Search Result "Hit identification"
Increasing the Odds of Drug Hit Identification by Screening Against Receptor Homologs?
Journal: Letters in Drug Design & Discovery
Volume: 3 Issue: 3 Year: 2006 Page: 200-204
Author(s): Z. L. Ji, Z. R. Li, J. F. Wang, C. Z. Cai, L. Y. Han, C. J. Zheng, Y. Z. Chen
Rational Prediction with Molecular Dynamics for Hit Identification
Journal: Current Topics in Medicinal Chemistry
Volume: 12 Issue: 18 Year: 2012 Page: 2002-2012
Author(s): Sara E. Nichols,Robert V. Swift,Rommie E. Amaro
Rational Design Approaches to Chemical Libraries for Hit Identification
Journal: Current Drug Discovery Technologies
Volume: 3 Issue: 1 Year: 2006 Page: 49-65
Author(s): Konstantin V. Balakin, Alexander V. Kozintsev, Alex S. Kiselyov, Nikolay P. Savchuk
Novel, Acidic CCR2 Receptor Antagonists: From Hit to Lead
Journal: Letters in Drug Design & Discovery
Volume: 4 Issue: 3 Year: 2007 Page: 185-191
Author(s): D. Zou, H.-X. Zhai, J. Eckman, P. Higgins, M. Gillard, L. Knerr, S. Carre, P. Pasau, P. Collart, J. Grassi
Lead Generation - Enhancing the Success of Drug Discovery by Investing in the Hit to Lead Process
Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 6 Issue: 1 Year: 2003 Page: 51-66
Author(s): Alexander Alanine, Matthias Nettekoven, Edward Roberts, Andrew W. Thomas
Efficient Optimization Strategy for Marginal Hits Active Against abl Tyrosine Kinases
Journal: Current Drug Discovery Technologies
Volume: 1 Issue: 3 Year: 2004 Page: 201-210
Author(s): Sergey E. Tkachenko, Ilya Okun, Konstantin V. Balakin, Charles E. Petersen, Yan A. Ivanenkov, Nikolay P. Savchuk, Andrey A. Ivashchenko
Enzyme Kinetics and Hit Validation in Fluorimetric Protease Assays
Journal: Current Topics in Medicinal Chemistry
Volume: 10 Issue: 3 Year: 2010 Page: 368-382
Author(s): Stephanie Ludewig, Markus Kossner, Markus Schiller, Knut Baumann, Tanja Schirmeister
The Identification, Characterization and Optimization of Small Molecule Probes of Cysteine Proteases: Experiences of the Penn Center for Molecular Discovery with Cathepsin B and Cathepsin L
Journal: Current Topics in Medicinal Chemistry
Volume: 9 Issue: 1 Year: 2009 Page: 1206-1216
Author(s): Donna M. Huryn, Amos B. Smith III
NMR Screening and Hit Validation in Fragment Based Drug Discovery
Journal: Current Topics in Medicinal Chemistry
Volume: 11 Issue: 1 Year: 2011 Page: 43-67
Author(s): Ramon Campos-Olivas
Identification of Nitric Oxide Donors by Biomimetic HTS Application
Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 8 Issue: 4 Year: 2005 Page: 347-352
Author(s): Gyorgy T. Balogh, Balazs Dalmadi, Attila Bielik, Gyorgy M. Keseru