Search Result "tissue-to-plasma partition coefficient"


Research Article

Prediction of Tissue to Plasma Concentration Ratios of Drugs in the Rat from Experimentally Estimated Volume of Distribution: Application of Allometry

Journal: Current Drug Metabolism
Volume: 19 Issue: 2 Year: 2018 Page: 155-164
Author(s): Iftekhar Mahmood

Do We Need to Optimize Plasma Protein and Tissue Binding in Drug Discovery?

Journal: Current Topics in Medicinal Chemistry
Volume: 11 Issue: 4 Year: 2011 Page: 450-466
Author(s): Xingrong Liu, Cuiping Chen, Cornelis E.C.A. Hop

Liposaccharides for Improved Oral Delivery of Tobramycin

Journal: Drug Delivery Letters
Volume: 2 Issue: 2 Year: 2012 Page: 92-97
Author(s): Adel S. Abdelrahim, Pavla Simerska, Istvan Toth

Insight into Tissue Unbound Concentration: Utility in Drug Discovery and Development

Journal: Current Drug Metabolism
Volume: 14 Issue: 3 Year: 2013 Page: 324-340
Author(s): T. Thanga Mariappan,Sandhya Mandlekar,Punit Marathe

Prediction of Distribution of Neutral, Acidic and Basic Structurally Diverse Compounds Between Blood and Brain by the Nonlinear Methodology

Journal: Medicinal Chemistry
Volume: 4 Issue: 2 Year: 2008 Page: 170-189
Author(s): Huabei Zhang, Shaoping Hu, Yaling Zhang

Comparative Efflux of Saquinavir, Ritonavir and Lopinavir from Primary Human Cells

Journal: Drug Metabolism Letters
Volume: 4 Issue: 4 Year: 2010 Page: 241-245
Author(s): Bilge Diker, Omar Janneh, Rolf P.G. van Heeswijk, Karen F.T. Copeland

The Use of Immobilised Artificial Membrane (IAM) Chromatography for Determination of Lipophilicity

Journal: Current Computer-Aided Drug Design
Volume: 2 Issue: 4 Year: 2006 Page: 341-352
Author(s): Francesco Barbato

Review Article

Current State and Future Perspectives in QSAR Models to Predict Blood- Brain Barrier Penetration in Central Nervous System Drug R&D

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 17 Issue: 3 Year: 2017 Page: 247-257
Author(s): Juan F. Morales,Sebastian Scioli Montoto,Pietro Fagiolino,Maria E. Ruiz

Synthesis, Physicochemical Properties and In Vitro Permeation Studies of New Ketorolac Ester Derivatives

Journal: Current Drug Delivery
Volume: 4 Issue: 3 Year: 2007 Page: 205-210
Author(s): Carmelo Puglia, Rosanna Filosa, Antonella Peduto, Paolo de Caprariis, Gianpiero Boatto, Maria Nieddu, Natale Alfredo Santagati, Francesco Bonina

Research Article

Formulation and Characterization of Phytosomes as Drug Delivery Systemof Formononetin: An Effective Anti-Osteoporotic Agent

Journal: Current Drug Delivery
Volume: 21 Issue: 2 Year: 2024 Page: 261-270
Author(s): Sandeep K. Singh,Jiaur R. Gayen

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