Search Result "GPCR ligand binding modes"


GPCR Binding Technologies: An Overview

Journal: Current Topics in Medicinal Chemistry
Volume: 15 Issue: 24 Year: 2015 Page: 2476-2483
Author(s): Christel Franchet,Ismet Dorange

The Therapeutic Potential of Allosteric Ligands for Free Fatty Acid Sensitive GPCRs

Journal: Current Topics in Medicinal Chemistry
Volume: 13 Issue: 1 Year: 2013 Page: 14-25
Author(s): Brian D. Hudson, Trond Ulven, Graeme Milligan

The Role of Binding Kinetics in GPCR Drug Discovery

Journal: Current Topics in Medicinal Chemistry
Volume: 15 Issue: 24 Year: 2015 Page: 2504-2522
Author(s): David C. Swinney,Brad A. Haubrich,Isabelle Van Liefde,Georges Vauquelin

Using Silico Methods Predicting Ligands for Orphan GPCRs

Journal: Current Protein & Peptide Science
Volume: 7 Issue: 5 Year: 2006 Page: 459-464
Author(s):

G Protein-Coupled Receptor Transmembrane Binding Pockets and their Applications in GPCR Research and Drug Discovery: A Survey

Journal: Current Topics in Medicinal Chemistry
Volume: 11 Issue: 1 Year: 2011 Page: 1902-1924
Author(s): Nicole A. Kratochwil, Silvia Gatti-McArthur, Marius C. Hoener, Lothar Lindemann, Andreas D. Christ, Luke G. Green, Wolfgang Guba, Rainer E. Martin, Pari Malherbe, Richard H. P. Porter, Jay P. Slack, Marcel Winnig, Henrietta Dehmlow, Uwe Grether, Cornelia Hertel, Robert Narquizian, Constantinos G. Panousis, Sabine Kolczewski, Lucinda Steward

Review Article

Class A GPCRs: Structure, Function, Modeling and Structure-based Ligand Design

Journal: Current Pharmaceutical Design
Volume: 23 Issue: 29 Year: 2017 Page: 4390-4409
Author(s): Xiaojing Cong,Jeremie Topin,Jerome Golebiowski

High Throughput Screening for Orphan and Liganded GPCRs

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 11 Issue: 3 Year: 2008 Page: 195-215
Author(s): Shou-Hua Xiao, Jeff D. Reagan, Paul H. Lee, Angela Fu, Ralf Schwandner, Xiaoning Zhao, Johannes Knop, Holger Beckmann, Stephen W. Young

Functional Selectivity in GPCR Signaling: Understanding the Full Spectrum of Receptor Conformations

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 12 Issue: 9 Year: 2012 Page: 817-830
Author(s): E. Goupil,S. A. Laporte,T. E. Hebert

Validated Ligand Binding Sites in CCK Receptors. Next Step: Computer-Aided Design of Novel CCK Ligands

Journal: Current Topics in Medicinal Chemistry
Volume: 7 Issue: 1 Year: 2007 Page: 1243-1247
Author(s): Irina G. Tikhonova, Esther Marco, Elodie Lahlou-Archer, Ingrid Langer, Magali Foucaud, Bernard Maigret, Daniel Fourmy

The Selection and Design of GPCR Ligands: From Concept to the Clinic

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 7 Issue: 5 Year: 2004 Page: 441-452
Author(s): Mark Ashton, Michael H. Charlton, Matthias K. Schwarz, Russell J. Thomas, Mark Whittaker

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