: 24 Year: 2017 Page: 2716-2739
Author(s): Gary W. Caldwell,Gregory C. Leo

Computer Aided Drug Design Approaches for Identification of Novel Autotaxin (ATX) Inhibitors

Journal: Current Medicinal Chemistry
Volume: 23 Issue: 17 Year: 2016 Page: 1708-1724
Author(s): Eleni Vrontaki,Georgia Melagraki,Eleanna Kaffe,Thomas Mavromoustakos,George Kokotos,Vassilis Aidinis,Antreas Afantitis

The SeeDs Approach: Integrating Fragments into Drug Discovery

Journal: Current Topics in Medicinal Chemistry
Volume: 7 Issue: 1 Year: 2007 Page: 1568-1581
Author(s): Roderick E. Hubbard, Ben Davis, Ijen Chen, Martin J. Drysdale

Targeting Monoamine Oxidases with Multipotent Ligands: An Emerging Strategy in the Search of New Drugs Against Neurodegenerative Diseases

Journal: Current Medicinal Chemistry
Volume: 18 Issue: 3 Year: 2011 Page: 4568-4587
Author(s): L. Pisani, M. Catto, F. Leonetti, O. Nicolotti, A. Stefanachi, F. Campagna, A. Carotti

Considering Autotaxin Inhibitors in Terms of 2D-QSAR and 3D-Mapping- Review and Evaluation

Journal: Current Medicinal Chemistry
Volume: 22 Issue: 1 Year: 2015 Page: 1428-1461
Author(s): Sotirios Katsamakas, Eleftherios Bermperoglou, Dimitra Hadjipavlou-Litina

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