Search Result "DMPK assays"


Utility of Mass Spectrometry for In-Vitro ADME Assays

Journal: Current Drug Metabolism
Volume: 7 Issue: 5 Year: 2006 Page: 467-477
Author(s): Inhou Chu, Amin A.Nomeir

The Influence of DMPK as an Integrated Partner in Modern Drug Discovery

Journal: Current Drug Metabolism
Volume: 3 Issue: 5 Year: 2002 Page: 527-550
Author(s): Robert J. Riley, Iain J. Martin, Anne E. Cooper

Research Article

Further Considerations Towards an Effective and Efficient Oncology Drug Discovery DMPK Strategy

Journal: Current Drug Metabolism
Volume: 21 Issue: 2 Year: 2020 Page: 145-162
Author(s): Beth Williamson,Nicola Colclough,Adrian John Fretland,Barry Christopher Jones,Rhys Dafydd Owen Jones,Dermot Francis McGinnity

Advances in the Integration of Drug Metabolism into the Lead Optimization Paradigm

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 9 Issue: 6 Year: 2009 Page: 703-716
Author(s): Walter A. Korfmacher

Molecular Effects of the CTG Repeats in Mutant Dystrophia Myotonica Protein Kinase Gene

Journal: Current Genomics
Volume: 9 Issue: 8 Year: 2008 Page: 509-516
Author(s): Beatriz Llamusi, Ruben Artero

open access plus

Efficiency in Drug Discovery: Liver S9 Fraction Assay As a Screen for Metabolic Stability

Journal: Drug Metabolism Letters
Volume: 10 Issue: 2 Year: 2016 Page: 83-90
Author(s): Samantha J. Richardson, April Bai, Ashutosh A. Kulkarni, Mehran F. Moghaddam

Identifying a Higher Throughput Assay for Metabolism Dependent Inhibition (MDI)

Journal: Drug Metabolism Letters
Volume: 4 Issue: 2 Year: 2010 Page: 104-113
Author(s): Mahmud Kajbaf, Emiliano Palmieri, Raffaele Longhi, Stefano Fontana

The Role of Exploratory Drug Metabolism and Pharmacokinetics in New Drug Research: Case Study-Selection of a Thrombin Receptor Antagonist for Development

Journal: Current Pharmaceutical Design
Volume: 15 Issue: 1 Year: 2009 Page: 2262-2269
Author(s): Yunsheng Hsieh, K.-C. Cheng, Yuguang Wang, Samuel Chackalamannil, Yan Xia, Walter A. Korfmacher, Ronald E. White

A Transcellular Assay to Assess the P-gp Inhibition in Early Stage of Drug Development

Journal: Drug Metabolism Letters
Volume: 6 Issue: 4 Year: 2012 Page: 285-291
Author(s): Jan-Shiang Taur, Edgar L. Schuck, Nancy Y. Wong

Increasing Speed and Throughput When Using HPLC-MS/MS Systems forDrug Metabolism and Pharmacokinetic Screening

Journal: Current Drug Metabolism
Volume: 7 Issue: 5 Year: 2006 Page: 479-489
Author(s): Yunsheng Hsieh, Walter A. Korfmacher

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