Search Result "positive allosteric modulators (PAM)"


Research Article

Characterization of a New Positive Allosteric Modulator of AMPA Receptors - PAM-43: Specific Binding of the Ligand and its Ability to Potentiate AMPAR Currents

Journal: Current Molecular Pharmacology
Volume: 13 Issue: 3 Year: 2020 Page: 216-223
Author(s): Tatiana V. Vyunova,Lioudmila A. Andreeva,Konstantin V. Shevchenko,Vladimir V. Grigoriev,Vladimir A. Palyulin,Mstislav I. Lavrov,Ekaterina V. Bondarenko,Elena E. Kalashnikova,Nikolay F. Myasoedov

Advances in the Discovery of Novel Positive Allosteric Modulators of the α7 Nicotinic Acetylcholine Receptor

Journal: Recent Patents on CNS Drug Discovery (Discontinued)
Volume: 2 Issue: 2 Year: 2007 Page: 99-106
Author(s): Ramin Faghih, Gregory A. Gfesser, Murali Gopalakrishnan

SAR Studies on Carboxylic Acid Series M1 Selective Positive Allosteric Modulators (PAMs)

Journal: Current Topics in Medicinal Chemistry
Volume: 14 Issue: 15 Year: 2014 Page: 1738-1754
Author(s): Scott D. Kuduk,Douglas C. Beshore

Letter Article open access plus

Challenges in the Discovery and Optimization of mGlu2/4 Heterodimer Positive Allosteric Modulators

Journal: Letters in Drug Design & Discovery
Volume: 16 Issue: 12 Year: 2019 Page: 1387-1394
Author(s): Mark Gallant Fulton,Matthew Thomas Loch,Caroline Anne Cuoco,Alice Lambert Rodriguez,Emily Days,Paige Newton Vinson,Krystian Andrezej Kozek,Charles David Weaver,Anna Louise Blobaum,Peter Jeffrey Conn,Colleen Marie Niswender,Craig William Lindsley

Positive Allosteric Modulators for mGluR2 Receptors: A Medicinal Chemistry Perspective

Journal: Current Topics in Medicinal Chemistry
Volume: 14 Issue: 15 Year: 2014 Page: 1771-1788
Author(s): Gyorgy Szabo,Gyorgy Miklos Keseru

Progress in the Developement of Positive Allosteric Modulators of the Metabotropic Glutamate Receptor 2

Journal: Current Medicinal Chemistry
Volume: 18 Issue: 1 Year: 2011 Page: 47-68
Author(s): A. A. Trabanco, J. M. Cid, H. Lavreysen, G. J. Macdonald, G. Tresadern

SAR Studies on mGlu5 Receptor Positive Allosteric Modulators (2003- 2013)

Journal: Current Topics in Medicinal Chemistry
Volume: 14 Issue: 15 Year: 2014 Page: 1789-1841
Author(s): Junliang Hao,Hui Xiong

Allosteric Modulators for mGlu Receptors

Journal: Current Neuropharmacology
Volume: 5 Issue: 3 Year: 2007 Page: 187-194
Author(s): F. Gasparini, W. Spooren

Positive Allosteric Modulators (PAMs) of Metabotropic Glutamate Receptor 5 (mGluR5) Attenuate Microglial Activation

Journal: CNS & Neurological Disorders - Drug Targets
Volume: 13 Issue: 4 Year: 2014 Page: 558-566
Author(s): Fengtian Xue,Bogdan A. Stoica,Marie Hanscom,Shruti V. Kabadi,Alan I. Faden

Desformylflustrabromine: A Novel Positive Allosteric Modulator for beta2 Subunit Containing Nicotinic Receptor Sub-Types

Journal: Current Pharmaceutical Design
Volume: 22 Issue: 14 Year: 2016 Page: 2057-2063
Author(s): Anshul A. Pandya

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