Search Result "Dxr inhibitors"


Inhibition of 1-Deoxy-D-Xylulose-5-Phosphate Reductoisomerase (Dxr): A Review of the Synthesis and Biological Evaluation of Recent Inhibitors

Journal: Current Topics in Medicinal Chemistry
Volume: 12 Issue: 7 Year: 2012 Page: 706-728
Author(s): Emily R. Jackson,Cynthia S. Dowd

Targeting the Methyl Erythritol Phosphate (MEP) Pathway for Novel Antimalarial, Antibacterial and Herbicidal Drug Discovery: Inhibition of 1-Deoxy-D-Xylulose-5-Phosphate Reductoisomerase (DXR) Enzyme

Journal: Current Pharmaceutical Design
Volume: 13 Issue: 1 Year: 2007 Page: 1161-1177
Author(s): Nidhi Singh, Gweneal Cheve, Mitchell A. Avery, Christopher R. McCurdy

Inhibition Studies on Enzymes Involved in Isoprenoid Biosynthesis. Focus on Two Potential Drug Targets: DXR and IDI-2 Enzymes

Journal: Current Enzyme Inhibition
Volume: 7 Issue: 2 Year: 2011 Page: 79-95
Author(s): Jerome de Ruyck, Johan Wouters, C. Dale Poulter

The Malarial Drug Target Plasmodium falciparum 1-Deoxy-D-Xylulose-5- Phosphate Reductoisomerase (PfDXR): Development of a 3-D Model for Identification of Novel, Structural and Functional Features and for Inhibitor Screening (Supplementary Information)

Journal: Protein & Peptide Letters
Volume: 17 Issue: 1 Year: 2010 Page: 109-120
Author(s): Jessica L. Goble, Matthew R. Adendorff, Tjaart A.P. de Beer, Linda L. Stephens, Gregory L. Blatch

The Druggable Antimalarial Target PfDXR: Overproduction Strategies and Kinetic Characterization

Journal: Protein & Peptide Letters
Volume: 20 Issue: 2 Year: 2013 Page: 115-124
Author(s): Jessica L. Goble,Hailey Johnson,Jaco de Ridder,Linda L. Stephens,Abraham Louw,Gregory L. Blatch,Aileen Boshoff

Review Article

Flavonoids as P-gp Inhibitors: A Systematic Review of SARs

Journal: Current Medicinal Chemistry
Volume: 26 Issue: 25 Year: 2019 Page: 4799-4831
Author(s): Jiahua Cui,Xiaoyang Liu,Larry M.C. Chow

Key Targets and Relevant Inhibitors for the Drug Discovery of Tuberculosis

Journal: Current Drug Targets
Volume: 14 Issue: 6 Year: 2013 Page: 676-699
Author(s): Xiuming Xiong, Zhijian Xu, Zhuo Yang, Yingtao Liu, Di Wang, Mei Dong, Emily J. Parker, Weiliang Zhu

Research Article

Novel Potent Plasmepsin-I (PMI) Inhibitors: An In-Silico Approach

Journal: Current Proteomics
Volume: 13 Issue: 3 Year: 2016 Page: 196-205
Author(s): Kamal Kumar Chaudhary,Utkarsh Raj,Pritish Kumar Varadwaj,Nidhi Mishra

The MEP Pathway: A New Target for the Development of Herbicides, Antibiotics and Antimalarial Drugs

Journal: Current Pharmaceutical Design
Volume: 10 Issue: 1 Year: 2004 Page: 2391-2400
Author(s): M. Rodriguez-Concepcion

Research Article

PLK1 Inhibition Radiosensitizes Breast Cancer Cells, but Shows Low Efficacy as Monotherapy or in Combination with other Cytotoxic Drugs

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 18 Issue: 9 Year: 2018 Page: 1252-1257
Author(s): María Sol Brassesco,Julia Alejandra Pezuk,Karina Bezerra Salomão,Gabriela Molinari Roberto,Carlos Alberto Scrideli,Luiz Gonzaga Tone

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